New Jersey is currently home to 1712 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Brunswick, Hackensack, Newark and Morristown. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Use of the Impella BTR™ in Patients With Heart Failure: An Early Feasibility Study
NCT05291884
Recruiting
This is a prospective, multi-center, single-arm, early feasibility study that aims to evaluate the safety of the Impella BTR™ in adult patients requiring left-ventricular hemodynamic support, and to evaluate the effectiveness of the Impella BTR™ in supporting patients to recovery or their next therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/07/2023
Locations: Hackensack University Medical Center, Hackensack, New Jersey
Conditions: Heart Failure, Acute Decompensated Heart Failure
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Development of a Virtual Reality Spatial Retraining Therapy to Improve Neglect in Stroke Survivors
NCT04793516
Recruiting
Participants in this study will help test and develop a virtual reality (VR) system that is being designed to help people with spatial neglect after stroke.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/02/2023
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Stroke, Spatial Neglect
Register for Updates
Parkinson Disease and DBS: Cognitive Effects in GBA Mutation Carriers
NCT03234478
Recruiting
Every year, approximately 9,000 Parkinson disease (PD) patients undergo deep brain stimulator (DBS) placement into the subthalamic nucleus (STN-DBS). Studies suggest that PD patients with mutations in the glucocerebrosidase (GBA) gene are at high risk for cognitive impairment and approximately 10-17% of subjects undergoing DBS carry GBA mutations. There may be an interaction between STN-DBS, which also impairs cognitive function, and GBA, resulting in worsened cognitive function. This project wi... Read More
Gender:
All
Ages:
Between 30 years and 75 years
Trial Updated:
06/01/2023
Locations: Rutgers-Robert Wood Johnson Medical School, New Brunswick, New Jersey
Conditions: Parkinson, Parkinson Disease, Genetic Predisposition, GBA Gene Mutation, Cognitive Decline
Register for Updates
RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Diabetic Retinopathy (DR) Without Center Involved-Diabetic Macular Edema (CI-DME)
NCT04567550
Recruiting
RGX-314 is being developed as a novel, potential one-time gene therapy treatment for the treatment of diabetic retinopathy, a chronic and progressive complication of diabetes mellitus. Diabetic retinopathy (DR) is a sight-threatening disease characterized in the early stages by neuronal and vascular dysfunction in the retina, and later by neovascularization that leads to further deterioration of functional vision. Despite the availability of current treatments, diabetic retinopathy remains the l... Read More
Gender:
All
Ages:
Between 25 years and 89 years
Trial Updated:
05/18/2023
Locations: NJ Retina, Teaneck, New Jersey
Conditions: Diabetic Retinopathy (DR)
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Arrythmia Burden in Cardiac Contractility Modulation (CCM)
NCT05704426
Recruiting
The Impulse Dynamics Optimizer Device is a Food and Drug Administration (FDA) approved; commercially available device indicated for patients with heart failure with reduced ejection fraction (HFrEF). Many candidates of this device have a previously implanted cardiovascular implantable electronic device (CIED)- internal cardioverter defibrillator (ICD) or permanent pacemaker (PM). Patients with heart failure are at high risk for both atrial and ventricular cardiac arrhythmias. The aim of this st... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/11/2023
Locations: Hackensack Univeristy Medical Center, Hackensack, New Jersey
Conditions: Atrial Fibrillation, Arrythmia
Register for Updates
Tislelizumab Consolidation After Liver-Directed Therapy for Hepatocellular Carcinoma
NCT05366829
Recruiting
The investigators hypothesize that the addition of Tislelizumab after definitive local therapy for locally advanced inoperable Hepatocellular carcinoma (HCC) will synergize with local therapy as well as treat micro metastatic disease and improve one year progression-free survival rates for participants and optimize local control.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2023
Locations: Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
Conditions: Carcinoma, Hepatocellular, Liver Cell Carcinoma
Register for Updates
GnRH for Luteal Support in IVF/ICSI/FET Cycles
NCT02357654
Recruiting
During IVF cycles an embryo is generally placed into the uterine cavity between 3 and 5 days after fertilization. For a successful pregnancy to take place, that embryo must then implant in the properly primed and staged endometrium, which subsequently must continue to develop to accommodate the growing and maturing embryo and then fetus. This process is normally regulated by hormonal interactions between the fetal, endometrial and luteal tissue. It has been found that after IVF additional suppor... Read More
Gender:
Female
Ages:
Between 18 years and 40 years
Trial Updated:
05/10/2023
Locations: University Reproductive Associates, Hasbrouck Heights, New Jersey
Conditions: Infertility
Register for Updates
Evaluation of Home-based Sensor System to Detect Health Decompensation in Elderly Patients With History of CHF or COPD
NCT05865184
Recruiting
Sensorum Health (Sensorum) is conducting a pilot study to determine if Sensorum's proprietary passive sensor network can be used to identify signals of early health decompensation in subjects prior to a hospitalization for chronic disease exacerbation or other ambulatory care sensitive conditions. Successful early detection would provide a window of opportunity to intervene outside of the acute setting in future interventional studies.
