New Jersey is currently home to 1677 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Brunswick, Hackensack, Newark and Morristown. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Study of DF9001 in Patients With Advanced Solid Tumors
NCT05597839
Recruiting
DF9001-001 is a study of a new molecule that targets natural killer (NK) cells and T-cell activation signals to specific receptors on cancer cells. The study will occur in two phases. The first phase will be a dose escalation phase, enrolling patients with various types of solid tumors that express epidermal growth factor receptor (EGFR). The second phase will include a dose expansion using the best dose selected from the first phase of the study. Multiple cohorts will be opened with eligible pa... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Rutgers, New Brunswick, New Jersey
Conditions: Solid Tumor, Adult
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A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children
NCT05543616
Recruiting
The purpose of this clinical trial is to learn about the safety, extent of the side effects, and immune responses of the study vaccine (called variant-adapted BNT162b2 RNA-based vaccine) in healthy children. The trial is divided into 5 individual studies or substudies based on age group and prior history of COVID-19 vaccinations. All participants in each of the 5 sub-studies will receive study vaccine as a shot depending on what group they are in. * Substudy A design: Phase 1 includes participa... Read More
Gender:
ALL
Ages:
Between 6 months and 11 years
Trial Updated:
05/13/2024
Locations: Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey
Conditions: SARS-CoV-2 Virus, Severe Acute Respiratory Syndrome Coronavirus 2, COVID-19
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PARTNER 3 Trial - Aortic Valve-in-Valve
NCT03003299
Recruiting
This study will assess the safety and effectiveness of the SAPIEN 3/SAPIEN 3 Ultra transcatheter heart valve (THV) in patients with a failing aortic bioprosthetic valve.
Gender:
ALL
Ages:
All
Trial Updated:
05/08/2024
Locations: Newark Beth Israel, Newark, New Jersey
Conditions: Aortic Stenosis, Aortic Stenosis, Severe
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Clinical Application of Stem Cell Educator Therapy in Type 1 Diabetes
NCT04011020
Recruiting
Type 1 diabetes (T1D) is a T cell-mediated autoimmune disease that causes a deficit of pancreatic islet beta cells. Millions of individuals worldwide have T1D, and incidence increases annually. Several recent clinical trials point to the need for an approach that produces comprehensive immune modulation at both the local pancreatic and systemic levels. Stem Cell Educator (SCE) therapy offers comprehensive immune modulation at both the local and systemic levels in T1D by using a patient's own imm... Read More
Gender:
ALL
Ages:
14 years and above
Trial Updated:
04/25/2024
Locations: Hackensack Meridian Health, Hackensack, New Jersey
Conditions: Type 1 Diabetes
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Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2
NCT05555589
Recruiting
The objective of this study is to compare the safety and efficacy of RGN-259 to placebo for the treatment of Neurotrophic Keratopathy (NK)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: Atlantic Eye, Eatontown, New Jersey
Conditions: Neurotrophic Keratopathy
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The Effect of Sulfasalazine on CRH Levels in Pregnant Women
NCT05703425
Recruiting
The goal of this randomized clinical trial is to assess sulfasalazine as a potential treatment to prevent recurrent preterm birth. The main questions it aims to answer are: * Does sulfasalazine down regulate corticotropin releasing hormone (CRH) levels in pregnant persons with a prior history of preterm birth? * Does sulfasalazine reduce the incidence of recurrent preterm birth in pregnant persons given drug vs. controls? Consenting participants will be randomized to receive sulfasalazine or t... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/15/2024
Locations: Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey
Conditions: Preterm Birth
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Effectiveness of Virtual Reality Vision Therapy - VERVE
NCT04691427
Recruiting
The purpose of this research study is to see how well the treatment of a participant's eye coordination and/or focusing problems improves eye muscle responses and symptoms of eyestrain. We will use an entertainment device called a virtual reality headset to play a custom-designed video game to find out how well the treatment of binocular vision improves a participant's coordination and/or focusing problem. The virtual reality headset uses eye-trackers to monitor progress in a totally objective m... Read More
Gender:
ALL
Ages:
Between 9 years and 35 years
Trial Updated:
04/15/2024
Locations: OculoMotor Technologies, Newark, New Jersey
Conditions: Convergence Insufficiency
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The Utilization Effects of Powered Wearable Orthotics in Improving Upper Extremity Function and ADL in Persons With SCI
NCT06349434
Recruiting
To evaluate the usefulness of an upper extremity assistive device, called (MyoPro) in improving upper extremity activities in people with incomplete spinal cord injury. The Department of Defense is supporting this study.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
04/11/2024
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: SCI - Spinal Cord Injury, Upper Extremity Dysfunction, Upper Extremity Problem
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ATATcH Alternating Treatment Plans for Advanced Cancer
NCT05358548
Recruiting
The purpose of the research is to evaluate a new schedule of alternating cycles of induction chemoimmunotherapy (chemotherapy plus pembrolizumab) and immunotherapy (pembrolizumab) alone for the initial treatment of patients with advanced lung or head and neck cancers.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/09/2024
Locations: Trinitas Hospital and Comprehensive Cancer Center, Elizabeth, New Jersey
Conditions: Head and Neck Cancer, Lung Cancer
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Investigating Targetable Metabolic Pathways Sustaining Pancreatic Cancer
NCT05296421
Recruiting
This clinical trial investigates the nutrients pancreatic cancers depend on in which to survive and the processes these tumors use (metabolism) to obtain these nutrients. Giving U-13C-glucose during surgery may allow doctors to trace the metabolic activity of pancreatic cancer in research experiments done in the laboratory. These experiments may help researchers understand how cancer cells manage their nutrients when compared to normal pancreatic cells.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/09/2024
Locations: Cooperman Barnabas Medical Center (Saint Barnabas Medical Center), Livingston, New Jersey
Conditions: Pancreatic Ductal Adenocarcinoma
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mHealth Mindfulness With Patients With Serious Illness and Their Caregivers
NCT05040711
Recruiting
Older adults with serious illness and their caregivers have high rates of anxiety and limited access to effective, non-pharmacological treatments. A recent National Academy of Medicine report recommended increased emphasis on disseminating and implementing evidence-based psychotherapies in order to have maximal public health impact. Through this work, I will identify a sustainable and potentially scalable dyadic intervention and delivery model to manage symptoms of anxiety in older adults with s... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
04/09/2024
Locations: RWJ Barnabas Outpatient Geriatric Clinics, Livingston, New Jersey
Conditions: Caregiver Stress Syndrome, Anxiety
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Refinements of Functional Communication Training
NCT04045600
Recruiting
Although treatments for problem behavior, like functional communication training (FCT), can be highly effective in the clinic, changes in the way the FCT is implemented (e.g., when transferring treatment to the home, when teachers implement treatment with poor fidelity) can result in treatment relapse. The goal of this study is to evaluate whether using treatment signals and gradually introducing materials from natural contexts can help mitigate treatment relapse during context changes and poor... Read More
Gender:
ALL
Ages:
Between 3 years and 17 years
Trial Updated:
04/08/2024
Locations: Children's Specialized Hospital - Rutgers University Center for Autism Research, Education, and Services, Somerset, New Jersey
Conditions: Aggression, Self-injurious Behavior
Register for Updates