Maryland is currently home to 2674 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Baltimore, Bethesda, Rockville and Annapolis. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Covid-19 Long Haul Preventative and Health Promotion Care Clinical Trial Acceleration Program.
NCT06441955
Recruiting
Investigators are conducting a study on alternative treatments for patients who have received an current or previous positive COVID-19 diagnosis with mild-serve symptoms or undiagnosable condition after testing positive for severe acute COVID-19 infection and are experiencing long-haul symptoms. The symptoms of long COVID can include extreme tiredness (fatigue), shortness of breath, memory and concentration issues (brain fog), heart palpitations, dizziness, joint pain, muscle aches, cough, heada... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/24/2024
Locations: NIH Clinical Center, Bethesda, Maryland
Conditions: COVID-19, Long Haul
Register for Updates
Is Physical Therapy Clearance Before Arthroplasty Home Discharge Necessary?
NCT05858086
Recruiting
Conventionally, physical therapy (PT) clearance is sought before total joint arthroplasty (TJA) discharge. However, PT staffing limitations may preclude same-day discharge in patients having surgery late in the day. Failed same-day discharge in eligible TJA patients results in unnecessary hospital bed occupancy, which increases costs, limits operating room throughput for patients requiring inpatient admission, and introduces risks associated with longer length-of-stay. In collaboration with an... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
11/23/2024
Locations: University of Maryland, Baltimore, Maryland
Conditions: Physical Therapy, Total Joint Arthroplasty, Same-day Discharge
Register for Updates
Proper Duration of Suppressive Antibiotic Therapy After Debridement, Antibiotics, and Implant Retention
NCT05495815
Recruiting
Multiple studies have demonstrated oral suppressive antibiotic therapy (SAT), after intravenous antibiotics, maximizes reoperation-free survival of total joint arthroplasty (TJA) debridement, antibiotics, and implant retention (DAIR) for acute periprosthetic joint infection (PJI). However, little is known regarding sequelae of SAT after DAIR for PJI. Prior studies have small or heterogeneous patient cohorts, variable antibiotic regimens, arrive at disparate conclusions, and do not establish anti... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/23/2024
Locations: University of Maryland, Baltimore, Maryland
Conditions: Periprosthetic Joint Infection, Antibiotic Suppression
Register for Updates
Enhancing Care & Outcomes for Patients During the First Postpartum Year
NCT06615076
Recruiting
The United States is in the midst of a maternal mortality and morbidity crisis, with more than half of maternal deaths occurring within the first postpartum year. Patients with hypertensive disorders of pregnancy (HDP) and diabetes have been found to be particularly high-risk, as they have a significantly increased risk for the development of cardiovascular disease in the long-term postpartum period. Traditionally, postpartum care has consisted of a single office visit at six weeks postpartum. R... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
11/22/2024
Locations: University of Maryland, Baltimore, Baltimore, Maryland
Conditions: Postpartum Period, Pregnancy, Hypertension, Pregnancy Induced
Register for Updates
Development and Evaluation of a PrEP Decision Aid for Women Seeking Domestic Violence Services in Baltimore
NCT05614492
Recruiting
This study is designed to develop and test an individual decision aid for pre-exposure prophylaxis (PrEP) tailored to Black women who have been exposed to intimate partner violence and are working with a domestic violence service provider. three different ways of delivering the tailored decision aid are being tested: 1) as an individual tool; or 2) as a shared decision-making tool with a domestic violence advocate; as compared to generalized information. The goal of decision aid will be to addre... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
11/22/2024
Locations: Springboard Community Services - Baltimore City Office, Baltimore, Maryland
Conditions: HIV, Violence, Gender-Based, Pre-Exposure Prophylaxis
Register for Updates
Targeting Emotion Dysregulation to Reduce Suicide in People with Psychosis
NCT05440214
Recruiting
