Virginia is currently home to 1850 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Richmond, Charlottesville, Norfolk and Fairfax. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
RCT: Early Feeding After PEG Placement
NCT04110613
Recruiting
Randomized controlled trial to establish evidence on which to base timing of enteral feeding after bedside PEG placement in ventilated Trauma and Surgical ICU patients.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
10/18/2021
Locations: Carilion Roanoke Memorial Hospital, Roanoke, Virginia
Conditions: Critical Illness, Malnutrition, Gastrostomy, Procedural Sequelae, Trauma, Surgery, Mechanical Ventilation
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Myeloma-Developing Regimens Using Genomics (MyDRUG)
NCT03732703
Recruiting
The MyDRUG study is a type of Precision Medicine trial to treat patients with drugs targeted to affect specific genes that are mutated as part of the disease. Mutations in genes can lead to uncontrolled cell growth and cancer. Patients with a greater than 25% mutation to any of the following genes; CDKN2C, FGFR3, KRAS, NRAS, BRAF V600E, IDH2 or T(11;14) can be enrolled to one of the treatment arms. These arms have treatments specifically directed to the mutated genes. Patients that do not have a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/09/2021
Locations: Virginia Cancer Specialists, Fairfax, Virginia
Conditions: Relapsed Refractory Multiple Myeloma
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Prospective US Radiofrequency SUI Trial
NCT04720352
Recruiting
PURSUIT: Prospective US Radiofrequency SUI Trial (VI-17-06) is a prospective, randomized, sham controlled, double blind study in premenopausal women with stress urinary incontinence. The study will be conducted in 390 subjects, randomized 2:1 with active or sham treatment. Study duration is 12 months post treatment. The primary objective is to evaluate the efficacy of the Viveve treatment, SUI protocol, in improving mild to moderate stress urinary incontinence (SUI), assessed using the 1-hour Pa... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/19/2021
Locations: Health Research of Hampton Roads, Inc, Newport News, Virginia
Conditions: Urinary Incontinence, Stress
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Aspirin for the Prevention of Preeclampsia in Women With Stage 1 Hypertension
NCT04908982
Recruiting
In 2017, the American College of Cardiology and the American Heart Association changed the diagnostic criteria for hypertension in non-pregnant adults. The parameters for the diagnosis of stage 1 hypertension were revised from a systolic blood pressure (BP) of 140 to 130 mm Hg and a diastolic BP of 90 to 80 mm Hg. Based on new criteria, stage 1 hypertension is associated with a 2-3 fold increased risk of preeclampsia. There are no data regarding prevention of preeclampsia in women with stage 1 h... Read More
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
06/25/2021
Locations: Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Eastern Virginia Medical School, Norfolk, Virginia
Conditions: Pre-Eclampsia
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Multi-Center Study to Evaluate the Efficacy and Safety of Sildenafil Cream (3.6%) in Premenopausal Patients With Female Sexual Arousal Disorder
NCT04948151
Recruiting
This study is looking to minimize side effects, while maintaining and potentially improving the therapeutic benefit to patients suffering from Female Sexual Arousal Disorder by providing a topical preparation of Sildenafil locally to the vulvar-vaginal tissue.
Gender:
Female
Ages:
21 years and above
Trial Updated:
06/24/2021
Locations: Health Research of Hampton Roads, Inc., Newport News, Virginia
Conditions: Female Sexual Arousal Disorder
Register for Updates
Self-Reports of Executive Functions in Persons With Parkinson's Disease and Their Significant Others
NCT04928027
Recruiting
The investigators are conducting a study to compare the self-reports of executive functions (that is to say, what role cognitive processes such as working memory and attention) in persons with Parkinson's Disease to the reports of executive functions completed by their significant others. To conduct this study, the investigators need the participation of persons who are diagnosed with Parkinson's Disease and their significant others.
