New Jersey is currently home to 1651 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Brunswick, Hackensack, Newark and Morristown. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Corneal Collagen Crosslinking for Keratoconus and Ectasia Using Riboflavin/Dextran or Riboflavin/Methylcellulose
NCT04897503
Recruiting
This study is being conducted to evaluate the safety and efficacy of isotonic riboflavin for corneal collagen crosslinking for keratoconus and corneal ectasia. will determine the safety and efficacy of corneal collagen crosslinking (CXL) performed with two different riboflavin formulations for reducing corneal curvature.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
12/30/2022
Locations: Cornea and Laser Eye Institue - Hersh Vision Group, Teaneck, New Jersey
Conditions: Keratoconus, Corneal Ectasia
Register for Updates
Exercise Dose and Metformin for Vascular Health in Adults With Metabolic Syndrome
NCT04817787
Recruiting
Arterial disease is the leading cause of morbidity/mortality in Metabolic syndrome (MetS). This occurs early as evidenced by arterial dysfunction that, in turn, raises blood pressure and glucose. Health organizations recommend exercise in an intensity based manner to promote cardiovascular adaptation and prevent disease. Metformin is a common anti-diabetes medication that reduces future type 2 diabetes and cardiovascular risk. However, the optimal exercise dose to be combined with metformin for... Read More
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
12/23/2022
Locations: Loree Gymnasium, New Brunswick, New Jersey
Conditions: Metabolic Syndrome, Insulin Sensitivity, Vascular Stiffness
Register for Updates
Comparison of Two Group Wellness Interventions for Individuals With Neurologic Conditions and Their Support Persons
NCT05048966
Recruiting
Approximately 5.3 million people live with a long-term disability resulting from a traumatic brain injury (TBI) and between 5-8% of those older than 60 suffer from Alzheimer's disease or other forms of dementia (ADRD). Consequences of these conditions can result in dramatic and persistent changes in functioning, impacting not only the patients, but also loved ones who become informal support persons. Many existing services help the family in the moment, but do not address long-term wellness. Thu... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/14/2022
Locations: Kessler Foundation, East Hanover, New Jersey
Conditions: Traumatic Brain Injury, Mild Traumatic Brain Injury, Alzheimer's Disease, Brain Injury Traumatic Moderate, Brain Injury Traumatic Severe, Dementia
Register for Updates
2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C
NCT04012996
Recruiting
A multi-center, prospective, randomized, controlled comparison of the prodisc C SK and prodisc C Vivo to the control, a similar, legally marketed total disc replacement device in subjects with symptomatic cervical disc disease (SCDD).
Gender:
ALL
Ages:
Between 18 years and 69 years
Trial Updated:
10/27/2022
Locations: University Spine Center, Wayne, New Jersey
Conditions: Symptomatic Cervical Disc Disease
Register for Updates
REFINE Study: A Study In a Novel Interspinous Fusion Device In Subjects With Low Back Pain
NCT05504499
Recruiting
The purpose of this study is to evaluate the effectiveness and safety of the use of Aurora Spine ZIP™ MIS Interspinous Fusion System and bone graft material in fusion in patients with chronic low back pain that present with degenerative disc disease with concurrent neurogenic claudication.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/16/2022
Locations: The Pain Management Center, Voorhees, New Jersey
Conditions: Lumbar Spinal Stenosis
Register for Updates
Evaluation of the FELLAS Responsible Fatherhood Project
NCT05412641
Recruiting
The Partnership for Maternal and Child Health of Northern New Jersey, Inc. (PMCH) is implementing a fatherhood project with the goal of strengthening father-child engagement, improving economic stability, and improving healthy marriage/relationship skills among participants. FELLAS serves community-based fathers 18 years of age or older who reside in Essex County, New Jersey and have at least one child under the age of 24. The program model has three components: to improve responsible parenting... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
06/07/2022
Locations: Partnership for Maternal & Child Health of Northern New Jersey, Newark, New Jersey
Conditions: Responsible Fatherhood
Register for Updates
KRT-232 in Combination With TL-895 for the Treatment of R/R MF and KRT-232 for the Treatment of JAKi Intolerant MF
NCT04640532
Recruiting
This study evaluates KRT-232 in Combination With TL-895 for the Treatment of Relapsed or Refractory Myelofibrosis and KRT-232 for the Treatment of JAK Inhibitor Intolerant Myelofibrosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/05/2022
Locations: Columbia University Medical Center, Fort Lee, New Jersey
Conditions: Myelofibrosis, Post-PV MF, Post-ET Myelofibrosis, Primary Myelofibrosis
Register for Updates
A Study Investigating Lu AG22515 in Healthy Adults
NCT05303246
Recruiting
The main goal of this study is to learn more about the safety of a drug called Lu AG22515. During the trial, healthy adult participants will receive a single dose of Lu AG22515 or a placebo (normal saline solution).
Gender:
All
Ages:
Between 19 years and 60 years
Trial Updated:
03/21/2022
Locations: Frontage Clinical Services, Inc., Secaucus, New Jersey
Conditions: Healthy Participants
Register for Updates
Study of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199), With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL
NCT05211856
Recruiting
The purpose of this study is to evaluate the efficacy and safety of acalabrutinib in combination with venetoclax and acalabrutinib in combination with venetoclax with and without obinutuzumab compared to chemoimmunotherapy in subjects with previously untreated CLL.
Gender:
All
Ages:
Between 18 years and 130 years
Trial Updated:
01/14/2022
Locations: Research Site, Brick, New Jersey
Conditions: Chronic Lymphocytic Leukemia
Register for Updates
Early Feasibility Study of the Cardiac Implants Percutaneous Ring Annuloplasty System
NCT04890821
Recruiting
An early feasibility study to evaluate the safety and performance of 1) the transcatheter delivery and implantation of the Cardiac Implants (CI) annuloplasty ring and 2) the adjustment of the ring approximately 90 days following implantation in patients suffering from ≥ moderate functional tricuspid regurgitation (FTR).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/18/2021
Locations: Hackensack University Medical Center, Hackensack, New Jersey
Conditions: Tricuspid Regurgitation Functional
Register for Updates
Bupivacaine/Epinephrine +Dexamethasone vs. Liposomal Bupivacaine
NCT03906617
Recruiting
This study will assess analgesia after robotic lung surgery. Subjects will be randomized to receive wound infiltration and intercostal nerve block with either liposomal bupivacaine or bupivacaine/epinephrine + dexamethasone. Liposomal bupivacaine is a newer local anesthetic product and has not been compared to a combination of bupivacaine/epinephrine + dexamethasone in the context of pain control after robotic lung surgery.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
11/11/2021
Locations: Cooper University Hospital, Camden, New Jersey
Conditions: Robotic Lung Surgery
Register for Updates
To Assess the Safety, Tolerability and Efficacy of Itacitinib Immediate Release Tablets in Participants With Primary or Secondary Myelofibrosis Who Have Received Prior Ruxolitinib and/or Fedratinib Monotherapy. (LIMBER-213)
NCT04821791
Recruiting
This is a 2-part study. In Part 1, participants will be dosed at 2 different dose levels in order to select the RP2D for Part 2 of the study.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/27/2021
Locations: New Jersey Hematology Oncology Associates Llc, Brick, New Jersey
Conditions: Myelofibrosis, Polycythemia Vera, Thrombocythemia
Register for Updates