People with psychotic disorders are excluded from most suicide-focused clinical trials despite incredibly high rates of completed suicide, and interventions that have been tested for this population have shown limited impact on suicide. Emotion dysregulation is a significant suicidogenic factor that is understudied in people with psychotic disorders. The investigators propose to implement and evaluate an intervention targeting emotion dysregulation in people with psychotic disorders while employ... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/22/2024
Locations: University of Maryland, Baltimore, Maryland
Conditions: Psychosis, Suicide
Register for Updates
Pilot Study to Investigate Magnetic Resonance (MR) Image Guided Focal Therapy in Prostate Cancer
NCT04808427
Recruiting
Background: The ability to treat early prostate cancer is still limited. Thermal ablation methods are being tested for focal prostate cancer therapy. Researchers want to improve on these methods. Objective: To understand if Transurethral UltraSound Ablation (TULSA) in combination with MRI guidance is useful to treat localized prostate cancer. Eligibility: English-speaking adults ages 18 and older with localized prostate cancer that can be seen on MRI and can be treated by thermal ablation.... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
11/22/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Prostate Cancer
Register for Updates
A Study To Learn About Two Study Medicines (PF-07275315 And PF-07264660) In People Who Have Moderate To Severe Atopic Dermatitis
NCT05995964
Recruiting
The purpose of this study is to learn about the safety and effects of 2 study medicines (PF-07275315 and PF-07264660) for the treatment of atopic dermatitis (AD). AD is a long- lasting itchy red rash, caused by a skin reaction. This study is seeking participants who: * are 18 years of age or more. * Were confirmed to have AD at least 6 months ago. * Are not having an effective treatment result from medicines that are applied on skin for AD. * Are considered by their doctors to have moderate to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Maryland Laser Skin and Vein, Hunt Valley, Maryland
Conditions: Atopic Dermatitis
Register for Updates
DCSZ11 as a Monotherapy and in Combination in Patients With Advanced or Metastatic Solid Tumors
NCT05785754
Recruiting
This is a multicenter, open-label, Phase 1 study to assess the effects of DCSZ11, an anti-CD93 monoclonal antibody, as a monotherapy and in combination in patients with advanced or metastatic solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: John Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland
Conditions: Advanced or Metastatic Solid Tumors
Register for Updates
Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells
NCT05705024
Recruiting
The proposed Conventional Cohort Expansion Study involves the use of Mesenchymal Stromal Cells (MSCs) are derived from the bone marrow. We previously studied the safety of subconjunctival injection of allogeneic bone marrow-derived MSCs in patients with nonhealing epitheliopathy (IRB Protocol 2020-0334). In the present study, we want to study the efficacy of this treatment on chronic epitheliopathies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: University of Maryland at Baltimore, Baltimore, Maryland
Conditions: Corneal Ulcer
Register for Updates
A Study of Photobiomodulation (PBM) Therapy in People with Oral Graft-Versus-Host Disease (GVHD) After Stem Cell Transplant
NCT05675930
Recruiting
The purpose of this study is to find out whether photobiomodulation/PBM therapy using the Thor LX2.3 therapy system is a safe and effective treatment for oral Graft-Versus-Host Disease/GVHD.
Gender:
ALL
Ages:
4 years and above
Trial Updated:
11/21/2024
Locations: National Institute of Health (Data Collection AND Specimen Analysis), Bethesda, Maryland
Conditions: Graft-Versus-Host Disease, GVHD, Undefined
Register for Updates
Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)
NCT05354141
Recruiting
To evaluate the safety and efficacy of intravenous (IV) administration of bone marrow mesenchymal stem cell derived extracellular vesicles (EVs), ExoFlo, versus placebo for the treatment of hospitalized patients with moderate-to-severe Acute Respiratory Distress Syndrome (ARDS).
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
11/21/2024
Locations: Direct Biologics Investigational Site, Silver Spring, Maryland
Conditions: Acute Respiratory Distress Syndrome, ARDS
Register for Updates