Minnesota is currently home to 2104 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Artisan Aphakia Lens for the Correction of Aphakia in Children
NCT01547442
Recruiting
The purpose of this study is to determine the safety and effectiveness of the Artisan Aphakia Lens in the treatment of aphakia in children.
Gender:
All
Ages:
Between 2 years and 21 years
Trial Updated:
06/24/2022
Locations: University of Minnesota, MN Lions Children's Eye Clinic, Minneapolis, Minnesota
Conditions: Aphakia
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Multi-lead ECG to Effectively Optimize Resynchronization Devices: New CRT Recipients
NCT04083690
Recruiting
Cardiac resynchronization therapy (CRT), or atrial-synchronized biventricular (BiV) pacing, is an FDA-approved device therapy option for heart failure (HF) patients with reduced left ventricular ejection fraction and electrical dyssynchrony. A traditional CRT device has pacing leads implanted within the right atrium (RA), the right ventricle (RV), and within a coronary vein overlying the lateral or posterior left ventricle (LV). Within the past decade, various multi-center randomized controlled... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
06/08/2022
Locations: Minneapolis Heart Institute (Abbott Northwestern Hospital), Minneapolis, Minnesota
Conditions: Heart Failure, Systolic
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Influence of Pulse Electromagnetic Field Therapy on Myocardial Ischemia
NCT05111288
Recruiting
This study is being done to observe the effects of treatment from a device called the Bioboosti which utilizes pulsed electromagnetic waves on its ability to improve blood flow to the heart tissue in individuals with coronary artery disease (CAD).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/25/2022
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Coronary Artery Disease, Myocardial Infarction
Register for Updates
Optune Delivered Electric Field Therapy and Bevacizumab in Treating Patients With Recurrent or Progressive Grade 2 or 3 Meningioma
NCT02847559
Recruiting
The purpose of this research study is to determine the effects bevacizumab (the study drug) combined with Optune (the study device) tumor treatment field therapy has on meningiomas. Bevacizumab is considered investigational because the US Food and Drug Administration (FDA) has not approved its use for the treatment of meningiomas. The study drug is a medication that blocks the growth of new blood vessels. It is thought that the study drug may interfere with the growth of new blood vessels and th... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/25/2022
Locations: Regions Hospital - Cancer Care Center, Saint Paul, Minnesota
Conditions: Anaplastic (Malignant) Meningioma, Atypical Meningioma, Grade II Meningioma, Grade III Meningioma, Recurrent Meningioma, Supratentorial Meningioma
Register for Updates
Struvite Stones Antibiotic Study
NCT02375295
Recruiting
The aim of this research is to determine an effective antibiotic regimen following definitive surgical therapy of kidney stones caused by bacterial infection (struvite stones).
Gender:
All
Ages:
19 years and above
Trial Updated:
05/16/2022
Locations: Mayo Clinic - Rochester, MN, Rochester, Minnesota
Conditions: Kidney Stones
Register for Updates
Prostate Imaging Using MRI +/- Contrast Enhancement
NCT04571840
Recruiting
This prospective clinical trial (PRostate Imaging using Mri +/- contrast Enhancement (PRIME)) aims to assess whether biparametric MRI (bpMRI) is non-inferior to multiparametric mpMRI (mpMRI) in the detection of clinically significant prostate cancer. This means that we are comparing MRI scans that requires injection of IV contrast (the current standard practice) versus MRI scans that can be performed without IV contrast in the detection of prostate cancer.
Gender:
Male
Ages:
18 years and above
Trial Updated:
05/11/2022
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Prostate Cancer
Register for Updates
Study of ISB 1342, a CD38/CD3 Bispecific Antibody, in Subjects With Previously Treated Multiple Myeloma
NCT03309111
Recruiting
The purpose of this study is to assess safety, efficacy, pharmacokinetic (PK)/pharmacodynamic (PD), and immunogenicity with ISB 1342 in subjects with relapsed/refractory multiple myeloma.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2022
Locations: Mayo Clinic Cancer Center (MCCC) - Rochester, Rochester, Minnesota
Conditions: Relapsed/Refractory Multiple Myeloma
Register for Updates
The Role of Electrophysiology Testing in Survivors of Unexplained Cardiac Arrest
NCT03079414
Recruiting
Sudden cardiac death (SCD) remains a major cause of mortality within developed nations despite aggressive efforts to reduce its societal burden. Despite extensive clinical and genetic investigations, a subgroup of cardiac arrests remain unexplained, highlighting the potential contribution of additional cardiac conditions that may not be identified with contemporary diagnostic algorithms. The EPS ARREST study aims to evaluate the role of invasive electrophysiology study within this patient popula... Read More
Gender:
All
Ages:
All
Trial Updated:
04/29/2022
Locations: Regions Hospital, Saint Paul, Minnesota
Conditions: Sudden Cardiac Death
Register for Updates
Racial and Economic Disparities and Unmet Needs in Patients With Severe Aortic Valvular Disease
NCT04525937
Recruiting
Common barriers to receiving appropriate guideline-driven care for patients with severe aortic stenosis include referral biases by primary care providers (lack of provider education), patient comorbidities (degree of fragility), as well as psychosocial issues and cultural barriers. Additionally, race, ethnicity, socioeconomic status (SES) and education level are shown to be persistent barriers to accessing healthcare services and healthcare systems, creating a significant practice gap between va... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/07/2022
Locations: Minneapolis Heart Institute Foundation, Minneapolis, Minnesota
Conditions: Disparities in Treatment of Aortic Valve Stenosis, Aortic Valve Stenosis
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Real-Time Muscle Pressure Measurements in Patients at Risk for Acute Compartment Syndrome
NCT04671173
Recruiting
The purpose of this trial is to conduct a pilot study that will aid in the design of an evaluation of the clinical benefit of MY01, an FDA cleared device, that allows continuous monitoring of intracompartmental muscle pressure in patients at risk for developing acute compartment syndrome. MY01 has previously been successfully tested on animal and Human cadaver Acute Compartment Syndrome models within the RI MUHC through Department of Defense research Grant (Combat Casualty Care Research Program... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/04/2022
Locations: Hennepin County Medical Center - Orthopaedic Research, Minneapolis, Minnesota
Conditions: Acute Compartment Syndrome
Register for Updates
Genetics of QT Prolongation With Antiarrhythmics
NCT02439658
Recruiting
To assess the ability of common genetic variants in aggregate to predict drug-induced QT prolongation in patients being loaded with dofetilide or sotalol.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/25/2022
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Long QT Syndrome, Drug Toxicity
Register for Updates
Study of Safety and Efficacy of ANG-3070 in Chronic Kidney Disease
NCT04939116
Recruiting
The major objective is to demonstrate the safety and efficacy of ANG-3070 in patients with primary glomerular disease and persistent proteinuria.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/22/2022
Locations: Davita Clinical Research, Edina, Minnesota
Conditions: Glomerular Disease, Proteinuria
Register for Updates