New Jersey is currently home to 1696 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Brunswick, Hackensack, Newark and Morristown. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Evaluate Impact of Exercise Program on Fatigue in Breast Cancer During Chemotherapy
NCT05704842
Recruiting
Assess feasibility of home exercise in reducing fatigue in subjects with breast cancer receiving curative intent chemotherapy. Subjects are randomized to control (no exercise) or intervention group (exercise). The PRO-CTCAE tool and FACIT Fatigue Scale are used to collect patient reported outcomes. Subjects submit data via mobile phone, tablet or computer. Assessments are weekly during chemotherapy (10-20 wks), at end of chemotherapy and 1, 3 and 6 months after chemotherapy.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/04/2024
Locations: Virtua Health, Voorhees, New Jersey
Conditions: Breast Cancer
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HomeStyles-2: Shaping HOME Environments and LifeSTYLES to Prevent Childhood Obesity
NCT04802291
Recruiting
Parents are children's primary role models, are food and physical activity gatekeepers, and create the structure/lifestyle environment within the home. Thus, parents strongly influence children's weight-related behaviors and have the opportunity to cultivate a "culture of health" within the home. Yet, there continues to be a dearth of evidence-based obesity prevention intervention programs, especially for families with children aged 6 to 11 years, commonly called the middle childhood years. The... Read More
Gender:
ALL
Ages:
Between 24 years and 50 years
Trial Updated:
04/04/2024
Locations: Rutgers University, New Brunswick, New Jersey
Conditions: Healthy Lifestyle, Home Environment Related Disease, Cognitive Change, Child Behavior, Child Obesity, Parenting, Parents, Parent-Child Relations
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Acute Effects of Walking Exercise on Brain Functioning in Multiple Sclerosis
NCT06233370
Recruiting
The project will involve a within-subjects, repeated-measures research design. Participants will initially be screened for relevant inclusion/exclusion criteria for maximizing safety of participating in an exercise study. If a participant meets those inclusion/exclusion criteria, they will visit Kessler Foundation three times. The first visit will involve a baseline session where participants will complete several cognitive tests. This will be followed by a training session, where participants w... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
04/03/2024
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Multiple Sclerosis
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RADIANT: Pre-op Radiation With Abemaciclib and Letrozole
NCT06139107
Recruiting
This phase 1b study investigates the safety and feasibility of combining pre-operative radiation therapy with Cyclin-Dependent Kinase 4 (CDK4/6) inhibitors in participants with hormone receptor positive/HER2 negative (HR+/HER2-) breast cancer. The study aims to assess the benefits of concurrent use of these treatments in a specific participant population, focusing on their safety and tolerability. The hypothesis is that the combination therapy will be well-tolerated, providing valuable insights... Read More
Gender:
FEMALE
Ages:
60 years and above
Trial Updated:
04/01/2024
Locations: Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
Conditions: Breast Cancer
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Statins for Reduction of Cardiac Toxicity in Patients Receiving HER2 Targeted
NCT05559164
Recruiting
This study proposes that the addition of statins reduces the treatment delays or early discontinuations secondary to cardiotoxicity in patients with Stage I-III HER2 positive breast being treated with anti-HER2 therapy.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/01/2024
Locations: Trinitas Hospital and Comprehensive Cancer Center, Elizabeth, New Jersey
Conditions: Cardiac Toxicity, Early-stage Breast Cancer
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Investigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS
NCT04855825
Recruiting
The purpose of this research study is to evaluate the usefulness of a wearable robotic exoskeleton device (Ekso-GT), to improve learning and memory, and gait therapy in persons with walking disability due to Multiple Sclerosis. The study will evaluate the mobility, learning and memory, and walking abilities of individuals with multiple sclerosis who went through the traditional as compared to others who used the robotic exoskeleton as part of their therapy.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
04/01/2024
