There are currently 118 active clinical trials seeking participants for Dementia research studies. The states with the highest number of trials for Dementia participants are Florida, California, New York and Ontario.
Educational Support Group Program for Bilingual and Spanish-speaking Carepartners and People With Progressive Aphasia
NCT06511752
Recruiting
The current study aims to examine the benefits of an education/support group program for individuals with progressive aphasia (caused by various etiologies, diagnoses) and their carepartners. The current study utilizes pre-, post-treatment, and follow-up assessments to measure effects of a psychoeducational support group and an implementation/communication skills training phase on measures of psychosocial function, communicative effectiveness and speech/language function. Analysis of study-speci... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/27/2025
Locations: University of Texas at Austin, Austin, Texas
Conditions: Alzheimer Disease, Dementia, Primary Progressive Aphasia, Aphasia, Progressive Aphasia, Progressive Aphasia in Alzheimer's Disease
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A Study to Evaluate the Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia (MK-1167-008)
NCT06721156
Recruiting
Researchers want to learn if giving MK-1167 (the study medicine) along with acetylcholinesterase inhibitor (AChEI) therapy can improve symptoms of Alzheimer's disease dementia (AD dementia), such as memory and mental activity. AD dementia is the most common type of dementia. AChEI therapy is the standard treatment for AD dementia. The goals of this study are to learn: * If at least one dose level (amount) of MK-1167 works to improve a person's memory and thinking compared to a placebo * About... Read More
Gender:
ALL
Ages:
Between 55 years and 90 years
Trial Updated:
02/26/2025
Locations: California Neuroscience Research ( Site 0118), Sherman Oaks, California +21 locations
Conditions: Alzheimer Disease, Dementia
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Door-Through-Door Companion Rideshare Technology for Individuals with Alzheimer's Disease and Related Dementias (AD/ADRD)
NCT06850870
Recruiting
The goal of this pilot randomized controlled trial is to assess the impact of D2D rideshare services with a trained companion driver on the rate of medical appointments for older adults and individuals with AD/ADRD. Participants will be assigned either door-through-door (D2D) rideshare or curb-to-curb (C2C) rideshare services. he main question it aims to answer is: Do D2D rideshare services reduce missed medical appointment rates compared to C2C rideshare services?
Gender:
ALL
Ages:
60 years and above
Trial Updated:
02/24/2025
Locations: Onward Health HQ, San Leandro, California
Conditions: Alzheimer Disease or Associated Disorder, Dementia, Cognitive Decline
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Combating Alzheimer's Through Sleep and Exercise
NCT04855630
Recruiting
The purpose of this research is to see how sleep and exercise affects dementia risk over time.
Gender:
ALL
Ages:
Between 45 years and 80 years
Trial Updated:
02/21/2025
Locations: University of Miami Hospitals, Miami, Florida
Conditions: Alzheimer Disease, Dementia
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Primary Care Detection of Cognitive Impairment Leveraging Health & Consumer Technologies in Underserved Communities: The MyCog Trial
NCT05607732
Recruiting
Our study intends to offer 'real world' evidence of a viable, sustainable means to mobilize primary care via a comprehensive strategy for detecting cognitive impairment and dementias, advancing next steps for referral, and participating in the care planning and management of affected patients and caregivers. We will conduct a clinic-randomized, pragmatic trial testing the effectiveness and fidelity of our NIH Toolbox-derived paradigm to improve early detection and management of cognitive impairm... Read More
Gender:
ALL
Ages:
45 years and above
Trial Updated:
02/18/2025
Locations: Oak Street Health, Chicago, Illinois
Conditions: Dementia, Cognitive Impairment, Cognitive Decline, Alzheimer Disease
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ToolBox Detect: Low Cost Detection of Cognitive Decline in Primary Care Settings
NCT04852601
Recruiting
Our study objective is to widely implement and evaluate a user-centered, scalable, electronic health record (EHR)-linked strategy for the routine detection of cognitive decline among diverse primary care settings. This strategy, called ToolboxDetect, will provide an efficient and sensitive cognitive screen that can be easily implemented in everyday clinical settings, and is responsive to patient, family, and caregiver concerns for potential symptoms of cognitive decline (CD) and cognitive impair... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
02/18/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Cognitive Dysfunction, Dementia
