Maryland is currently home to 2682 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Baltimore, Bethesda, Rockville and Annapolis. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Connect® Myeloid Disease Registry
NCT01688011
Recruiting
The purpose of the Connect® Myeloid disease registry is to provide unique insights into treatment decisions and treatment patterns as they relate to clinical outcomes of patients with myeloid diseases in routine clinical practice. This disease registry will also evaluate molecular and cellular markers that may provide further prognostic classification which may or may not be predictive of therapy and clinical outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: Weinberg Cancer Institute at Franklin Square, Baltimore, Maryland
Conditions: Myelodysplastic Syndromes, Primary Myelofibrosis, Leukemia, Myeloid, Acute
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Tender Loving Care for Recurrent Pregnancy Loss
NCT06182878
Recruiting
The goal of this investigational study is to evaluate participation in a weekly, interactive, tender loving care messaging platform impact on pregnancy outcomes in patients with recurrent pregnancy loss. The main questions it aims to answer are: (1) does participation in weekly, interactive tender loving care messages increase live birth rates in patients with recurrent pregnancy loss? (2) Does participation in weekly, interactive tender loving care messages increase patients' quality of life?... Read More
Gender:
FEMALE
Ages:
Between 18 years and 44 years
Trial Updated:
04/29/2024
Locations: Walter Reed National Military Medical Center, Bethesda, Maryland
Conditions: Recurrent Pregnancy Loss
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Imaging Post-Stroke Recovery: Using MEG to Evaluate Cognition
NCT04188522
Recruiting
This is a study using magnetoencephalography (MEG) to look at recovery in those with minor stroke. The investigators know that these individuals report difficulties in attention, concentration, multi-tasking, energy level, and processing speed that appear to be independent of lesion size or location. The underlying pathophysiology is unclear; however, anecdotally, many individuals are significantly improved by 6 months post-stroke. One hypothesis is that a single lesion, regardless of size, may... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
04/29/2024
Locations: Johns Hopkins Bayview Medical Center, Baltimore, Maryland
Conditions: Stroke, Stroke Sequelae, Stroke/Brain Attack
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A Study of RGLS8429 in Patients With Autosomal Dominant Polycystic Kidney Disease
NCT05521191
Recruiting
Primary Objectives * To assess the safety and tolerability of RGLS8429 * To assess the impact of RGLS8429 on ADPKD biomarkers Secondary Objectives * To assess the impact of RGLS8429 on height-adjusted total kidney volume (htTKV) * To characterize the pharmacokinetic (PK) properties of RGLS8429 * To assess the impact of RGLS8429 on renal function
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
04/27/2024
Locations: University of Maryland School of Medicine, Nephrology, Baltimore, Maryland
Conditions: Autosomal Dominant Polycystic Kidney Disease, ADPKD, Polycystic Kidney, Autosomal Dominant
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[Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application
NCT05458544
Recruiting
Phase 1: The objective of the Phase 1 part of the clinical trial is to verify safety and tolerability (dose-limiting toxicity \[DLT\], maximum tolerated dose \[MTD\]) of a single 3.7 Giga-Becquerel (GBq) dose with the potential for one dose level de-escalation to 2.775 GBq if necessary, to determine the recommended \[177Lu\]Ludotadipep dose for use in the Phase 2a part of the trial. Phase 2a: The objective of the Phase 2a part of the trial is to evaluate safety and efficacy for repeated adminis... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
04/25/2024
Locations: University of Maryland, Baltimore, Maryland
Conditions: Metastatic Castration-resistant Prostate Cancer
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Phase 2 Trial of HY209gel in Atopic Dermatitis Patients
NCT06024499
Recruiting
This is a randomized, double-blind, placebo-controlled, multi-center, phase 2 study in patients with mild to moderate Atopic Dermatitis(AD), which consists of 2 parts.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
04/24/2024
Locations: Continental Clinical Solutions, LLC, Towson, Maryland