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Multiple Sclerosis, Gait Disorders, Neurologic, Motility Disorder, Cognitive Impairment
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Use of Prophylactic Antibiotics Prior to OnabotulinumtoxinA
NCT05519072
Recruiting
This study aims to show that lack of antibiotic prophylaxis to those undergoing bladder Botox injections is not significantly inferior to administering prophylaxis. By proving this, the investigators aim to decrease antibiotic use in this setting to combat the growing issue of antibiotic resistance. Participants will be randomized to antibiotic or no treatment arm. Those randomized to the treatment arm will receive oral antibiotics for 2 days pre-treatment, on the treatment day, and 2 days post... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
03/25/2024
Locations: Atlantic Health, Morristown, New Jersey
Conditions: Antibiotic Prophylaxis
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Behavioral Exposure for Introceptive Tolerance RCT
NCT05398276
Recruiting
Behavioral Exposure for Interoceptive Tolerance (BE-FIT) is a mechanism-informed behavioral intervention to target exercise anxiety. The three primary components of BE-FIT include: (1) exposure to feared bodily sensations and exercise; (2) prevention of safety behavior use before/during/after exercise, and (3) use of a wrist-worn activity monitor for physical activity (PA) feedback and activity goal setting. Evidence from the investigators' Stage I trial indicated that BE-FIT is feasible, accept... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
03/25/2024
Locations: RWJ Cardiac Rehab at East Brunswick, East Brunswick, New Jersey
Conditions: Exercise Sensitivity, Introceptive Exposure, Anxiety, Cardiac Rehabilitation
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Treatment With Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI
NCT05180032
Recruiting
The objective of the proposed work is to determine whether administration for 12 months of romosozumab (evenity) followed by 12 months of denosumab (prolia) will maintain bone mass at the knee in subjects with chronic SCI.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/21/2024
Locations: Kessler Institute for Rehabilitation, West Orange, New Jersey
Conditions: Osteoporosis, Spinal Cord Injuries
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Modulating Reward Learning Using Transcranial Magnetic Stimulation
NCT06323057
Recruiting
Our specific aim is to examine the effects of TMS on reward processing during goal-directed behavior. In these experiments the investigators will utilize a scalp-recorded brain oscillation called frontal midline theta that is believed to index the sensitivity of the cingulate cortex to reward feedback. Here the investigators will asked whether this electrophysiological signal can be modulated up or down using TMS while participants engage in decision making tasks, and if so, whether it would aff... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
03/20/2024
Locations: Rutgers University - Newark, Newark, New Jersey
Conditions: Behavior
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Sequential TAS-OX Alternating With TAS-IRI Plus Bevacizumab for Late-Line Metastatic Colorectal Cancer
NCT05806931
Recruiting
This study is to evaluate the disease control rate and time to progression of the sequential combination of oxaliplatin with an alternative anti-metabolite Trifluridine/tipiracil hydrochloride mixture, TAS-102,(TAS-OX) as well as irinotecan in combination with TAS-102 oxaliplatin(TAS-OX) + Bevacizumab in late-line metastatic colorectal cancer (mCRC)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: Trinitas Hospital and Comprehensive Cancer Center, Elizabeth, New Jersey
Conditions: Colon Cancer, Rectal Cancer
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Microbiotic Product to Promote Microbiome Health and Improve Chemotherapy Delivery
NCT05296681
Recruiting
This phase II trial tests whether NBT-NM108 works in reducing chemotherapy-induced diarrhea in patients with colon cancer that has spread to other places in the body (metastatic). Irinotecan is one of the most used medicine for colon cancer, but it leads to diarrhea in most patients receiving it and among some of them, severe diarrhea can occur. NBT-NM108 is a high dietary fiber formula that is developed based on research findings that have shown that high fiber diets can help maintain healthy b... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: Robert Wood Johnson University Hospital, Hamilton, Hamilton, New Jersey
Conditions: Metastatic Colon Carcinoma, Stage IV Colon Cancer AJCC v8, Stage IVA Colon Cancer AJCC v8, Stage IVB Colon Cancer AJCC v8, Stage IVC Colon Cancer AJCC v8
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