Pulmonary Hypertension Association Registry
Recruiting
The PHA Registry (PHAR) is a national study about people who have pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). PHAR collects information from people with PAH and CTEPH who are cared for in participating PHA-accredited Pulmonary Hypertension Care Centers throughout the U.S. PHAR will determine how people with PAH and CTEPH are evaluated, tested, and treated, and will observe how well these participants do. The goal is to see if people with PH a... Read More
Gender:
All
Ages:
All
Trial Updated:
04/01/2020
Locations: Indiana University Health, Indianapolis, Indiana
Conditions: Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Hypertension
Onco4D(TM) Biodynamic Chemotherapy Selection for Bladder Cancer Patients
Recruiting
Millions of cancer patients every year receive chemotherapy with only a 20-60% probability of pathological response, while most experience adverse side effects that lower quality of life without prolonging it. Reliable identification of ineffective therapies can eliminate needless human suffering while increasing overall probability of positive response to treatment. Chemotherapy resistance profiling entails testing whether a patient exhibits strong resistance to a therapy prior to its final sel... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/09/2020
Locations: Animated Dynamics, Inc., Indianapolis, Indiana
Conditions: Bladder Cancer
Onco4D(TM) Biodynamic Chemotherapy Selection for Breast Cancer Patients
Recruiting
Millions of cancer patients every year receive chemotherapy with only a 20-60% probability of pathological response, while most experience adverse side effects that lower quality of life without prolonging it. Reliable identification of ineffective therapies can eliminate needless human suffering while increasing overall probability of positive response to treatment. Chemotherapy resistance profiling entails testing whether a patient exhibits strong resistance to a therapy prior to its final sel... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/09/2020
Locations: Animated Dynamics, Inc., Indianapolis, Indiana
Conditions: Breast Cancer
Vagus Nerve Response in Gastroparesis Patients
Recruiting
This study aims to characterize how vagus nerve compound action potentials (CNAPs) conduct along the vagus nerve in gastroparetic patients receiving GES therapy using a flexible, non-invasive multielectrode array (MEA).
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
12/18/2019
Locations: Indiana University Hosptial, Indianapolis, Indiana
Conditions: Gastroparesis
Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair
Recruiting
The objective of this trial is to assess the safety and effectiveness of the study device in subjects with degenerative mitral valve disease receiving a mitral valve repair without cardiopulmonary bypass (treatment group) when compared to subjects receiving mitral valve repair using standard surgical techniques with cardiopulmonary bypass (control group).
Gender:
All
Ages:
21 years and above
Trial Updated:
12/04/2019
Locations: Franciscan Health, Indianapolis, Indiana
Conditions: Mitral Valve Insufficiency
Bio-mechanical Reasoning and Lateral Specificity of Upper Cervical Joint Mobilization
Recruiting
Participants with limited neck rotation are recruited to determine if manual therapy (joint stretching) techniques applied in a bio-mechanically correct sequence will improve neck motion, function and pain better than if the manual therapy is applied in the opposite direction. Each participant will receive both the correct and the incorrect applications in randomized order with each treatment separated by 2-3 days. Improvement in neck motion, function and pain will be assessed after each session... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
11/26/2019
Locations: Indiana University Health - West Hospital, Avon, Indiana
Conditions: Neck Pain
Feasibility Study of the Intravascular Ventricular Assist System (iVAS)
Recruiting
The purpose of this feasibility study is to assess the preliminary safety and clinical performance of the intravascular ventricular assist system (iVAS).
Gender:
All
Ages:
18 years and above
Trial Updated:
11/11/2019
Locations: Saint Vincent Hospital, Indianapolis, Indiana
Conditions: Heart Failure NYHA Class III, Heart Failure NYHA Class IV
FFR vs. icECG in Coronary Bifurcations
Recruiting
The study hypothesis: it is possible to use icECG recorded from regular PCI wire to predict significance of SB ostial stenosis after main vessel stenting in coronary bifurcation lesions.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
08/18/2019
Locations: Indiana-Purdue University, Indianapolis, Indiana
Conditions: Coronary Artery Disease
Different Levels of Patient Education for Care of Ostomy Site
Recruiting
This is a randomized study of standard versus extra ostomy education.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
02/19/2019
Locations: Indiana University Health North Hospital, Carmel, Indiana
Conditions: Ostomy
Testing Utility of Commercially Available Sleep Trackers for Physician-Patient Communication
Recruiting
Sleep related disorders are common in primary care practice. Sleep wear related data has not been utilized to improve sleep related communication between patients and providers. The study team is conducting a randomized study to improve physical-patient communication regarding sleep through a novel intervention based upon sleep wear and the Sleeplife® app.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/03/2019
Locations: Regenstrief Institute, Indianapolis, Indiana
Conditions: Insomnia
Cerebrotendinous Xanthomatosis (CTX) Prevalence Study
Recruiting
This is an observational, multicenter study to determine the prevalence of Cerebrotendinous Xanthomatosis (CTX) in patient populations diagnosed with early-onset idiopathic bilateral cataracts. Patients who are potentially eligible for study participation will be identified through a chart review of patients who were seen at each study site prior to that site's initiation, or by entering care at the site while the site is participating in the trial.
Gender:
All
Ages:
Between 2 years and 21 years
Trial Updated:
11/07/2018
Locations: Riley Hospital for Children, Indianapolis, Indiana
Conditions: Cerebrotendinous Xanthomatosis (CTX)
Concurrent Treatment for Patients With Cervical Radiculopathy
Recruiting
This study evaluates the effectiveness of two treatment interventions in patients with cervical radiculopathy. One group will receive a concurrent approach using traction and neuromobilizations. The other group will receive the sequential approach of traction and neuromobilizations
Gender:
All
Ages:
18 years and above
Trial Updated:
10/17/2018
Locations: Michiana Orthopaedics and Sports Physical Therapy, Mishawaka, Indiana
Conditions: Spinal Nerve Root Disorder Nos