Pennsylvania is currently home to 3393 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Philadelphia, Pittsburgh, Hershey and Allentown. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
PRIME Care (PRecision Medicine In MEntal Health Care) 2.0
NCT04958824
Recruiting
Background: In the last several years, commercial pharmacogenetic (PGx) testing for the selection of psychotropic medications has become widespread as a means of implementing "precision medicine", with some insurers electing to cover the cost of testing. Mostly these efforts have focused on the decision of choosing a medication. Polypharmacy has become widespread and often the norm in patients with more severe of chronic illness. Objectives: This project is designed to evaluate the utility of P... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
07/06/2021
Locations: Cpl Michael J Crescenz VAMC, Philadelphia, Pennsylvania
Conditions: Psychiatric or Mood Diseases or Conditions
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An Extension Study to Evaluate the Efficacy and Safety of HORIZANT in Adolescents With Moderate-to-Severe Primary RLS
NCT02633683
Recruiting
The objectives of the trial are to evaluate the long-term efficacy and safety of HORIZANT (Gabapentin Enacarbil) 600 mg daily, for the treatment of RLS in adolescents (13 to 17 years of age) diagnosed with moderate-to-severe primary RLS.
Gender:
All
Ages:
Between 13 years and 17 years
Trial Updated:
06/07/2021
Locations: The Sleep Center at the Childrens Hospital of Philadelphia, Philadelphia, Pennsylvania
Conditions: RLS
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Immunity After COVID-19 Vaccination
NCT04883164
Recruiting
The purpose of the research is to evaluate new blood tests, which measure immunity to the COVID-19 coronavirus after vaccination. These tests will be used to measure T-cell and antibody immunity after COVID-19 vaccination. Recent studies show that less than one-fifth of chronically immunosuppressed transplant recipients developed anti-receptor-binding domain antibodies after the first dose of the Pfizer vaccine (Boyarski, 2021). ood sampling at periodic intervals. These samples will be used to... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
05/11/2021
Locations: Plexision, Pittsburgh, Pennsylvania
Conditions: Immunity to COVID-19
Register for Updates
Online Wellness Intervention for College Students
NCT04740411
Recruiting
We are evaluating the effects of an online single-session mental health intervention (the Common Elements Toolbox; COMET). To evaluate COMET, we are conducting a randomized controlled trial with college students attending American universities. Students will be randomized to the COMET condition or to a wait-list control condition.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/11/2021
Locations: University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Depression, Anxiety, Well-being
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Prospective Evaluation of Chronic Pancreatitis for Epidemiologic and Translational Studies, the PROCEED Study
NCT04753255
Recruiting
This study gathers information on patients at different stages of chronic pancreatitis to better understand the natural course and risk factors associated with pancreatitis. Chronic pancreatitis is a disease that occurs when the pancreas is inflamed (swollen and irritated) all of the time. It is important for doctors to diagnose chronic pancreatitis in the beginning stages of the disease. Over time, as chronic pancreatitis gets worse, the pancreas may stop working correctly. Since treatment opti... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/22/2021
Locations: University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania
Conditions: Acute Pancreatitis, Chronic Pancreatitis
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Attachment-Based Family Therapy for Adolescents With Binge Eating
NCT04779801
Recruiting
The purpose of this study is to examine whether Attachment-Based Family Therapy (ABFT), a well-validated treatment for adolescents with depression and suicidality, is feasible and acceptable for adolescents with binge eating and their families.
Gender:
All
Ages:
Between 12 years and 22 years
Trial Updated:
03/02/2021
Locations: Drexel University, Philadelphia, Pennsylvania
Conditions: Bulimia Nervosa, Binge-Eating Disorder, Other Specified Feeding or Eating Disorder
Register for Updates
Conversion of Seddon III Nerve Injury to Seddon I/II Nerve Injury
NCT03236064
Recruiting
This study will evaluate the safety and efficacy of PEG 3350 for use in nerve repair.
Gender:
All
Ages:
Between 16 years and 65 years
Trial Updated:
01/22/2021
Locations: WellSpanYork Hospital, York, Pennsylvania
Conditions: Injury of Other Nerves at Wrist and Hand Level of Unspecified Arm, Initial Encounter
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PrEP Awareness, Barriers and Facilitators for PrEP Uptake, and Dosing Mechanisms on Willingness to Take PrEP Among MSM
NCT04719364
Recruiting
The investigators are conducting a one and one-half year mixed-methods study to evaluate self-reported sexual risk, knowledge and barriers/facilitators of PrEP use, and preferences of oral, injectable, and implantable PrEP treatment modalities-as a function of race and age, and experience with intersectional discrimination. The first qualitative phase of our study would be conducted over the first eight months, followed by a quantitative phase that will collect data via online cross-sectional su... Read More
Gender:
Male
Ages:
18 years and above
Trial Updated:
01/20/2021
Locations: Drexel Dornsife School of Public Health, Philadelphia, Pennsylvania
Conditions: PrEP, Discrimination, Racial, Stigma, Social
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An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis
NCT04718818
Recruiting
The present study D5272C00001 (Legacy # 3151-201-008) seeks to evaluate the efficacy and safety of brazikumab versus placebo in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/19/2021
Locations: Research Site, Uniontown, Pennsylvania
Conditions: Ulcerative Colitis
Register for Updates
Prevention of Postoperative Nausea and Vomiting After Bariatric Surgery
NCT04644445
Recruiting
Postoperative nausea and vomiting are common occurrences following bariatric surgery, occurring in up to 80% of patients and contributing to increased healthcare utilization and delays in discharge. This study aims to evaluate the impact of a high-protein liquid diet on postoperative nausea, vomiting, and length of stay after laparoscopic or robotic sleeve gastrectomy.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/07/2020
Locations: Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
Conditions: Bariatric Surgery Candidate, Postoperative Nausea and Vomiting, Morbid Obesity
Register for Updates
Restoring Non-Emergent Cardiovascular Care in the Peri- COVID-19 Era
NCT04636021
Recruiting
Pre-procedure and Short-Term COVID-19 Testing of Outpatients Undergoing Non-emergent Invasive Cardiovascular Procedures
Gender:
All
Ages:
All
Trial Updated:
11/18/2020
Locations: UPMC Pinnacle Harrisburg, Harrisburg, Pennsylvania
Conditions: Corona Virus Infection
Register for Updates
Spinal Cord Injury Registry - North American Clinical Trials Network
NCT00178724
Recruiting
The NACTN Spinal Cord Injury Registry is a network of clinical centers collecting de-identified data from patients admitted through the Emergency Department of a NACTN center at the time of injury with an initial (first time) spinal cord injury (SCI). Information will be collected on the natural history of SCI and course of treatment through the first 12 months from the date of injury or long as medically indicated. Data collected includes imaging information from CT or MRI scans, neurological a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/22/2020
Locations: Thomas Jefferson University, Philadelphia, Pennsylvania
Conditions: Spinal Cord Injury
Register for Updates