New Jersey is currently home to 1712 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Brunswick, Hackensack, Newark and Morristown. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Safety, PK, PD, Clinical Activity of KT-333 in Adult Patients With Refractory Lymphoma, Large Granular Lymphocytic Leukemia, Solid Tumors
NCT05225584
Recruiting
This Phase 1a/1b study will evaluate the safety, tolerability and the pharmacokinetics/pharmacodynamics (PK/PD) of KT-333 in Adult patients with Relapsed or Refractory (R/R) Lymphomas, Large Granular Lymphocytic Leukemia (LGL-L), T-cell prolymphocytic leukemia (T-PLL), and Solid Tumors. The Phase 1a stage of the study will explore escalating doses of single-agent KT-333. The Phase Ib stage will consist of 4 expansion cohorts to further characterize the safety, tolerability and the pharmacokineti... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/02/2023
Locations: Hackensack University Medical Center, John Theurer Cancer Center, Hackensack, New Jersey
Conditions: Non Hodgkin Lymphoma (NHL), Peripheral T-cell Lymphoma (PTCL), Cutaneous T-Cell Lymphoma (CTCL), Large Granular Lymphocytic Leukemia (LGL-L), Solid Tumors, T-cell Prolymphocytic Leukemia (T-PLL)
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Study of RP1 Monotherapy and RP1 in Combination With Nivolumab
NCT03767348
Recruiting
RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects with advanced and/or refractory solid tumors, to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D), as well as to evaluate preliminary efficacy.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/01/2023
Locations: Atlantic Health System, Morristown, New Jersey
Conditions: Cancer, Melanoma (Skin), Mismatch Repair Deficiency, Microsatellite Instability, Non-melanoma Skin Cancer, Cutaneous Melanoma, NSCLC
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Lymphatic System Stimulation in Heart Failure
NCT05834400
Recruiting
The goal of this pilot clinical trial is to obtain preliminary data on the effects of lymphatic exercise training in patients with heart failure. The main question[s] it aims to answer are: Does performing lymphatic exercise decrease fluid overload symptoms (shortness of breath, lower legs swelling, fatigue), thoracic fluid content, and body fluid level? Does performing lymphatic exercise improve sleep and quality of life (QOL)? Participants with heart failure will be randomly assigned into tw... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
07/31/2023
Locations: Cooper University Health Care (Cooper), Camden, New Jersey
Conditions: Heart Failure
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Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer
NCT03186898
Recruiting
This phase III trial studies how well radiation therapy with protons works compared with photons in treating patients with liver cancer. Radiation therapy, such as photon therapy, uses high energy x-rays to send the radiation inside the body to the tumor while proton therapy uses a beam of proton particles. Proton therapy can stop shortly after penetrating through the tumor and may cause less damage to the surrounding healthy organs and result in better survival in patients with liver cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/31/2023
Locations: Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey
Conditions: Unrectable or Locally Recurrent Hepatocellular Carcinoma
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Groningen International Study on Sentinel Nodes in Vulvar Cancer-III
NCT05076942
Recruiting
Vulvar cancer patients with SN-metastasis > 2mm will receive chemoradiation instead of an inguinofemoral lymphadenectomy.
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/27/2023
Locations: Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey
Conditions: Vulvar Cancer, Sentinel Lymph Node, Lymph Node Metastases
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Novel Biochemical and Molecular Determinants for Soft Tissue Sarcoma
NCT00579566
Recruiting
The purpose of this study is to study normal and sarcoma cells. To study these cells we need to have human tissue. You will be having or have already had a procedure to remove tissue. We would like to use some of this tissue. We will use it for laboratory studies on the diagnosis,behavior and treatment of sarcoma. We will perform an extensive analysis of your samples. We will only use extra tissue left over after all needed testing has been done or remove an additional small amount of tissue if... Read More
Gender:
All
Ages:
All
Trial Updated:
07/27/2023
Locations: Memorial Sloan Kettering Basking Ridge (Consent and Follow-Up), Basking Ridge, New Jersey
Conditions: Sarcoma
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Accuracy of Pediatric Emergency Medicine Providers in Diagnosing Hip Effusions Using Point of Care Ultrasound
NCT05971745
Recruiting
The purpose of this study is to determine if pediatric emergency medicine providers can accurately diagnose a hip effusion using point-of-care ultrasound (POCUS) compared to radiology ultrasound (RADUS).
