There are currently 118 active clinical trials seeking participants for Dementia research studies. The states with the highest number of trials for Dementia participants are Florida, California, New York and Ontario.
Music Therapy and Social Work Telehealth for Older Adult Well-Being
Recruiting
This study investigates the benefits of using telehealth services, specifically a combination of music therapy and social work support, to improve the well-being of older adults. Investigators are focusing on outcomes such as reduced loneliness, improved cognition, and how well older adults with and without dementia perceive the quality of the services received. This research is crucial because as the population ages and conditions like Alzheimer's become more prevalent, effective psychosocial i... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
01/14/2025
Locations: University of Kentucky, Lexington, Kentucky +1 locations
Conditions: Aging Well, Dementia, Telemedicine
Quality Improvement and Clinical Utility PrecivityAD2(TM) Clinician Survey
Recruiting
There is a major unmet need for timely, non-invasive, and low-burden evaluation of patients presenting with mild cognitive impairment (MCI) and dementia. MCI impacts 12-18% of people in the United States over age 60 years (Alzheimer's Association. Mild Cognitive Impairment (MCI) available at https://www.alz.org/alzheimers-dementia/what-is-dementia/related_conditions/mild-cognitive-impairment. Accessed August 16, 2022). MCI does not substantially interfere with daily activities, although complex... Read More
Gender:
ALL
Ages:
55 years and above
Trial Updated:
01/13/2025
Locations: UCSF Memory and Aging Center, San Francisco, California +8 locations
Conditions: Alzheimer Disease, Mild Cognitive Impairment, Dementia, Cognitive Decline, Cognitive Impairment, Memory Impairment
Adapting the Shed-MEDS Deprescribing Intervention to Dementia Care in Assisted Living
Recruiting
This single-arm pilot study will evaluate the effects of an intervention to reduce exposure to unnecessary or potentially harmful medications among residents with dementia living in an assisted living facility. The goal of the intervention is to safely deprescribe medications (defined by dose reductions and stopped medications), based on a combination of clinical criteria and resident/surrogate preferences. The investigators will evaluate the effects of the intervention on the total number of me... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
01/07/2025
Locations: Abe's Garden Community, Nashville, Tennessee +1 locations
Conditions: Polypharmacy, Dementia, Quality of Life
Caregiver as Navigator: Develop Skills Online (CAN-DO)
Recruiting
This study is designed to learn more about ways to promote caregiver mastery online. 270 dementia family caregivers will be enrolled and randomized to take the CAN-DO online course immediately or after a waiting period. They will participate in interviews before and after the course; total time of study participation is 6 months.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/06/2025
Locations: Emory Roybal Center for Dementia Caregiving Mastery, Atlanta, Georgia
Conditions: Dementia
A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (Hope Study, CA-0011)
Recruiting
This is a randomized, double-blind, sham-controlled, adaptive-design pivotal study of sensory stimulation in subjects with mild to moderate Alzheimer's disease. Up to approximately 600 subjects will be randomized to 12 months of daily treatment with either Active or Sham Sensory Stimulation Systems. Efficacy will be measured using the Alzheimer's Disease Cooperative Study- Activities of Daily Living (ADCS-ADL) assessment and a combined statistical test (CST) of the ADCS-ADL and the Mini-Mental S... Read More
Gender:
ALL
Ages:
Between 50 years and 90 years
Trial Updated:
01/06/2025
Locations: CCT Research - Gilbert Neurology Partners, Gilbert, Arizona +67 locations
Conditions: Alzheimer Disease, Alzheimer Disease 1, Alzheimer Disease 2, Alzheimer Disease 3, Alzheimer Disease, Early Onset, Alzheimer Disease, Late Onset, Alzheimer Disease 9, Alzheimer Disease 4, Alzheimer Disease 7, Alzheimer Disease 17, Alzheimer's Dementia Late Onset, Alzheimer Disease 5, Alzheimer Disease 6, Alzheimer Disease 8, Alzheimer Disease 10, Alzheimer Disease 11, Alzheimer Disease 12, Alzheimer Disease 13, Alzheimer Disease 14, Alzheimer Disease 15, Alzheimer Disease 16, Alzheimer Disease 18, Alzheimer Disease 19, Dementia, Dementia Alzheimers, Dementia, Mild, Dementia of Alzheimer Type, Dementia Moderate, Dementia Senile, Mild Cognitive Impairment, Mild Dementia, MCI, Cognitive Impairment, Cognitive Decline, Cognitive Impairment, Mild
A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors
Recruiting
