There are currently 283 active clinical trials seeking participants for Cancer research studies. The states with the highest number of trials for Cancer participants are California, Texas, New York and Florida.
Effects of Oncological Treatment During Pregnancy on Mother and Child
Recruiting
The researchers aim to investigate the outcome (overall survival) of mothers who are diagnosed and/or treated for cancer during pregnancy. Furthermore they want to test the hypothesis that children who were exposed to cancer or cancer treatment (cytotoxic drugs, radiation therapy, targeted therapy,...) develop normally (neurologic and cardiologic examination).
Gender:
Female
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Cooper University Hospital (2015-ongoing), Camden, New Jersey +32 locations
Conditions: Cancer, Pregnancy
Resilience Mobile App for Teens and Young Adults With Cancer
Recruiting
The goal of this pilot trial is to examine whether a mobile app version of the Promoting Resilience in Stress Management (PRISM) intervention is acceptable, easy to use, and helps improve quality of life and mental health symptoms.
Gender:
All
Ages:
Between 12 years and 25 years
Trial Updated:
02/25/2024
Locations: Seattle Children's Hospital, Seattle, Washington
Conditions: Cancer
Avera Cancer Sequencing and Analytics Protocol (ASAP)
Recruiting
The purpose of this study is to understand the breadth of molecular characteristics present in participants cared for in a large integrated, community-based health care system. Using comprehensive genomic profiling and proteomics, the investigators seek to identify the underlying genomic drivers of premalignant or malignant conditions in participants across different stages of disease development and cancer types. Comprehensive molecular profiling will consist of somatic tumor testing (tissue a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/23/2024
Locations: Avera Cancer Institute - Aberdeen, Aberdeen, South Dakota +1 locations
Conditions: Cancer, Cancer Diagnosis, Early Detection of Cancer, Breast Cancer, Lung Cancer, Colon Cancer, GI Cancer, Gynecologic Cancer, Ovarian Cancer, Endometrial Cancer, CNS Cancer, Hematologic Cancer
Construal Level as a Novel Pathway for Affect Regulation and Cancer Control
Recruiting
The objective of the proposed research is to conduct a longitudinal experiment on the neurocognitive pathways and individual differences in high-level construal for affect regulation and smoking cessation. The population is adult smokers aged 25-55 who have tried and failed to quit and who are experiencing poverty. The primary endpoints are (a) the similarity in neural representation of high-level construal to one of two candidate pathways, (b) the presence of meaningful individual differences i... Read More
Gender:
All
Ages:
Between 25 years and 55 years
Trial Updated:
02/14/2024
Locations: University of Oregon, Lewis Integrative Sciences Building, Eugene, Oregon +1 locations
Conditions: Smoking Cessation, Smoking Reduction, Cancer
Mindful Waiting Room
Recruiting
This will be a single-site, five-arm, parallel group randomized control trial involving patients seeking integrative healthcare. Four different styles of 5-minute, audio-recoded mindfulness practices delivered in the clinic waiting room will be compared with a 5-minute audio-recording about integrative healthcare. A secondary sub-analysis will investigate the most effective mindfulness practice style for patients presenting at the clinic with elevated anxiety, depression, or pain.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/05/2024
Locations: University of Utah, Salt Lake City, Utah
Conditions: Anxiety State, Depressive State, Pain, Nausea, Fatigue, Cancer
A Study of NTX-1088, a Monoclonal Antibody Targeting the Poliovirus Receptor (PVR, CD155), as Monotherapy and Combined With Pembrolizumab
Recruiting
This is a Phase 1,open-label, multi-center, first-in-human, 2-part (Part 1: dose escalation and Part 2: expansion) study, evaluating multiple doses and schedules of intravenously (IV) administered NTX-1088, with or without pembrolizumab, in patients with advanced solid malignancies (i.e., locally advanced or metastatic).