Gender:
All
Ages:
Between 30 years and 79 years
Trial Updated:
06/15/2021
Locations: Old Dominion University, Norfolk, Virginia
Conditions: Parkinsonism or Parkinson's Disease Nos
Register for Updates
Waveform and Spectral Characteristics of Perioperative Wheezing
NCT04873882
Recruiting
With the aid of computerized sound analysis, digital acoustic monitoring could provide a more sensitive, specific, and quantifiable indicator for perioperative respiratory abnormalities including wheezing. It is probable that the digital stethoscope has utility in the detection, monitoring, and resolution following treatment of acoustic changes characteristic of turbulent respiratory gas flow due to wheezing and/or the incomplete resolution of atelectasis following the re-initiation of ventilati... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/29/2021
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Respiratory Sounds, Thoracic Surgery
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Efficacy of Contrast Enhanced Voiding Urosonography for Urodynamic Studies
NCT04738539
Recruiting
The investigators will assess the feasibility of replacing fluoroscopy/iodinated contrast with ultrasound/sulfur hexafluoride lipid-type A microspheres during routine urodynamic studies.
Gender:
All
Ages:
18 years and below
Trial Updated:
04/27/2021
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Myelomeningocele, Neurogenic Bladder, Tethered Cord Syndrome, Bladder, Neurogenic, Urologic Diseases, Neurologic Dysfunction
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Breaking Bad News to Family Members in a Pandemic
NCT04638530
Recruiting
Resident education on breaking bad news and conducting end of life conversations has been shown to improve comfort levels with having these conversations. Interventions with OB/GYN residents specifically have used a combination of didactics, resident role-playing and ultimately interaction with standardized patients with feedback from palliative care specialists. These interventions can be costly and also are not practical during the pandemic training environment where resident has transitioned... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/26/2021
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Resident Education, Patient Communication, Breaking Bad News to Patients Remotely, Telemedicine
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ZILRETTA™ for Treatment of Idiopathic Adhesive Capsulitis
NCT04831255
Recruiting
Adhesive capsulitis is a fairly common orthopedic condition that causes pain and loss of range of motion. There are a variety of ways to treat adhesive capsulitis, one of them being an intra-articular steroid injection. This is done to help decrease the inflammatory response caused by adhesive capsulitis. In this study, all participants will receive an intra-articular glenohumeral injection of ZILRETTA and will be followed up with at four time points over 1 year to observe pain, function and ran... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/05/2021
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Adhesive Capsulitis, Frozen Shoulder, Adhesive Capsulitis of Shoulder
Register for Updates
Microfluidic-based Tactile Sensor in Cardiac Rehabilitation
NCT04812600
Recruiting
This study will examine the impact of cardiac rehabilitation on blood vessel health using a newly developed microfluidic-based tactile sensor to assess blood vessel health. The participants will have their blood vessel health measured using a sensor that is placed on top of the skin over the artery before and after exercise (1, 3, 5, 10, 30 and 60 mins). The investigators will study these responses at the first session of cardiac rehabilitation and following 1 and 4 weeks of cardiac rehabilitati... Read More
Gender:
All
Ages:
Between 45 years and 70 years
Trial Updated:
03/19/2021
Locations: Sentara Heart Hospital, Norfolk, Virginia
Conditions: Cardiovascular Diseases, Vascular Stiffness, Endothelial Dysfunction
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Evaluation of Exparel Adductor Canal Field Block for Pain Control After ACL Reconstruction
NCT04764916
Recruiting
This is a prospective, randomized study for adult patients presenting to the Carilion Clinic Institute of Orthopedics and Neurosurgery. Patients undergoing isolated ACL reconstruction will be eligible for inclusion. All patients will receive an adductor canal block (either with bupivacaine or Exparel. Patients will be given a pain diary for self-report of pill counts, pain scores, block duration, and pain control satisfaction). Pill counts and pain scores will also be taken by a team member at t... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/18/2021
Locations: Carilion Clinic Institute for Orthopaedics and Neurosciences, Roanoke, Virginia
Conditions: Anterior Cruciate Ligament Tear, Pain, Postoperative, Opioid Use
Register for Updates