Up to 25% of intensive care unit (ICU) survivors experience cognitive impairment comparable in severity to mild Alzheimer's disease and related dementias after hospital discharge. Older ICU survivors (ages 60 and older) are at highest risk for delirium and subsequent cognitive impairment, which contribute to higher risk for cognitive decline related to Alzheimer's disease and related dementias. Sleep and activity are essential for recovery from critical illness, yet ICU survivors experience both... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
12/27/2024
Locations: University of Washington, Seattle, Washington
Conditions: Critical Illness, Delirium, Cognitive Impairment, Cognitive Decline, Alzheimer's Disease, Dementia, Circadian Dysrhythmia, Sleep Disturbance
Family Caregiver Online Survey (Dementia and Swallowing Difficulties)
Recruiting
The Family Caregiver Survey is a one-time, 30-minute, online survey for people living with and caring for a family member with dementia. The goal of this research is to explore the needs of family caregivers, specifically when it comes to managing swallowing difficulties (dysphagia).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/13/2024
Locations: Remote study offered by the University of Oregon, Eugene, Oregon
Conditions: Dementia, Dysphagia, Dementia Alzheimers, Dementia, Vascular, Dementia, Mixed, Dementia With Lewy Bodies, Dementia Frontal, Dementia, Mild, Dementia Moderate, Dementia Severe, Parkinson Disease Dementia, Dementia Frontotemporal
Enhancing Health and Quality of Life for Individuals With Dementia Through Transitional-State Snacks
Recruiting
Malnutrition significantly contributes to the disability and mortality associated with Alzheimer's disease and Alzheimer's disease-related dementias. Thus, nutritional status is one important, modifiable clinical factor for maintaining physical and cognitive health among persons with dementia (PWD). This project will pilot an innovative approach to enhancing nutrition through the use of transitional-state snack supplements, or foods that start as one texture and change to another. Specifically,... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/13/2024
Locations: University of Oregon, Eugene, Oregon +1 locations
Conditions: Dementia, Nutrition Poor
Testing the Pain Clinical Practice Guideline
Recruiting
There are evidence based processes for assessment and management of pain using pharmacologic and nonpharmacological approaches. These were reviewed and included within the Pain Management Clinical Practice Guideline (Pain Management CPG) recently developed by AMDA: The Society for Post-Acute and Long-Term Care Medicine. There are, however, many challenges to translating the use of Clinical Practice Guidelines into clinical settings. To overcome these challenges we developed and previously tested... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
12/11/2024
Locations: Future Care Coldspring, Baltimore, Maryland +4 locations
Conditions: Pain, Dementia
A Technology-Driven Intervention to Improve Early Detection and Management of Cognitive Impairment
Recruiting
Most experts advocate for early detection of cognitive impairment (CI) so that patients and caregivers can be prepared for making difficult decisions and to improve quality of life, but studies show that screening alone isn't sufficient to change clinician actions related to early detection. Using predictive modelling developed with machine learning methods and sophisticated clinical decision support (CDS) tools, it is possible to identify patients at elevated risk for CI and make it much easier... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
12/10/2024
Locations: HealthPartners, Bloomington, Minnesota +1 locations
Conditions: Dementia, Cognitive Impairment
HEARS-SLP: Providing SLP-Delivered Hearing Health Care to Individuals With Cognitive Impairment
Recruiting
Building upon the HEARS audiologist-community health worker (CHW) model, this study intervention will be delivered by a speech-language pathologist (SLP). The primary objective of the study is to develop and test an affordable and accessible hearing rehabilitative intervention that will be delivered by a SLP to individuals with cognitive impairment.
Gender:
ALL
Ages:
Between 60 years and 100 years
Trial Updated:
12/05/2024
Locations: Johns Hopkins Medicine, Baltimore, Maryland
Conditions: Hearing Loss, Dementia, Cognitive Impairment
The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia
Recruiting
Older adults at risk for dementia show a variety of cognitive deficits, which can be ameliorated by different cognitive training (CT) exercises. The best combination of CT exercises is unknown. The aim is to discover the most efficacious combination of CT exercises as compared to cognitive stimulation (which will serve as a stringent, active control) to modify the functional trajectories of older adults' with MCI, who are at high risk for dementia. The primary objective of the U01 phase was to d... Read More
Gender:
ALL
Ages:
Between 55 years and 89 years
Trial Updated:
12/05/2024
Locations: University of California San Francisco, San Francisco, California +3 locations
Conditions: Age-related Cognitive Decline, Mild Cognitive Impairment, Dementia