New Jersey is currently home to 1681 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Brunswick, Hackensack, Newark and Morristown. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Behavioral Exposure for Introceptive Tolerance RCT
NCT05398276
Recruiting
Behavioral Exposure for Interoceptive Tolerance (BE-FIT) is a mechanism-informed behavioral intervention to target exercise anxiety. The three primary components of BE-FIT include: (1) exposure to feared bodily sensations and exercise; (2) prevention of safety behavior use before/during/after exercise, and (3) use of a wrist-worn activity monitor for physical activity (PA) feedback and activity goal setting. Evidence from the investigators' Stage I trial indicated that BE-FIT is feasible, accept... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
03/25/2024
Locations: RWJ Cardiac Rehab at East Brunswick, East Brunswick, New Jersey
Conditions: Exercise Sensitivity, Introceptive Exposure, Anxiety, Cardiac Rehabilitation
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Treatment With Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI
NCT05180032
Recruiting
The objective of the proposed work is to determine whether administration for 12 months of romosozumab (evenity) followed by 12 months of denosumab (prolia) will maintain bone mass at the knee in subjects with chronic SCI.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/21/2024
Locations: Kessler Institute for Rehabilitation, West Orange, New Jersey
Conditions: Osteoporosis, Spinal Cord Injuries
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Modulating Reward Learning Using Transcranial Magnetic Stimulation
NCT06323057
Recruiting
Our specific aim is to examine the effects of TMS on reward processing during goal-directed behavior. In these experiments the investigators will utilize a scalp-recorded brain oscillation called frontal midline theta that is believed to index the sensitivity of the cingulate cortex to reward feedback. Here the investigators will asked whether this electrophysiological signal can be modulated up or down using TMS while participants engage in decision making tasks, and if so, whether it would aff... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
03/20/2024
Locations: Rutgers University - Newark, Newark, New Jersey
Conditions: Behavior
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Sequential TAS-OX Alternating With TAS-IRI Plus Bevacizumab for Late-Line Metastatic Colorectal Cancer
NCT05806931
Recruiting
This study is to evaluate the disease control rate and time to progression of the sequential combination of oxaliplatin with an alternative anti-metabolite Trifluridine/tipiracil hydrochloride mixture, TAS-102,(TAS-OX) as well as irinotecan in combination with TAS-102 oxaliplatin(TAS-OX) + Bevacizumab in late-line metastatic colorectal cancer (mCRC)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: Trinitas Hospital and Comprehensive Cancer Center, Elizabeth, New Jersey
Conditions: Colon Cancer, Rectal Cancer
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Microbiotic Product to Promote Microbiome Health and Improve Chemotherapy Delivery
NCT05296681
Recruiting
This phase II trial tests whether NBT-NM108 works in reducing chemotherapy-induced diarrhea in patients with colon cancer that has spread to other places in the body (metastatic). Irinotecan is one of the most used medicine for colon cancer, but it leads to diarrhea in most patients receiving it and among some of them, severe diarrhea can occur. NBT-NM108 is a high dietary fiber formula that is developed based on research findings that have shown that high fiber diets can help maintain healthy b... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: Robert Wood Johnson University Hospital, Hamilton, Hamilton, New Jersey
Conditions: Metastatic Colon Carcinoma, Stage IV Colon Cancer AJCC v8, Stage IVA Colon Cancer AJCC v8, Stage IVB Colon Cancer AJCC v8, Stage IVC Colon Cancer AJCC v8
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Peritoneal Carcinomatosis Leveraging ctDNA Guided Treatment in GI Cancer Study (PERICLES Study)
NCT04929015
Recruiting
This clinical trial collects biospecimen samples to create a personalized ctDNA test to guide treatment for patients with gastrointestinal cancer with peritoneal carcinomatosis. Deoxyribonucleic acid, or DNA, is the material that carries all the information about how a living thing will work and function. Everyone is born with the same DNA in all our cells throughout our body. Sometimes, some of the cells in the body develop abnormalities in the DNA that cause those cells to grow abnormally and... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: RWJBarnabas Health - Cooperman Barnabas, Livingston, Livingston, New Jersey
Conditions: Appendix Carcinoma by AJCC V8 Stage, Colorectal Carcinoma by AJCC V8 Stage, Digestive System Neoplasm, Esophageal Carcinoma by AJCC V8 Stage, Gastric Carcinoma by AJCC V8 Stage, Liver and Intrahepatic Bile Duct Carcinoma, Peritoneal Carcinomatosis
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Using Virtual Reality to Improve Job Reentry in Adults With TBI
NCT04820634
Recruiting
The purpose of this research is to investigate the effectiveness of virtual reality (VR) to improve job reentry skills in individuals with TBI.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
03/19/2024
Locations: Kessler Foundation, East Hanover, New Jersey
Conditions: Traumatic Brain Injury
Register for Updates
I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients
NCT04488081
Recruiting
The goal of this project is to rapidly screen promising agents, in the setting of an adaptive platform trial, for treatment of critically ill COVID-19 patients. In this phase 2 platform design, agents will be identified with a signal suggesting a big impact on reducing mortality and the need for, as well as duration, of mechanical ventilation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/15/2024
Locations: Virtua Mount Holly Hospital, Mount Holly, New Jersey
Conditions: COVID-19
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A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)
NCT06322693
Recruiting
This is a first-in-human study evaluating the anti-T cell immunoglobulin and mucin containing protein-3 (TIM-3) antibody TSR-022. The study will be conducted in 2 parts with Part 1 consisting of dose escalation and Part 2 dose expansion. Part 1 will determine the recommended Phase 2 dose (RP2D) of TSR-022 and Part 2 will evaluate the antitumor activity of TSR-022 in combination with TSR-042 or docetaxel and as monotherapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/14/2024
Locations: GSK Investigational Site, Hackensack, New Jersey
Conditions: Neoplasms
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Dupixent and Narrowband UVB for Atopic Dermatitis
NCT05285839
Recruiting
24 weeks open-label study with dupilumab and narrowband UVB phototherapy three times weekly for 12 weeks followed by 12 weeks of dupilumab monotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/14/2024
Locations: Eczema Treatment Center of New Jersey, East Windsor, New Jersey
Conditions: Atopic Dermatitis
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LOWER: Lomitapide Observational Worldwide Evaluation Registry
NCT02135705
Recruiting
This global product exposure registry is a multicentre, long-term, prospective, observational cohort study (exposure registry), designed to evaluate the long term safety and effectiveness of lomitapide.
Gender:
ALL
Ages:
All
Trial Updated:
03/11/2024
Locations: Hackensack Meridian Health, Edison, New Jersey
Conditions: Homozygous Familial Hypercholesterolemia
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Liver Transplantation in Intrahepatic Cholangiocarcinoma
NCT06140134
Recruiting
The aim of the current study is to determine the potential efficacy of liver transplantation in the form of patients' overall survival (OS) after neoadjuvant systemic therapy in patients with biologically responsive locally advanced non-metastatic intrahepatic cholangiocarcinoma (iCCA) in comparison to patients historically treated with chemotherapy alone.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
03/08/2024
Locations: Rutgers New Jersey Medical School, Newark, New Jersey
Conditions: Intrahepatic Cholangiocarcinoma, Cholangiocarcinoma, Intrahepatic
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