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Community Health Worker-Led Transition Support for Persons Living With Dementia and Caregivers
NCT06831318
Recruiting
The main purpose of this intervention study is to test if the community health worker (CHW)-led care transition support intervention is feasible and acceptable to the persons living with dementia (PLWD)'s caregivers, and other healthcare providers. Main hypotheses of the study are: 1. the CHW interventionist will adhere to the intervention protocol with the score of 80% or higher on the intervention fidelity checklist throughout the intervention delivery period; 2. caregiver participants in th... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
02/14/2025
Locations: Dell Seton Medical Center, Austin, Texas
Conditions: Cognitive Impairment, Dementia, Memory Deficits
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Study to Understand Novel Biomarkers in Researching Dementia
NCT06547099
Recruiting
The purpose of this study is to determine the relationships between amyloid, tau, and neurodegeneration biomarkers in the blood and the presence of Alzheimer's disease (AD) pathology, clinical cognitive decline, and diagnosis. We aim to understand how well blood-based biomarkers can diagnose and predict Alzheimer's disease, which will help to further develop and validate blood tests for the disease.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
02/07/2025
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Alzheimer Disease, Mild Cognitive Impairment, Dementia
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Environmental and Sensory Intervention for Nursing Home Residents With Dementia Who Exhibit Persistent Vocalizations
NCT06568107
Recruiting
The purpose of this study is to test a person-centered, nature-based non-pharmacological intervention for nursing home residents living with dementia who exhibit persistent vocalizations. The Environmental And Sensory Experience (EASE) involves the projection of a still nature image and the playing of nature sounds. Family members of the person living with dementia provide consent for the resident to participate in the study and complete a brief survey on nature preferences on the resident's beh... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
02/05/2025
Locations: Drexel University, Philadelphia, Pennsylvania
Conditions: Dementia
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Developing a Communication Intervention for People With Memory Challenges and Their Care Partners
NCT05143255
Recruiting
The proposed research is consistent with broader public health goals focused on improving communication regarding end-of-life care and the Centers for Medicare and Medicaid Services' (CMS) call for increased patient engagement in advance care planning (ACP) as part of standard care. The proposed study will address this public health issue by developing a communication-based intervention designed to improve Alzheimer's Disease and Related Dementias (ADRD) patients' and care partners' engagement i... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/28/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Alzheimer Disease, Dementia
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Deprescribing Potentially Inappropriate Medications in the Emergency Department for Persons Living with Dementia
NCT06273917
Recruiting
Aim 1: To demonstrate the feasibility by determining proportion of completed medication reconciliation, Central Nervous System active Potentially Inappropriate Medication (CNS PIM) use among patients with Alzheimer's Disease and Related Dementias (ADRD) and Mild Cognitive Impairment (MCI) in the emergency department (ED), and communication between ED clinical pharmacists and outpatient prescribers. Aim 2: To demonstrate the feasibility of collecting the primary and secondary outcomes for a subs... Read More
Gender:
ALL
Ages:
Between 18 years and 120 years
Trial Updated:
01/23/2025
Locations: Northwestern Memorial Hospital, Chicago, Illinois +2 locations
Conditions: Dementia
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Home Alone: An Intervention for People With Cognitive Impairment Who Live Alone
NCT05746390
Recruiting
The goal of this clinical trial is to evaluate a program for adults who live alone and have some cognitive impairment (CI) to see if it is useful and acceptable. This program aims to help older adults with cognitive impairment who live alone to be engaged and active, as well as safe at home. The investigators want to see how useful this program is and how it can be improved. The specific aims are: * Specific Aim 1: Develop and Adapt Home Alone to Prepare for Pilot Testing. * Specific Aim 2: Pi... Read More
Gender:
ALL
Ages:
55 years and above
Trial Updated:
01/23/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Cognitive Impairment, Dementia, Memory Loss
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