Gender:
All
Ages:
65 years and above
Trial Updated:
05/09/2023
Locations: Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, New Jersey
Conditions: COPD, Chronic Obstructive Pulmonary Disease, COPD Exacerbation, CHF, Congestive Heart Failure
Register for Updates
Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)
NCT05731986
Recruiting
The goal of this clinical trial is to evaluate the effect of transcutaneous spinal cord stimulation on blood pressure in individuals with an acute spinal cord injury (within 30 days of injury). Blood pressure instability, specifically orthostatic hypotension (a drop in blood pressure when moving lying flat on your back to an upright position), appears early after the injury and often significantly interferes with participation in the critical rehabilitation time period. The main questions it ai... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/08/2023
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Spinal Cord Injuries, Spinal Cord Diseases, Trauma, Nervous System, Nervous System Diseases, Central Nervous System Diseases, Hypotension, Orthostatic Hypotension, Cardiovascular Diseases, Acute Spinal Cord Injury, Blood Pressure
Register for Updates
The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)
NCT05725499
Recruiting
This project will investigate the effect of spinal cord transcutaneous stimulation on blood pressure in individuals with a chronic spinal cord injury who experience blood pressure instability, specifically, orthostatic hypotension (a drop in blood pressure when moving from lying flat on your back to an upright position). The main questions it aims to answer are: What are the various spinal sites and stimulation parameters that normalize and stabilize blood pressure during an orthostatic provoc... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/08/2023
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Spinal Cord Injuries, Hypotension, Orthostatic Hypotension, Spinal Cord Diseases, Cardiovascular Diseases, Trauma, Nervous System, Central Nervous System Diseases, Nervous System Diseases, Blood Pressure
Register for Updates
PyloPlus Urea Breath Test System Post Therapy Efficacy Confirmation Study
NCT05681689
Recruiting
This is a multi-center, non-randomized, open label study. Subjects will be enrolled if they are deemed eligible given the inclusion criteria. Subjects who meet all inclusion criteria and none of the exclusion criteria will be entered into the study. Subjects will be exposed to non-radioactive 13C-Urea with citric acid, and may submit a stool sample or undergo endoscopy for Rapid Urease Test and Histology samples. Center(s) will house a PyloPlus UBT Analyzer to document results. PyloPlus Analyze... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2023
Locations: Hudson County Clinical Trials Research Center, Union City, New Jersey
Conditions: Helicobacter Pylori Infection, Post-Treatment, Efficacy
Register for Updates
Combining Wearable Robotic Orthosis With Visual and Haptic Feedback to Enhance the Recovery of Upper Extremity Motor Function and ADL in Persons With Acute SCI
NCT05386537
Recruiting
This randomized clinical trial (RCT) is evaluating the usefulness of combining MyoMo robotic orthosis with visual and haptic feedback in ameliorating wrist/hand/UE movement capability, and increasing ADL and quality of life in people with acute SCI.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/03/2023
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: SCI - Spinal Cord Injury
Register for Updates