Minnesota is currently home to 2108 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy
NCT01696721
Recruiting
In previous studies, Proton Beam Radiation Therapy (PBRT) has been found to show better results in treating patients with cancer, both because there is better control of where in the body the radiation is directed and because it is associated with less severe long term side effects. However, there is limited published data demonstrating these results. The goal of the Proton and Photon Consortium Registry (PPCR) is to enroll children treated with radiation in order to describe the population that... Read More
Gender:
All
Ages:
21 years and below
Trial Updated:
01/05/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Pediatric Patients Treated With Radiation Therapy
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A Study Evaluating the Safety and Pharmacokinetics of QTORIN Rapamycin 3.9% Anhydrous Gel in the Treatment of Adults With Pachyonychia Congenita
NCT05643872
Recruiting
PALV-08 is a multicenter, open-label treatment (OLT) study enrolling adults with Pachyonychia Congenita (PC) with genotyped keratin mutations KRT6A, KRT6B, KRT6C or KRT16 who were previously enrolled in the PALV-05 (VAPAUS) trial. The purpose of this OLT study is to investigate the safety of long term exposure and pharmacokinetics (PK) of QTORIN rapamycin 3.9% anhydrous gel or "PTX-022".
Gender:
All
Ages:
16 years and above
Trial Updated:
12/01/2022
Locations: Minnesota Clinical Study Center, New Brighton, Minnesota
Conditions: Pachyonychia Congenita
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Schulze Muscular Dystrophy Ability Clinical Study
NCT05409079
Recruiting
The primary objective of the Schulze study is to evaluate the function of the upper limbs of subjects diagnosed with neuromuscular disorders, with and without use of the Abilitech Assist device in the clinic and home environments. Functional outcomes will include documenting active range of motion and the ability to perform activities of daily living (ADLs) using the standardized Canadian Occupational Performance Measure (COPM) and the Role Evaluation of Activities of Life (REAL) assessments. Se... Read More
Gender:
All
Ages:
10 years and above
Trial Updated:
12/01/2022
Locations: Gillette Children's, Saint Paul, Minnesota
Conditions: Muscular Dystrophies, Spinal Muscular Atrophy, Duchenne Muscular Dystrophy, Limb Girdle Muscular Dystrophy, FSHD, Cerebral Palsy, Becker Muscular Dystrophy
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Evaluating the Safety and Efficacy of a Novel Accelerated Partial Breast Irradiation Regimen for patIents With Favorable Risk breaSt cancEr
NCT05591547
Recruiting
This study will use an adjuvant radiation therapy regimen called APBI (accelerated partial breast irradiation). APBI is a treatment option available to women considered to have an early stage, low-risk breast cancer. The standard external beam-based APBI treatment delivers treatments every other day for five treatments, over ten calendar days. The APBI in this study is modified and will deliver five once daily treatments over consecutive treatment days, with a slightly lower dose of radiation ea... Read More
Gender:
Female
Ages:
50 years and above
Trial Updated:
11/11/2022
Locations: Sanford Health, Worthington, Minnesota
Conditions: Breast Cancer
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Acute Optic Neuritis Network: an International Study That Invesitages Subjects With a First-ever Episode of Acute Inflammation of the Optic Nerve
NCT05605951
Recruiting
The goal of this observational study is to longitudinally investigating subjects with inaugural acute optic neuritis (ON). The main questions it aims to answer are: Does the time to corticosteroid treatment affect the visual outcome at 6 months in subjects with acute multiple sclerosis (MS)-, aquaporin 4-IgG positive (AQP4-IgG+) and myelin-oligodendrocyte-glycoprotein-IgG positive (MOG-IgG+) ON? How differ clinical, structural, and laboratory biomarkers in subjects with acute ON, including cli... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/31/2022
Locations: Departments of Neurology and Ophthalmology, Mayo Clinic, Rochester, Minnesota
Conditions: Demyelinating Diseases, Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorder Attack, Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease, Optic Neuritis
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Radioembolization of Primary and Secondary Liver Malignancies and The Effect On The Immune System
NCT03889093
Recruiting
The goal of this study is to understand the immunologic effects radioembolization has on the immune system. This will be done by evaluating the changes on biopsy, peripheral blood monocytes, and cytokines.
Gender:
All
Ages:
22 years and above
Trial Updated:
10/28/2022
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Hepatocellular Carcinoma, Secondary Malignant Neoplasm of Liver
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Safety and Effectiveness of the CustomFlex Artificial Iris Prosthesis for the Treatment of Iris Defects
NCT01860612
Recruiting
The purpose of this study is to study the long term safety and effectiveness of an artificial iris prosthesis for the treatment of iris defects.
Gender:
All
Ages:
3 years and above
Trial Updated:
10/21/2022
Locations: Minnesota Eye Consultants, Bloomington, Minnesota
Conditions: Full Aniridia, Partial Aniridia
Register for Updates
International Device Assisted Controlled Sequential Elevation CPR Registry
NCT05588024
Recruiting
The purpose of this prospective observational cardiopulmonary resuscitation (CPR) registry is to track the use and clinical outcomes from emergency medical systems across the US and Europe that have implemented a system of care approach applied rapidly to cardiac arrest that includes using the combination of an impedance threshold device (ITD), and either manual active compression-decompression (ACD) CPR device or automated compression device, with a Head Up CPR device.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/17/2022
Locations: AdvancedCPR Soluations, Edina, Minnesota
Conditions: Cardiac Arrest, Out-Of-Hospital
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Evaluating the Clinical Effectiveness of a Patient-specific Silicone Stent
NCT05050591
Recruiting
The goal of the trial is to establish a method, material, and patient-specific stent design that will last longer, fit better, and cause less trauma to the airway and the patient.
Gender:
All
Ages:
22 years and above
Trial Updated:
10/14/2022
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Pulmonary Disease, Chronic Obstructive
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Retrospective Non-interventional Study of Stiripentol Use in Dravet Patients in the USA
NCT05544058
Recruiting
The present study aims to collect data regarding the history of the disease, previous and current treatments, and the clinical status of Dravet patients during the 3 months prior to stiripentol initiation, the first 3 months on stiripentol and the last 3 months on stiripentol (irrespective of stiripentol discontinuation).
Gender:
All
Ages:
All
Trial Updated:
09/20/2022
Locations: Mayo clinic, Rochester, Minnesota
Conditions: Dravet Syndrome
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Electron Beam Intraoperative Radiation Therapy Following Chemoradiation in Patients With Pancreatic Cancer With Vascular Involvement
NCT03716531
Recruiting
This research study is studying an intervention as a possible treatment for pancreatic cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/07/2022
Locations: Mayo Clinic, Rochester, Rochester, Minnesota
Conditions: Pancreas Cancer
Register for Updates
MR-Guided Focused Ultrasound in the Treatment of Focal Epilepsy (EP001)
NCT02804230
Recruiting
The purpose of this study is to evaluate the feasibility, safety, and initial effectiveness of Exablate thermal ablation of a focal epileptic target area in the brain of patients suffering from medication-refractory epilepsy, using the Exablate transcranial system to produce multiple sonications targeted in the focus of interest. The investigators will establish the feasibility and collect data to establish the basic safety of this type of treatment as the basis for later studies that will evalu... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
09/07/2022
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Epilepsy
Register for Updates