New Jersey is currently home to 1654 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Brunswick, Hackensack, Newark and Morristown. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Safety and Tolerability of KH631 Gene Therapy in Participants With Neovascular Age-related Macular Degeneration
NCT05657301
Recruiting
VAN-2201 is Phase I clinical trial to assess the safety and tolerability of KH631 in subjects with neovascular AMD. KH631 is gene therapy designed to deliver a protein which targets and blocks VEGF via an adeno-associated viral vector. The standard of care for patients with neovascular AMD are anti-VEGF treaments, which have demonstrated improvement in vision and reduction in fluid. A one time placement of a product which inhibits VEGF has the potential to reduce the patient burden of regular in... Read More
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
02/23/2024
Locations: Kanghong Investigative Site, Cherry Hill, New Jersey
Conditions: Age-Related Macular Degeneration
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Cardiogenic Shock Working Group Registry
NCT04682483
Recruiting
The Cardiogenic Shock Working Group is a multicenter registry where we collect de-identified clinical variables from the medical records and follow-up phone calls of shock patients from multiple institutions and centralize this data to a single registry for analysis of clinical outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/21/2024
Locations: Hackensack Meridian Health, Hackensack, New Jersey
Conditions: Cardiogenic Shock
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Comparing Hypothermic Temperatures During Hemiarch Surgery
NCT02860364
Recruiting
Hypothermic circulatory arrest is an important surgical technique, allowing complex aortic surgeries to be performed safely. Hypothermic circulatory arrest provides protection to cerebral and visceral organs, but may result in longer cardiopulmonary bypass times during surgery, increased risks of bleeding, inflammation, and neuronal injury. To manage these consequences, a trend towards warmer core body temperatures during circulatory arrest has emerged. This trial will randomize patients to eith... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/21/2024
Locations: The Valley Hospital, Ridgewood, New Jersey
Conditions: Thoracic Aortic Disease
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A Study to Investigate Leramistat in Patients With IPF
NCT05951296
Recruiting
To compare the effect of daily oral dosing of leramistat over 12 weeks with placebo in participants aged 40 years or older with idiopathic pulmonary fibrosis (IPF).
Gender:
ALL
Ages:
40 years and above
Trial Updated:
02/16/2024
Locations: Hudson County Clinical Trials Research Center, Union City, New Jersey
Conditions: Idiopathic Pulmonary Fibrosis
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ELUCIDATE FFRct Study
NCT06018194
Recruiting
The goal of this study is to evaluate the diagnostic accuracy of a novel plaque-based coronary CT angiography (CCTA) fractional flow reserve (FFRct) software device for the estimation of invasive fractional flow reserve (FFR). Researchers will compare the Elucid plaque-based FFRct analysis to invasively measured FFR in patients who have previously undergone CCTA and invasively assessed FFR.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/15/2024
Locations: Valley Health System, Ridgewood, New Jersey
Conditions: Coronary Artery Disease
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A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH
NCT04764474
Recruiting
An open label single-arm clinical trial to evaluate the safety, tolerability, PK, PD, and preliminary efficacy of HMPL-306 in subjects with advanced relapsed, refractory, or resistant hematological malignancies that harbor IDH mutations.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/13/2024
Locations: Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
Conditions: Isocitrate Dehydrogenase Gene Mutation
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Examining Effects of Tysabri on Cognitive Fatigue Using fMRI
NCT04565431
Recruiting
The purpose of this research study is to investigate the effectiveness of Tysabri on cognitive fatigue in persons with Relapsing-Remitting Multiple Sclerosis (RRMS). Cognitive fatigue is the kind of fatigue that occurs after intense mental concentration as after a session of problem solving.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
02/13/2024
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Multiple Sclerosis, Relapsing-Remitting
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Examining Effects of Ocrevus on Cognitive Fatigue Using fMRI
NCT04448977
Recruiting
The purpose of this research study is to investigate the effectiveness of MS Disease modifying medications on cognitive fatigue in persons with relapsing remitting multiple sclerosis (RRMS). Cognitive fatigue is the kind of fatigue that occurs after intense mental concentration as after a session of problem solving.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
02/13/2024
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Multiple Sclerosis, Relapsing-Remitting
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The Effectiveness of Prophylactic Antibiotics for Urethral Bulking
NCT06261736
Recruiting
The goal of this clinical trial is to evaluate if prophylactic antibiotics in urethral bulking are effective in reducing postprocedural urinary tract infections.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
02/08/2024
Locations: Atlantic Health, Morristown, New Jersey
Conditions: Stress Urinary Incontinence, Postoperative Urinary Tract Infection, Urethral Bulking
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Phrenic Nerve Reconstruction for the Treatment of Diaphragmatic Paralysis: Patient Experiences and Reported Outcomes.
NCT06243718
Recruiting
This study utilizes a grounded theory methodology to explore patient experiences of phrenic nerve reconstructive surgery as a treatment for diaphragmatic paralysis.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
02/05/2024
Locations: Advanced Reconstructive Surgery Alliance, Red Bank, New Jersey
Conditions: Diaphragmatic Paralysis, Pain, Chest, Breath Shortness
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The Acute Burn ResUscitation Multicenter Prospective Trial
NCT04356859
Recruiting
This is a prospective randomized multi-center study which will compare acute fluid resuscitation using a colloid strategy (LR + 5% Albumin) to a crystalloid strategy (LR alone), in adults with an acute burn involving at least 25% of their total body surface area.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2024
Locations: Cooperman Barnabas Medical Center, Livingston, New Jersey
Conditions: Burn Injury
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Observational Study of the Safety of Intravenous Artesunate Treatment of Pregnant Women and Their Infants
NCT05285735
Recruiting
This study is a prospective observational study in which a female patient who received IV Artesunate while pregnant can volunteer to provide information about her pregnancy and the outcome of her pregnancy. Information will be collected from patient's provider, the patient's obstetrician, the child's pediatrician, or other relevant healthcare provider.
Gender:
FEMALE
Ages:
Between 15 years and 100 years
Trial Updated:
01/29/2024
Locations: 4C Pharma Solutions, Piscataway, New Jersey
Conditions: Pregnancy, Malaria
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