Gender:
All
Ages:
Between 1 month and 18 years
Trial Updated:
07/25/2023
Locations: Newark Beth Israel Medical Center, Newark, New Jersey
Conditions: Hip Effusion, Septic Arthritis, Transient Synovitis, Hip
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Safety and Efficacy of Corneal Cross-linking in Subjects With Keratoconus
NCT05314738
Recruiting
Clinical Trial to Evaluate the Safety and Efficacy of Corneal Cross-linking in Subjects with Keratoconus.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
07/25/2023
Locations: Glaukos Investigative Site, Teaneck, New Jersey
Conditions: Progressive Keratoconus
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Collection of Sputum and Labeling for Lung Cancer
NCT03457415
Recruiting
The primary objective of this study is to compare Assay results to diagnoses determined by currently accepted standards for lung cancer detection. This will be accomplished by analysis of sputum samples from three cohorts including healthy Participants, high risk Participants, and cancer patient Participants using the Assay as developed in accordance with findings of bioAffinity protocol BA-001 to confirm assay results. Adjustments will be made as necessary to finalize Assay design for clinical... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
07/25/2023
Locations: Summit Medical Group, Berkeley Heights, New Jersey
Conditions: Lung Cancer
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Internet Assisted Career-Oriented Soft-skills Training for Transition Age Youth With Mental Health Conditions
NCT05766280
Recruiting
The purpose of this study is to evaluate the effectiveness of an internet- assisted Career-Oriented Work-Related Soft-skills Training (iCareer) intervention, infused with cognitive behavioral therapy, targeting individuals ages 16-24 with mental health conditions, to improve employment outcomes. The overall objective is to help transition-age youth (TAY) with psychiatric disabilities achieve optimal employment outcomes as part of successful transition to adulthood. Findings will have implication... Read More
Gender:
All
Ages:
Between 16 years and 24 years
Trial Updated:
07/22/2023
Locations: Rutgers Univeristy, Newark- Office of Disability Services, Newark, New Jersey
Conditions: Mental Health Wellness 1, Mental Health Wellness 2, Occupational Problems
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Absorbable Suture vs Permanent Suture in Sacrospinous Ligament Suspension
NCT05688059
Recruiting
Sacrospinous ligament suspension (SSLS) was first described in 1958. It is commonly performed for correction of apical prolapse. A combination of delayed absorbable and/or permanent sutures are commonly used for the procedure. When permanent sutures are used, risk of suture-related complications is present and patients may require suture removal. In available literature, there is limited data comparing the efficacy and suture-related complications when using different types of sutures. A previou... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/20/2023
Locations: Atlantic Health System, Morristown, New Jersey
Conditions: Pelvic Organ Prolapse, Uterovaginal Prolapse, Vaginal Vault Prolapse, Cystocele
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Lysosomal Acid Lipase (LAL) Deficiency Registry
NCT01633489
Recruiting
This is an observational, multi-center, international disease registry designed to collect longitudinal data and create a knowledge base that will be utilized to improve the care and treatment of patients with LAL Deficiency. Participation in the Registry by both physicians and patients is voluntary.
Gender:
All
Ages:
All
Trial Updated:
07/20/2023
Locations: Not set, Hackensack, New Jersey
Conditions: Lysosomal Acid Lipase Deficiency, Cholesterol Ester Storage Disease, Wolman Disease, Acid Cholesteryl Ester Hydrolase Deficiency, Type 2, Acid Lipase Deficiency, LIPA Deficiency, LAL-Deficiency
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