New Jersey is currently home to 1712 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Brunswick, Hackensack, Newark and Morristown. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration
NCT04071457
Recruiting
Patients are enrolled to screening (Reg Step 1) prior to or after ASCT but prior to Reg Step 2. Patients are followed until they will begin Maintenance and then registered to Reg Step 2 (first randomization). Patients are randomized between Lenalidomide for 2 years and Lenalidomide + Daratumumab/rHuPH20. After 2 years of Maintenance, MRD is assessed to guide further therapy. MRD-positive patients will continue with the assigned treatment. MRD-negative patients will be further randomized (Reg Ste... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
08/11/2023
Locations: Cooper Hospital University Medical Center, Camden, New Jersey
Conditions: Multiple Myeloma
Register for Updates
Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer
NCT03678025
Recruiting
This phase III trial studies how well standard systemic therapy with or without definitive treatment (prostate removal surgery or radiation therapy) works in treating participants with prostate cancer that has spread to other places in the body. Addition of prostate removal surgery or radiation therapy to standard systemic therapy for prostate cancer may lower the chance of the cancer growing or spreading.
Gender:
Male
Ages:
18 years and above
Trial Updated:
08/11/2023
Locations: Hackensack University Medical Center, Hackensack, New Jersey
Conditions: Castration Levels of Testosterone, Metastatic Prostatic Adenocarcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8
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IVIG vs SCIG in CIDP
NCT05584631
Recruiting
Current dosing practices for immunoglobulin G (IgG) may be inadequate in extreme body weight. The current study will evaluate the influence of body composition on intravenous and subcutaneous administration of immunoglobulin G in patients.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
08/10/2023
Locations: Rutgers, The State University of New Jersey Clinical Research Center, New Brunswick, New Jersey
Conditions: CIDP, Immunoglobulin Deficiency, Chronic Inflammatory Demyelinating Polyneuropathy
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Renal Denervation + PVI vs PVI Alone for Persistent AF
NCT05116384
Recruiting
Pulmonary vein isolation (PVI) is the cornerstone of ablation for atrial fibrillation (AF). Increased cardiac sympathetic stimulation can facilitate AF and reduction can be accomplished by renal artery denervation (RDN). The recently completed randomized trial, ERADICATE-AF, convincingly demonstrated that RDN plus PVI resulted in a reduction in recurrent incident AF for uncontrolled hypertensives. This is a randomized controlled pilot trial, "To Evaluate Renal Artery Denervation in Addition to... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/10/2023
Locations: University of Rochester, Short Hills, New Jersey
Conditions: Atrial Fibrillation
Register for Updates
Alleviating Geriatric Inpatients' Medication-related Iatrogenesis
NCT05017948
Recruiting
This study will evaluate the MedWise Risk Score™ (MWRS™), a holistic approach to quantifying the risk of a patient's medication regimen. High risk patients will be identified at hospital discharge. Targeted interventions will be made to reduce their MWRS™ with a 30-day follow up. The hypothesis being tested is that a reduction in MWRS™ will lead to reduced 30-day readmission.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
08/10/2023
Locations: Robert Wood Johnson University Hospital Somerset, Somerville, New Jersey
Conditions: Iatrogenic Disease, Risk Reduction
Register for Updates
Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy
NCT01429389
Recruiting
The specimen collection is designed for the purpose of the development of a noninvasive prenatal test for T21.
Gender:
Female
Ages:
18 years and above
Trial Updated:
08/07/2023
Locations: The Cooper Health System, Camden, New Jersey
Conditions: Down Syndrome, Fetal Aneuploidy
Register for Updates
A Study of Using Social Networks to Encourage Three Peers to Complete Screening for Colorectal Cancer
NCT05793593
Recruiting
The Black community has higher rates of colorectal cancer and lower rates of colorectal cancer screenings than whites. Getting screened through FIT testing may help catch colorectal cancer earlier, when it is easier to treat. MSK has created a program to help people who have been FIT tested to also help their peers (family, friends, and colleagues) in their community get FIT tested. The researchers think that training people on peer outreach, such as telling people in your social network about F... Read More
Gender:
Male
Ages:
Between 45 years and 75 years
Trial Updated:
08/03/2023
Locations: Memoiral Sloan Kettering Basking Ridge (All Protocol Activities), Basking Ridge, New Jersey
Conditions: Colon Cancer Screening
Register for Updates
Values and Options in Cancer Care 2 (VOICE 2) A Randomized Pilot Study
NCT05352451
Recruiting
Primary Objective: Aim 1: To evaluate the acceptability and feasibility of recruitment strategies for subjects for VOICE 2 intervention. Secondary Objective: Aim 2: To test the preliminary efficacy of VOICE 2 on oncologist-patient, patient-caregiver, and oncologist-caregiver concordant prognostic understanding, oncologist-patient and oncologist-caregiver therapeutic alliance, patient/caregiver depression/anxiety and death anxiety, and patient/caregiver meaning/purpose.
Gender:
All
Ages:
21 years and above
Trial Updated:
08/03/2023
Locations: Rutgers Cancer Institute of New Jersey-University Hospital, New Brunswick, New Jersey
Conditions: Communication, Multidisciplinary
Register for Updates
Visual Acoustic Biofeedback for RSE Via Telepractice
NCT04858022
Recruiting
This research will meet a public health need by evaluating the efficacy of speech intervention supplemented with real-time visual-acoustic biofeedback when delivered using remote technologies.
Gender:
All
Ages:
Between 9 years and 15 years
Trial Updated:
08/03/2023
Locations: Montclair State University, Upper Montclair, New Jersey
Conditions: Speech Sound Disorder
Register for Updates
Loratadine for the Reduction of G-CSF Induced Bone Pain in Patients With Multiple Myeloma Undergoing Stem Cell Mobilization
NCT04211259
Recruiting
This early phase I trial studies how well loratadine works in reducing granulocyte-colony stimulating factor (G-CSF) induced bone pain in patients with multiple myeloma who are undergoing stem cell mobilization. Loratadine is an antihistamine that may help to reduce or control bone pain during the process of stem cell collection in patients with multiple myeloma.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/03/2023
Locations: Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
Conditions: Plasma Cell Myeloma
Register for Updates
Targeted Genomic Analysis of Blood and Tissue Samples From Patients With Cancer
NCT02688517
Recruiting
This research trial studies the use of targeted genomic analysis of blood and tissue samples from patients with cancer. Genomic sequencing is a laboratory method that is used to determine the entire genetic makeup of a specific organism or cell type. Genomic sequencing can be used to find changes in areas of the genome that may be important in the development of cancer. It may also help doctors improve ways to diagnose and treat patients with rare cancers with poor prognosis or lack of effective... Read More
Gender:
All
Ages:
1 year and above
Trial Updated:
08/03/2023
Locations: Ocean Medical Center, Brick, New Jersey
Conditions: Malignant Neoplasm
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A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors
NCT05985161
Recruiting
The purpose of this study is to find out whether selinexor is an effective treatment for people under the age of 51 who have a relapsed/refractory Wilms tumor, rhabdoid tumor, MPNST, or another solid tumor that makes a higher than normal amount of XPO1 or has genetic changes that increase the activity of XP01.
Gender:
All
Ages:
12 months and above
Trial Updated:
08/02/2023
Locations: Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities), Basking Ridge, New Jersey
Conditions: Wilms Tumor, Rhabdoid Tumor, Malignant Peripheral Nerve Sheath Tumors, MPNST, Nephroblastoma, XPO1 Gene Mutation, Solid Tumor
Register for Updates