Maryland is currently home to 2751 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Baltimore, Bethesda, Rockville and Annapolis. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Project PEER: Understanding the Lung Cancer Patient ExperiEnce in the Real-World Setting
NCT05826756
Recruiting
LUNGevity Foundation, a non-profit lung cancer organization, wants to learn about living with lung cancer from the point of view of people with lung cancer and their family and friends who provide care. To do this, we have an online study designed to better understand how treatments people living with lung cancer receive impact their quality of life. Participants will complete surveys once a month for 12 months. What does participation involve? Emailing the study team to learn more and get acc... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/26/2023
Locations: LUNGevity Foundation, Bethesda, Maryland
Conditions: Lung Cancer Patients, Caregivers
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Synbiotic Compound to Reduce Symptoms of Schizophrenia
NCT04226898
Recruiting
The purpose of this study is to determine if taking a synbiotic supplement versus a placebo will reduce symptoms of schizophrenia when used in addition to standard antipsychotic medications.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/19/2023
Locations: Sheppard Pratt Health System, Baltimore, Maryland
Conditions: Schizophrenia, Schizoaffective Disorder
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Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients
NCT03127267
Recruiting
The objective is to compare the efficacy and safety of masitinib in combination with riluzole versus matched placebo in combination with riluzole for the treatment of Amyotrophic Lateral Sclerosis (ALS).
Gender:
All
Ages:
Between 18 years and 81 years
Trial Updated:
04/14/2023
Locations: Johns Hopkins Medicine Brain Science Institute, Baltimore, Maryland
Conditions: Amyotrophic Lateral Sclerosis
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Biomarker Cost-Benefit Analysis of EFNEP
NCT05558085
Recruiting
The goal of this integrated project is to assess whether EFNEP is a cost-effective nutrition education intervention that generates sustained improvement in chronic disease biomarkers. This project will be unique in its use of objective biomarkers, instead of self-reported behaviors, to quantify the economic benefits generated by EFNEP through chronic disease prevention. A paired location untreated control group quasi-experimental design will be employed, with biomarkers (BMI, blood pressure, HbA... Read More
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
04/11/2023
Locations: University of Maryland, College Park, Maryland
Conditions: Chronic Disease
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BP1001-A in Patients With Advanced or Recurrent Solid Tumors
NCT04196257
Recruiting
This is a phase I, open-label, study of BP1001-A in participants with advanced or recurrent solid tumors. The dose escalation phase will determine the safety and the maximum tolerated dose (MTD) or maximum administered dose (MAD) of BP1001-A as a single agent. After the MTD or MAD of BP1001-A is established, the dose expansion phase will commence and determine the safety, toxicity and response of BP1001-A in combination with paclitaxel.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/27/2023
Locations: Holy Cross Hospital, Silver Spring, Maryland
Conditions: Solid Tumor, Adult, Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Endometrial Cancer, Peritoneal Cancer, Solid Tumor
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Gastrointestinal Microbiome Study of Appendiceal Cancer
NCT02599116
Recruiting
This study analyzes the gastrointestinal microbiome of appendiceal cancer patients with peritoneal spread scheduled to undergo cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC). Participants will provide fecal samples pre- and post-operatively.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
03/24/2023
Locations: Mercy Medical Center, Baltimore, Maryland
Conditions: Pseudomyxoma Peritonei, Appendiceal Neoplasm, Cancer, Appendiceal
Register for Updates
The PCOS Challenge Study
NCT05797909
Recruiting
The primary purpose of The PCOS Challenge Study will be to conduct high-quality research where patients are included in the design, and answering the questions that patients identify as important to their lived experience with PCOS. In partnership with clinical investigators, patients will work on the development and management of data collection, the research agenda, and the sharing of research findings. The PCOSC Study will promote the advancement of research that provides reliable, useful, an... Read More
Gender:
Female
Ages:
Between 12 years and 80 years
Trial Updated:
03/22/2023
Locations: PCOS Challenge: The National Polycystic Ovary Syndrome Association, Bethesda, Maryland
Conditions: Polycystic Ovary Syndrome
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LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis
NCT02205762
Recruiting
The LCH-IV is an international, multicenter, prospective clinical study for pediatric Langerhans Cell Histiocytosis LCH (age < 18 years).
Gender:
All
Ages:
18 years and below
Trial Updated:
03/21/2023
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Langerhans Cell Histiocytosis
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Ortho-R® for Rotator Cuff Repair Compared With Standard of Care Rotator Cuff Repair Without Ortho-R®
NCT05333211
Recruiting
Phase I/II, multi-center, prospective, blinded 2arm, parallel design and randomized controlled study. Assessing the Ortho-R/PRP combination and standard of care for rotator cuff repair, will be compared though 12 months.
Gender:
All
Ages:
Between 40 years and 75 years
Trial Updated:
03/17/2023
Locations: Johns Hopkins University, Columbia, Maryland
Conditions: Rotator Cuff Tears
Register for Updates
Evaluation of Performance of the LumiraDx Influenza A/B + RSV Test at POC Testing Sites
NCT04288921
Recruiting
A Multicenter Study Conducted to Evaluate the Performance of the LumiraDx Influenza A/B + RSV Test at Point of Care Testing Sites
Gender:
All
Ages:
All
Trial Updated:
03/10/2023
Locations: Gvozden Pediatrics, Millersville, Maryland
Conditions: Influenza, Human, Respiratory Syncytial Virus Infections
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SAD and MAD of Inhaled AR-501 in Health Adults and P. Aeruginosa Infected Cystic Fibrosis Subjects
NCT03669614
Recruiting
This is a Phase 1/2a randomized, double-blind, two-part, dose-ascending, multicenter study of AR-501 (gallium citrate) solution, administered via inhalation, in healthy adult and P. aeruginosa infected cystic fibrosis (CF) subjects. Phase 1 of the study in HV subjects will consist of a single-ascending-dose (SAD) cohort, followed by the HV multiple-ascending-dose (MAD) cohort. Phase 2a of the study in CF subjects will consist of a MAD study design. The study will evaluate the safety and pharmaco... Read More
Gender:
All
Ages:
Between 18 years and 49 years
Trial Updated:
03/07/2023
Locations: Research Site, Baltimore, Maryland
Conditions: Cystic Fibrosis
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Imipenem/Cilastatin-XNW4107 Versus Imipenem/Cilastatin/Relebactam for Treatment of Participants With Bacterial Pneumonia (XNW4107-302, REITAB-2)
NCT05204563
Recruiting
This study aims to compare treatment with Imipenem/Cilastatin-XNW4107 (IMI-XNW4107) with imipenem/cilastatin/relebactam (IMI/REL) in participants with hospital-acquired or ventilator-associated bacterial pneumonia (HABP or VAPB, respectively). The primary hypothesis is that IMI-XNW4107 is non-inferior to IMI/REL in all-cause mortality.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/06/2023
Locations: University of Maryland Medical Center, Baltimore, Maryland
Conditions: Hospital Acquired Bacterial Pneumonia or Ventilator-Associated Bacterial Pneumonia
Register for Updates