There are currently 298 active clinical trials seeking participants for Cancer research studies. The states with the highest number of trials for Cancer participants are California, Texas, New York and Florida.
Evaluating a Pharmacogenetic Testing Panel in Patients Suspected to be at Increased Risk for Pharmacogenetics-related AEs While Receiving Fluoropyrimidine or Irinotecan Therapy
NCT05583422
Recruiting
This study will be evaluating patients suspected to carry DPYD or UGT1A1 variants based off of Michigan Genomics Initiative (MGI) results. Standard of care treatment will be initiated with either Fluoropyrimidine or Irinotecan therapy. Retrospective collection of treatment related AEs and SAEs, dose delays, dose reductions, and treatment discontinuations will be completed.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/22/2024
Locations: University of Michigan Rogel Cancer Center, Ann Arbor, Michigan
Conditions: Cancer
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Screening for and Responding to Food Insecurity Among Infusion Patients
NCT05889780
Recruiting
Food insecurity impacts 1 in 8 people in the United States and 1 in 4 people receiving cancer treatment. Food insecurity is associated with poor dietary quality, adverse health conditions (e.g., Type 2 diabetes, overweight and obesity, hypertension), and worse cancer treatment outcomes. To effectively address food insecurity among people with cancer, screening and effective response programs are needed. The Food to Overcome Disparities (FOOD) program screens breast cancer patients for food inse... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/22/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Cancer, Diet, Healthy, Nutrition, Healthy
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Oral Administration of STC-15 in Subjects With Advanced Malignancies
NCT05584111
Recruiting
This Phase 1, multi-center, open-label, first-in-human study evaluates multiple ascending daily oral doses of STC-15 in Q3W treatment cycles in a 3+3 cohort design with dose levels determined by a modified Fibonacci algorithm. The study is designed to systematically assess safety and tolerability, pharmacokinetics, pharmacodynamics and clinical activity of STC-15 in adult subjects with advanced malignancies. Dose levels for further evaluation in expansion cohorts will be selected based on all av... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/21/2024
Locations: Honor Health, Scottsdale, Arizona +2 locations
Conditions: Advanced Cancer, Advanced Solid Tumor, Cancer
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The Gut Microbiome and Immunotherapy Response in Solid Cancers
NCT06050733
Recruiting
The aim of this study is characterize the gastrointestinal microbiomes of patient with solid cancer undergoing standard of care treatment with programmed cell death protein 1 (PD-1) /programmed cell death ligand (PD-L1) blockade.
Gender:
All
Ages:
Between 35 years and 75 years
Trial Updated:
01/18/2024
Locations: University of Texas Medical Branch, Galveston, Texas
Conditions: Cancer
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A Dose Finding Phase 1 of Sarilumab Plus Capecitabine in HER2/Neu-Negative Metastatic Breast Cancer and a Single-arm, Historically-controlled Phase 2 Study of Sarilumab Plus Capecitabine in Stage I-III Triple Negative Breast Cancer With High-Risk Residual Disease (EMPOWER)
NCT04333706
Recruiting
This study looks to advance a novel and potent strategy to eliminate minimal residual disease (MRD) in triple negative breast cancer (TNBC) present even after multimodal treatment, thereby improving survival and increasing cure rate in this aggressive cancer. Patients with locally advanced TNBC are at high risk of developing lethal metastatic disease within 2 years of diagnosis, especially for those without a pathologic complete response (pCR) after neoadjuvant chemotherapy. The high risk occurs... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
01/16/2024
Locations: Los Angeles General Medical Center, Los Angeles, California +2 locations
Conditions: Breast, Metastatic, Triple Negative, Cancer, Disseminated Tumor Cell
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Bladder and Bone Effects of Pelvic Radiation Therapy in Childhood Cancer Survivors
NCT05818462
Recruiting
The aim of this study is to measure and evaluate the effects of pelvic external beam radiation therapy (EBRT) on lower urinary tract (LUT) function and bone mineralization.
Gender:
All
Ages:
Between 2 years and 40 years
Trial Updated:
01/12/2024
Locations: Colorado Research Center, Aurora, Colorado
Conditions: Cancer, Childhood Cancer
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Checking Out Checking In: The Development and Validation of an Electronic Screening Tool for Pediatric Psychosocial Distress
NCT02423031
Recruiting
Background: - Medical problems and treatments can cause stress in some people. Researchers want to learn more about how to measure distress in young people with medical illnesses. A screening tool called Checking In will be developed in order to help researchers find ways to identify concerns and stresses common to this group. Objective: - To create a screening tool that will help health care providers identify psychological and social distress in young people with serious illnesses. Eligibi... Read More
Gender:
All
Ages:
Between 8 years and 21 years
Trial Updated:
01/12/2024
Locations: Children's Hospital Colorado, Aurora, Colorado +3 locations
Conditions: Cancer
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Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Metastatic Cancer Patients
NCT04353973
Recruiting
This study aims to determine if web-based eHealth delivery of pre-test and/or post-test counseling in cancer patients and/or those at risk for cancer can provide equal or improved cognitive and affective outcomes when compared to the standard of care delivery model.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/12/2024
Locations: Abramson Cancer Center at University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Cancer
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Influence of Adiposity on IGF-1 and Fitness Response to Exercise in Cancer Survivors
NCT05558384
Recruiting
This is a pilot feasibility study of an investigation of the influence of excess adiposity on cardiorespiratory fitness (CRF), insulin-like growth factor-1 (IGF-1), and metabolic responses to a standardized aerobic exercise program in cancer survivors. This investigation attempts to isolate the influence of adiposity on these responses. We will enroll overweight, obese, and normal weight cancer survivors with a primary diagnosis of breast, prostate, or colorectal cancer who have completed all ca... Read More
Gender:
All
Ages:
Between 21 years and 79 years
Trial Updated:
01/12/2024
Locations: University of Colorado Hospital, Aurora, Colorado
Conditions: Cancer, Overweight and Obesity
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Trial of DFP-14927 in Advanced Solid Tumors
NCT03943004
Recruiting
This is a Phase I, open-label, single-arm, dose escalation study of DFP-14927 intravenous infusion administered to patients with refractory or relapsed solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/11/2024
Locations: UCLA Department of Medicine- Hematology/Oncology, Los Angeles, California +1 locations
Conditions: Solid Tumor, Cancer
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Perceptions of Hospital Care at Home for Patients With Cancer: A Qualitative Study of Cancer Providers, Patients and Caregivers.
NCT05694650
Recruiting
The objective of this qualitative research study is to assess the knowledge, attitudes and beliefs of cancer care providers, patients with cancer and caregivers regarding hospital care at home. We aim to conduct qualitative interviews to inform implementation of future on oncology hospital care at home programs
Gender:
All
Ages:
18 years and above
Trial Updated:
01/11/2024
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Cancer
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Behavioral Economic Strategies to Improve PRO Adherence
NCT06013176
Recruiting
The main purpose of this research study is to evaluate the implementation and effectiveness of patient- and nurse-directed strategies across in-clinic and remote patient reported outcome (PRO) monitoring settings, using a three-arm pragmatic cluster randomized controlled trial. Additionally, the goal is to evaluate moderators of implementation effects on PRO monitoring. Eligible patients will be randomized independently to: (1) usual practice (i.e., encounter-based PRO administration via patien... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/11/2024
Locations: Abramson Cancer Center, Philadelphia, Pennsylvania
Conditions: Cancer
Register for Updates