Michigan Clinical Trials

A listing of Michigan clinical trials actively recruiting patient volunteers.

Making the decision to participate in a clinical trial is a very personal one. Some individuals do it because they have run out of options and want to try a new experimental treatment in the hope it might help their condition, while others do it because they want to do their part helping the clinical community move forward and potentially help cure many people down the line. For individuals looking to participate, there are a wide array of clinical trials in Michigan looking for participants who can commit to seeing the trials through. The biggest city of Michigan is Detroit, "The Motor City" that was central to America's auto industry for decades. Lansing is the capital, while Ann Arbor and Grand Rapids round out the list with some of the most beautiful views of any urban area in America. Michigan boasts the longest freshwater coastline of any U.S. state, adding to its reputation for outdoor recreation. Today's Michigan is increasingly building businesses in professional services, health, and education. Medical care has kept up with the times, with the University of Michigan Hospitals and Health Centers blazing the trail toward world class community health.

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2346 trials found

A Study to Evaluate the Effect of Sodium Zirconium Cyclosilicate on Chronic Kidney Disease (CKD) Progression in Participants With CKD and Hyperkalaemia or at Risk of Hyperkalaemia

NCT05056727

The purpose of this study is to evaluate the effect of Sodium Zirconium Cyclosilicate (SZC), as adjunct to ACEi/ARB therapy (lisinopril or valsartan), on slowing CKD progression (assessed as the reduction in participant's glomerular filtration rate [eGFR] decline over time) in participants with hyperkalaemia or at high risk of hyperkalaemia.

Conditions: Renal Insufficiency, Chronic, Hyperkalemia

Effectiveness of Aquamin® in Mitigating Halitosis

NCT05058638

The purpose of this study is to assess whether Aquamin®, a multi-mineral natural product from red marine algae, can help reduce halitosis when taken for 90 days.

Conditions: Healthy, Halitosis

Developing Text-based Support for Parents of Adolescents After an Emergency Department Visit

NCT05058664

The researchers seek to develop a text message intervention for caregivers of adolescents at elevated suicide risk following discharge from emergency department (ED) care.

Conditions: Suicide
Phase: Not Applicable

This SCR-103 Protocol Will Permit Sites to Proactively Assess TAA, HLA and HPV-16 Status in Patients With Selected Solid Tumors to Determine Suitability for Repertoire Immune Medicines Treatment Protocols.

NCT05061940

The purpose of this study is to obtain archived tumor tissue or pre-existing antigen expression data from patients with Head and Neck, Cervical, Melanoma and Non-Small Cell Lung Cancers to assess antigen expression and patient suitability for a Repertoire Immune Medicines Treatment Protocol.

Conditions: Head and Neck Cancer, Melanoma, HPV-Related Malignancy, HPV-Related Carcinoma, HPV-Related Cervical Carcinoma, HPV Positive Oropharyngeal Squamous Cell Carcinoma, Lung Cancer, Nonsmall Cell, Melanoma (Skin)

A 1-year Trial to Inform About Long-term Exposure to Eptinezumab in Participants With Chronic Cluster Headache (cCH)

NCT05064397

The main goal of this trial is to inform about long-term safety and tolerability of eptinezumab in participants with chronic cluster headache.

Conditions: Chronic Cluster Headache

Axonics SacRal NeuromodulaTIon System RegisTRY Study

NCT05064384

To assess the post-market clinical outcomes with use of the Axonics Sacral Neuromodulation System(s).

Conditions: Urinary Retention, Urinary Urge Incontinence, Urgency-Frequency, Fecal Incontinence

Research Study Looking at How Well Semaglutide Works in People Suffering From Obesity and Knee Osteoarthritis

NCT05064735

This study will look at participants body weight from the start to the end of the study. It will also look at how much pain participants have in participants knee from the start to the end of the study and how this affects participants daily life. This is to compare the effect on body weight and pain in the knee in people taking semaglutide with people taking "dummy" medicine. Participants will either get semaglutide or "dummy" medicine. Which treatment participants get is decided by chance. Pa ...

Conditions: Obesity

Mag Con: Efficacy of Oral Mag. in Acute Concussion in Adolescents

NCT05065528

This randomized trial will compare the clinical efficacy of oral magnesium oxide, acetaminophen and ondansetron, to that of PO acetaminophen and ondansetron in the treatment of adolescents presenting within 48 hours of a mild traumatic brain injury. Our primary endpoint will be to evaluate if magnesium has an impact on patient's Post-Concussion Symptom Severity Score Index.

Conditions: Concussion, Mild, Traumatic Brain Injury, Mild
Phase: Not Applicable

Cyclic Vomiting: Droperidol

NCT05065567

The purpose of this study is to compare two commonly used agents for the treatment of cyclic vomiting to see if one agent is inferior to the other in time to improvement in symptoms, need for repeat or rescue medications, treatment failures and complications/side effects.

Conditions: Cyclic Vomiting Syndrome

OMT as an Adjunctive Treatment in MDD

NCT05065580

participants will be receiving OMT 1x/week for 8 weeks. Each appointment with be a duration of 30 minutes. Patients will be required to fill out PHQ-9 and SSS-8 questionnaires before beginning the study and following the conclusion of the study.

Conditions: Major Depressive Disorder
Phase: Not Applicable

MIDAS Cluster Randomized Controlled Trial of Implementation Strategies to Optimize Use of Medications in VA Clinical Settings

NCT05065502

Scientific advances are constantly leading to better treatments. However, it is quite challenging for healthcare systems, including VA, to ask very busy providers to change the way they practice. The MIDAS QUERI program will help providers improve the way they treat VA patients for three common conditions, using specific strategies to ensure the reliable delivery of these treatments. The first project will focus on reducing polypharmacy using the VIONE practice, developed in VA. The second proje ...

Conditions: Polypharmacy, Insomnia, Anticoagulants
Phase: Not Applicable

A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 in Participants With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy (NPDR)

NCT05066230

This Phase 3 Study will evaluate the efficacy and safety of KSI-301 in participants with moderately severe to severe non-proliferative diabetic retinopathy (NPDR).

Conditions: Non-proliferative Diabetic Retinopathy

Clinical trials vary in time; in total a single clinical trial may take up to 15 years to complete, and some longitudinal studies ask the participant to stay in touch for follow up questions for a few years after their participation in the study is finished. Depending on the goal and the design of a clinical trial, volunteers may be asked to stay on site for a set amount of nights; this happens because the researchers might want to monitor the participant's at different hours of the day or night. Some clinical research is also setup to compensate individuals, and paid clinical trials are not uncommon.

In Michigan, the University of Michigan division of research has one of the largest clinical trial and research centers in the state, where interested volunteers can enroll in studies for healthy or non-healthy individuals. The Barbara Ann Karmanos cancer institute in Detroit, Michigan also offers clinical trials for many types of cancers for both healthy and non-healthy individuals.

Volunteers who decide to participate in a clinical trial may be compensated for their time and travel expenses during their participation in the study. The compensation will vary depending on the type of study and level of participation required from the volunteer, but paid clinical trials in Michigan are very common.

Participating in a clinical trial is always completely voluntary. This means that nobody, regardless of their condition can be forced to participate nor can they be forced to continue participating in a trial if they wish to withdraw from the study. Non-healthy individuals who decide to enroll in a clinical trial after a suggestion from their doctor or to try an experimental treatment for their condition will never be denied care if they decide to drop out of the study.