Gender:
All
Ages:
18 years and above
Trial Updated:
01/25/2024
Locations: City of Hope, Duarte, California +4 locations
Conditions: Cancer, Tumor, Solid, Advanced Solid Tumor, Metastatic Cancer, Locally Advanced Solid Tumor
Autologous TLPO Vaccine Basket
Recruiting
The goal of this clinical trial is to learn about TLPO cancer vaccine in cases of solid tumor malignancies. The main objectives it aims to learn about are: What is the time to progression/recurrence of disease after vaccination with the autologous TLPO vaccine in multiple solid tumor malignancies? What is the overall survival after vaccination with the autologous TLPO vaccine in multiple solid tumor malignancies? What are the safety characteristics of autologous TLPO using standardized criteria... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/23/2024
Locations: Southside Medical Center, Greenville, South Carolina
Conditions: Tumor, Solid, Tumor Metastasis, Cancer, Tumor
mychoiceTM Implementation With Medical Oncology Patients
Recruiting
This is a pragmatic, non-randomized mixed-methods evaluation study designed to evaluate the feasibility and acceptability of delivering the mychoiceTM tool to new Medical Oncology patients as well as to more deeply explore its value to patients in their discussion with their provider about clinical trials as a treatment option over the course of their oncology treatment (Effectiveness).
Gender:
All
Ages:
18 years and above
Trial Updated:
01/22/2024
Locations: Fox Chase Cancer Center, Philadelphia, Pennsylvania
Conditions: Cancer
A Dose Finding Phase 1 of Sarilumab Plus Capecitabine in HER2/Neu-Negative Metastatic Breast Cancer and a Single-arm, Historically-controlled Phase 2 Study of Sarilumab Plus Capecitabine in Stage I-III Triple Negative Breast Cancer With High-Risk Residual Disease (EMPOWER)
Recruiting
This study looks to advance a novel and potent strategy to eliminate minimal residual disease (MRD) in triple negative breast cancer (TNBC) present even after multimodal treatment, thereby improving survival and increasing cure rate in this aggressive cancer. Patients with locally advanced TNBC are at high risk of developing lethal metastatic disease within 2 years of diagnosis, especially for those without a pathologic complete response (pCR) after neoadjuvant chemotherapy. The high risk occurs... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
01/16/2024
Locations: Los Angeles General Medical Center, Los Angeles, California +2 locations
Conditions: Breast, Metastatic, Triple Negative, Cancer, Disseminated Tumor Cell
Total Cancer Care Protocol: A Lifetime Partnership With Patients Who Have or May be at Risk of Having Cancer
Recruiting
The overall objective of this study is to ultimately develop an improved standard of cancer care by facilitating new cancer research, clinical trials, new technology, new informatics solutions, and "personalized medicine" for the University of New Mexico Comprehensive Cancer Center (UNMCCC) and the Oncology Research Information Exchange Network (ORIEN) Consortium of academic medical centers, community hospital systems, and other health care providers. To bring new translational research to the c... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/09/2024
Locations: University of New Mexico Comprehensive Cancer Center, Albuquerque, New Mexico
Conditions: Cancer, Cancer Risk
Vincere Biobank Research Protocol
Recruiting
The Vincere Biobank aims to make quality biospecimens and associated clinical data available for research studies related to advancing medicine and improving care for patients, including cancer screening, treatment, and care.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/06/2023
Locations: Vincere Cancer Center, Scottsdale, Arizona
Conditions: Cancer
Positron Emission Tomography (PET) Imaging of Thrombosis
Recruiting
The purpose of the study is to evaluate a new radiotracer called 64Cu-FBP8 for PET-MR imaging of thrombosis. The tracer has the potential of detecting thrombosis anywhere in the body, for instance in the left atrial appendage of patients with atrial fibrillation, and thereby may provide a non-invasive alternative to the current standard-of-care methods.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
12/01/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Atrial Fibrillation, COVID-19, Cancer, Thrombosis