Trajectories of Glomerular Filtration Rate and Progression to End Stage Renal Disease After Kidney Transplantation
NCT04226859
Recruiting
The gold standard for characterizing chronic kidney disease (CKD) is the glomerular filtration rate (GFR), which is commonly estimated in both native and transplanted kidneys for patient monitoring and therapeutic management and ultimately guides decision-making about whether a patient needs renal replacement therapy. In particular, the National Kidney Foundation has defined CKD stages according to estimated GFR (eGFR) values and in several studies, the eGFR slope or change has been found to be... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/13/2020
Locations: William J. von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, Minnesota
Conditions: Kidney Transplant Failure, Kidney Function Issue
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Feasibility Study of the Intravascular Ventricular Assist System (iVAS)
NCT02645539
Recruiting
The purpose of this feasibility study is to assess the preliminary safety and clinical performance of the intravascular ventricular assist system (iVAS).
Gender:
All
Ages:
18 years and above
Trial Updated:
11/11/2019
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Heart Failure NYHA Class III, Heart Failure NYHA Class IV
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Pain Control Following Sinus Surgery
NCT03783702
Recruiting
Given the ongoing national opioid epidemic, an increased interest has developed in optimizing opioid prescribing practices of physicians, including otolaryngologists. Endoscopic sinus surgery (ESS) is one of the most commonly performed surgeries by otolaryngologists with over 250,000 ESS's performed annually in the U.S. Multiple studies have shown that, compared to the amount patients actually consume, otolaryngologists prescribe a high quantity of opioids to patients recovering from ESS). It ha... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/18/2019
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Sinusitis, Opioid Use, Opioid Abuse, Narcotic Use, Otolaryngologic Disease, Postoperative Pain, Pain
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Study of the Safety and Efficacy of OMS721 in Patients With Immunoglobulin A (IgA) Nephropathy
NCT03608033
Recruiting
The purpose of this study is to evaluate the safety and efficacy of OMS721 in patients with IgA nephropathy. The study will assess proteinuria by 24-hour urine protein excretion (UPE) in g/day at 36 weeks from beginning of treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/28/2019
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: IgA Nephropathy
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EndovascuLar RegIstry Evaluating SafeTy, Efficacy and Patient Comfort (ELITE)
NCT03412942
Recruiting
A single-center, prospective, cohort analysis of the Femoral Introducer Sheath and Hemostasis (FISH) vascular closure device will study 100 consecutive patients on which the device will be used to close the femoral artery after angiogram and/or endovascular procedure. Study will be conducted in order to establish the level of comfort and confidence that this device provides for both patients and physician in terms of hemodynamic and usage outcomes.
Gender:
All
Ages:
All
Trial Updated:
08/16/2018
Locations: North Memorial, Robbinsdale, Minnesota
Conditions: Vascular Diseases
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Telescope Exchange Study
NCT03011554
Recruiting
VisionCare's Implantable Miniature Telescope (IMT, intraocular telescope or telescope) is indicated for monocular implantation to improve vision in eyes of patients at least 65 years of age with severe to profound vision impairment caused by bilateral central scotomas associated with end-stage age-related macular degeneration (AMD). Patients with end-stage AMD who have undergone bilateral cataract removal and intraocular lens placement are currently contraindicated for telescope surgery. These... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
04/25/2018
Locations: Minnesota Eye Consultants, Minnetonka, Minnesota
Conditions: Age-related Macular Degeneration
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HealthEast Community Hip and Knee Replacement Registry
NCT02692092
Recruiting
HealthEast Care System began the first community-based joint replacement registry (HJRR) in the U.S. in 1991, and now has more than 30,000 total joints registered. The purpose of the HJRR is to maintain and improve the care of individuals undergoing joint replacement surgery by providing timely information to their surgeons and the broader orthopaedic community. As it moves into the third decade, the HJRR is proud of its role in the development of the national American Joint Replacement Registr... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/23/2018
Locations: HealthEast Care System, Saint Paul, Minnesota
Conditions: Bone Fracture
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Screening for Liver Cancer With CT vs. Ultrasound in Patients With Advanced Liver Disease
NCT01350167
Recruiting
The purpose of this study is to determine whether ultrasound or CT scanning is more effective at detecting early liver cancer in patients with advanced liver disease.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/23/2011
Locations: Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota
Conditions: Cirrhosis, End Stage Liver Disease, Hepatitis C
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