There are currently 301 active clinical trials seeking participants for Cancer research studies. The states with the highest number of trials for Cancer participants are California, Texas, New York and Florida.
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of up to Two Doses of Psilocybin for the Treatment of Major Depressive Disorder in Adults With Cancer
NCT05947383
Recruiting
This is a Phase 2, single-center study to explore the efficacy, safety, and tolerability of up to two 25-mg doses of psilocybin administered at an interval of 9 to 10 weeks in patients with MDD and cancer. This two-part study will administer a fixed dose (25 mg) of psilocybin in a double-blind, randomized, placebo-controlled portion (Dosing Session 1) and subsequently allow rollover into an open-label portion (Dosing Session 2; fixed dose of psilocybin, 25 mg) for patients who do not achieve rem... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/07/2023
Locations: Sunstone Medical, PC, Rockville, Maryland
Conditions: Cancer, Major Depressive Disorder
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Ezra Faster Scan Study
NCT05385718
Recruiting
The Ezra Faster Scan study uses non-invasive magnetic resonance imaging (MRI) technology that can "visually" detect early and late-stage cancer, and other pathologies. MRIs use a magnetic field and radio waves to create a 3-dimensional (3D) image of an individual's body without using ionizing radiation. The purpose of this research is to decrease the amount of time required by an individual to complete an early cancer screening comprehensive magnetic resonance imaging (MRI) scan, such as the Ez... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/06/2023
Locations: Various Locations, Beverly Hills, California +4 locations
Conditions: Medical Oncology, Cancer, Healthy
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Intervention to Educate and Improve Underrepresented Populations' Participation in Clinical Trials
NCT04863092
Recruiting
This proposal aims to leverage ongoing community outreach efforts and the Cancer Center's aims to improve recruitment to clinical trials by educating the catchment and making referrals to engage current UCCC patients not taking advantage of available CTs at this institution and affiliated hospitals. The Cancer Prevention and Control Program within UCCC works to develop and evaluate novel approaches to primary prevention, disseminate preventative interventions in population-based settings, and to... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/30/2023
Locations: University of Colorado Hospital, Aurora, Colorado
Conditions: Cancer
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Phase 1 Trial of LVGN7409 (CD40 Agonist Antibody) as Single Agent and Combination Therapies in Advanced or Metastatic Malignancy
NCT04635995
Recruiting
LVGN7409 is a humanized monoclonal antibody that specifically binds to CD40, and acts as an agonist against CD40. This first in human study of LVGN7409 is designed to establish the maximum tolerated dose (MTD) and/or the recommended dose for expansion (RDE) as well as the recommended Phase 2 dose(s) (RP2D) of LVGN7409, both as a single agent (monotherapy) and in combination with a fixed dose of anti-PD-1 antibody and/or CD137 agonist in the treatment of advanced or metastatic malignancy.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/22/2023
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Cancer
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An Open-Label Study of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors
NCT04443088
Recruiting
Phase 1, open-label dose-escalation study to determine the MTD of INV-1120 and RP2D, and to assess the DLT of INV-1120 as a single agent or in the combination with pembrolizumab. The safety, tolerability, and PK of INV-1120 as a single agent or in the combination with pembrolizumab will be assessed in adult patients with advanced solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/19/2023
Locations: Horizon Oncology Research, LLC,, Lafayette, Indiana +2 locations
Conditions: Cancer, Solid Tumor, Adult, Cancer Metastatic, Solid Carcinoma, Solid Tumor, Unspecified, Adult, Tumor, Solid
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MCW Master Predict (Profile Related Evidence Determining Individualized Cancer Therapy)
NCT05802069
Recruiting
The study is an observational trial for patients undergoing cancer-related interventions and therapy at Medical College of Wisconsin Cancer Center. Projects under this protocol will use patient data that will be collected both retrospectively and prospectively. It will also enable prospective sample collection for specific cancer-related studies.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/16/2023
Locations: Froedtert Hospital and the Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Cancer
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Patient Navigation 2.0
NCT04234646
Recruiting
This study evaluates whether a "Patient Navigation 2.0 Checklist" intervention is effective in addressing patients' social determinants of health and recommended cancer-related screenings, behavioral counseling, and immunizations.
Gender:
All
Ages:
21 years and above
Trial Updated:
06/08/2023
Locations: Northwestern, Chicago, Illinois
Conditions: Cancer
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Improving Cancer Symptom Management
NCT04589247
Recruiting
Patient-reported outcome measures (PROMs) is an umbrella term that refers to any report on a health status measure that is reported directly by the patient, without the influence of clinicians or anyone else. PROMs have been shown to more closely reflect a patient's daily health status when compared to physician-reported measures. However, research is needed to evaluate if patient symptom reporting during definitive-intent radiotherapy allows earlier and improved detection of treatment toxicity.... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
05/30/2023
Locations: Bayview Medical Center, Baltimore, Maryland +3 locations
Conditions: Cancer, Thoracic Neoplasms, Gastrointestinal Cancer, Lung Cancer
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Symptom Management for Rural-Urban Cancer Survivors and Caregivers
NCT05360498
Recruiting
As the population of cancer survivors increases substantially, meeting the health care and psychosocial needs of this population has become a national priority. After treatment ends, cancer survivors still experience a range of physical and psychological symptoms that require management. The post-treatment period can present new challenges for many survivors as they encounter communication gaps in the transition from oncology to primary care, leaving unmet needs for information and management of... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/25/2023
Locations: University of Arizona, Tucson, Arizona
Conditions: Cancer, Cancer Survivors, Informal Caregivers, Psychological Distress
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enCompass Carolina: A Social Support and Coaching Program for Cancer Caregivers
NCT05828927
Recruiting
This study explores the feasibility, acceptability, and preliminary efficacy of a social support intervention in cancer caregivers who live in rural communities. Cancer caregivers need support, especially when they live at a distance from healthcare centers. enCompass Carolina is a social support intervention, that supports caregivers by helping them find and use new sources of support. The purpose of this study is to test and receive feedback about the program.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/23/2023
Locations: UNC Lineberger, Chapel Hill, North Carolina
Conditions: Cancer
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Evaluating the Implementation and Impact of Navigator-delivered ePRO System
NCT04809740
Recruiting
1) Evaluate implementation of navigator-delivered Home ePRO for all cancer patients across multiple practice sites; 2) examine the barriers, facilitators, and implementation strategies used in implementing navigator-delivered Home ePRO; and 3) assess the impact of Home ePRO on clinical and utilization outcomes.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama +1 locations
Conditions: Cancer
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Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers
NCT05823740
Recruiting
The primary objective of this study is to evaluate the feasibility and acceptability of obtaining repeated measurements of lean muscle mass, physical function, and biological aging in children receiving active cancer therapy. The secondary objective is to evaluate the feasibility of using the D3-creatine dilution method (D3Cr) to measure skeletal muscle mass in children with cancer. Assessments will be collected at diagnosis, once during active treatment, and end of treatment in coordination wi... Read More
Gender:
All
Ages:
Between 8 years and 21 years
Trial Updated:
05/15/2023
Locations: UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Conditions: Cancer, Malignant Neoplasm
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