New Jersey is currently home to 1675 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Brunswick, Hackensack, Newark and Morristown. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Coflex PS3 Actual Conditions for Use Study
Recruiting
A 2 and 5 year evaluation of clinical outcomes in the treatment of degenerative spinal stenosis with concomitant low back pain by decompression with additional stabilization using the coflex® Interlaminar Technology for FDA Actual Conditions of Use Study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/04/2024
Locations: St. Joseph's Medical Center, Wayne, New Jersey
Conditions: Spinal Stenosis Lumbar
TeleRehab to Restore Upper Limb Function in People With Chronic TBI
Recruiting
The study aims to inform the subsequent large-scale clinical trial focused on using telerehabilitation techniques and technologies to improve upper limb function and quality of life.
Gender:
ALL
Ages:
Between 45 years and 75 years
Trial Updated:
01/03/2024
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Traumatic Brain Injury, Upper Extremity Dysfunction, Disability Physical
Cerebral Palsy Upper Extremity Orthotic Device
Recruiting
Upper extremity therapies for children with cerebral palsy (CP) have been validated for improving function in higher functioning patients. Those who function at the lowest end of the scale, on the Manual Ability Classification System scale (MACS) III-V, comprise 34-54% of the population, but as yet have no evidence-based interventions specific to their needs. Lower functioning children often retain some voluntary control of the elbow in spite of limited finger motion. A dynamic splint, or exoske... Read More
Gender:
ALL
Ages:
Between 4 years and 17 years
Trial Updated:
12/21/2023
Locations: Rutgers NJMS, Newark, New Jersey
Conditions: Cerebral Palsy
Improving Anticipatory and Compensatory Postural Responses to Avoid Falls After TBI
Recruiting
The purpose of this study is to assess a balance training program to see if it can be helpful to avoid falls in people who have had traumatic brain injuries (TBIs). The study will include 3 groups: TBI Intervention group , TBI Control Group, and healthy control group. TBI Intervention group - These individuals will participate in 16 anticipatory postural adjustments (APA) and compensatory postural adjustments (CPA) training sessions using the Neurocom Balance Platform. Each session will last f... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
12/18/2023
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Traumatic Brain Injury
Study to Improve Ambulation in Individuals With TBI Using Virtual Reality -Based Treadmill Training
Recruiting
The purpose of this research study is to test the effectiveness of virtual reality (VR) based treadmill training on walking ability. The study will also help to understand the changes in cognitive ability and brain activity as a result of VR-based treadmill training after a brain injury. The study will include 3 groups: C-MILL training group (CTG), Treadmill training group (TTG), and healthy control group (HCG). Individuals with brain injury will be randomly assigned to C-MILL training group,... Read More
Gender:
ALL
Ages:
Between 13 years and 35 years
Trial Updated:
12/18/2023
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Traumatic Brain Injury
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement
Recruiting
Patients undergoing transcatheter aortic valve replacement (TAVR) often have concomitant coronary artery disease (CAD) which may adversely affect prognosis. There is uncertainty about the benefits and the optimal timing of revascularization for such patients. There is currently clinical equipoise regarding the management of concomitant CAD in patients undergoing TAVR. Some centers perform routine revascularization with percutaneous coronary intervention (PCI) (either before or after TAVR), while... Read More
Gender:
ALL
Ages:
All
Trial Updated:
12/13/2023
Locations: Our Lady of Lourdes, Camden, New Jersey
Conditions: Aortic Stenosis, Coronary Artery Disease, Coronary Stenosis
Adaptive Radiation Planning for the Reduction of Radiation-Induced Toxicity in Patients With Stage II-IV Non-small Cell Lung Cancer
Recruiting
This phase II trial studies the effect of adaptive radiation planning in reducing side effects associated with radiation treatment and immunotherapy in patients with stage II-IV non-small cell lung cancer. Prior to radiation, patients undergo simulation, where they are positioned on the treatment table in a manner that can be reproduced each time they receive treatment in order to reach the tumor exactly at the same spot each time. However, a patient's tumor may shrink as they receive radiation,... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/12/2023
Locations: Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
Conditions: Locally Advanced Lung Non-Small Cell Carcinoma, Metastatic Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8, Unresectable Lung Non-Small Cell Carcinoma
History of Neonatology
Recruiting
This study traces the history of neonatology in the United States from the 1960s to the present with particular attention to the ways in which neonatologists developed criteria to make treatment decisions. I will be using oral history interviews as one source for a book that will document developments in the history of neonatology. I will identify potential research subjects through their publications in the field of neonatology and through word of mouth. I will locate them via the contact infor... Read More
Gender:
ALL
Ages:
All
Trial Updated:
12/11/2023
Locations: Rutgers University, New Brunswick, New Jersey
Conditions: Oral History
Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C Melanoma Patients
Recruiting
The trial aims to evaluate the efficacy of Daromun neoadjuvant treatment followed by surgery and adjuvant therapy to improve in a statistically significant manner the recurrence-free survival (RFS) of Stage IIIB/C melanoma patients with respect to the standard of care (surgery and adjuvant therapy).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/29/2023
Locations: Rutgers Cancer Institute, 195 Little Albany Street, New Brunswick, New Jersey
Conditions: Melanoma Stage IIIB/C
Pediatric Vasculitis Initiative
Recruiting
Childhood chronic vasculitis describes a group of rare life-threatening diseases that have in common inflammation of blood vessels in vital organs such as kidneys, lungs and brain. Most knowledge about them comes from adult patients. Severe disease requires aggressive life-saving treatments with steroids and some cancer drugs which can themselves cause damage, and increase risks of cancer and severe infections. Conversely, milder disease can be treated with less toxic drugs. Different classifica... Read More
Gender:
ALL
Ages:
20 years and below
Trial Updated:
11/27/2023
Locations: The Joseph M. Sanzari Children's Hospital, Hackensack, New Jersey
Conditions: Wegeners Granulomatosis (Granulomatosis With Polyangiitis), Microscopic Polyangiitis, Polyarteritis Nodosa, Takayasu Arteritis, Primary CNS Vasculitis, Unclassified Vasculitis, Eosinophilic Granulomatosis With Polyangiitis
Combinatory Rehabilitation Used for Substantially Helping Individuals With Traumatic Brain Injury
Recruiting
New learning and memory impairment (NLMI) is a common and devastating manifestation of TBI associated with substantial life burdens. Persons with moderate to severe TBI have shown improvement in NLM for prose material (e.g. story) as well as beneficial changes in default-mode network (DMN) activation during list-learning19 following treatment with the Kessler Foundation modified Story Memory Technique® (KF-mSMT®). Benefits, however, were moderate and did not yield downstream improvements in dail... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/16/2023
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Traumatic Brain Injury
Transdiagnostic Individual Behavioral Activation and Exposure Therapy
Recruiting
The Overall Aim of the this project is to compare treatment outcomes and change in putative treatment mediators in Individual Behavioral Activation Therapy (IBAT) against two active psychological interventions (Coping Cat, PASCET) and a wait-list control. Participants will be 200 youth (ages 9-17) diagnosed with a principal anxiety or depression disorder and their caregivers.
Gender:
ALL
Ages:
Between 9 years and 17 years
Trial Updated:
11/15/2023
Locations: Youth Anxiety and Depression Clinic, Piscataway, New Jersey
Conditions: Anxiety Disorders, Depression