Conditions: Atopic Dermatitis, Atopic Dermatitis Eczema, Atopic Dermatitis of Scalp
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Computer Monitor vs Augmented Reality 3MDR for PTSD PTSD: A Randomized Controlled Trial
NCT05244564
Recruiting
This is a prospective randomized controlled trial comparing two ways of delivering Motion-assisted, Multi-modular Memory Desensitization and Reconsolidation (3MDR) therapy for posttraumatic stress disorder (PTSD). The study seeks 60 volunteers who have PTSD and are eligible for care in the Department of Defense healthcare system. There will be 10-14 therapy sessions that are 60-90 minutes long, about once a week, and symptoms will be assessed before and after the therapy as well as 3 and 6 month... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: Uniformed Services University, Bethesda, Maryland
Conditions: Stress Disorders, Post-Traumatic
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Systems Biology of Early Atopy
NCT04798079
Recruiting
The goal of this study is to establish a birth cohort that collects prenatal and early life biosamples and environmental samples and rigorously phenotypes young children for food allergy and Atopic Dermatitis (AD) to identify prenatal and early life markers of high risk for food allergy and AD, as well as biological pathways (endotypes) that result in these conditions. Primary Objectives: * To study the role and interrelationships of established and novel clinical, environmental, biological, a... Read More
Gender:
ALL
Ages:
0 years and above
Trial Updated:
04/23/2024
Locations: Johns Hopkins Children's Center, Department of Allergy & Immunology, Baltimore, Maryland
Conditions: Allergic Diseases, Food Allergy, Atopic Dermatitis
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Acoustic Stimulation During Restricted Sleep After Sleep Deprivation
NCT05309473
Recruiting
The purpose of this study is to determine if brief sounds or tones presented within a restricted period of recovery sleep after a period of sleep deprivation will enhance restorative properties and improve performance during a subsequent period of wakefulness.
Gender:
ALL
Ages:
Between 18 years and 39 years
Trial Updated:
04/22/2024
Locations: Walter Reed Army Institute of Research, Silver Spring, Maryland
Conditions: Sleep Deprivation, Sleep Restriction, Acoustic Stimulation, Performance, Alertness
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High-Risk Metachronous Oligometastatic Prostate Cancer Trial
NCT06212583
Recruiting
The purpose of this research study is to compare the effects, good and/or bad, of using the standard of care treatment, hormonal therapy + Stereotactic Ablative Radiation (SABR) to the metastatic lesions, compared to standard of care and addition of 6-months of niraparib/abiraterone acetate combination pills and prednisone for participants with recurrent metastatic prostate cancer.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
04/19/2024
Locations: University of Maryland Greenebaum Cancer Center, Baltimore, Maryland
Conditions: Prostate Cancer, Oligometastatic Disease
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Hyperpolarized 13C-pyruvate Metabolic MRI With Traumatic Brain Injury
NCT06103201
Recruiting
The purpose of this study is to examine the safety and feasibility of using hyperpolarized metabolic MRI to study early brain metabolism changes in subjects presenting with head injury and suspected non-penetrating traumatic brain injury (TBI). This study will also compare HP pyruvate MRI-derived metrics in TBI patients with healthy subjects as well as Subarachnoid hemorrhage (SAH) patients to better understand if metabolic Magnetic resonance imaging scan (MRI) can improve our ability to diagnos... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
04/19/2024
Locations: University of Maryland Baltimore, Baltimore, Maryland
Conditions: Traumatic Brain Injury, Subarachnoid Hemorrhage
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Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)
NCT06088381
Recruiting
Patients with human papillomavirus (HPV)-related oropharyngeal cancer generally have favorable outcomes and how well they do depends on the specific details about the patient and their cancer. How well they do isn't as related to the kinds of treatment they get. However, there are significant side effects for the various types of treatments they may get. Because these patients generally have favorable outcomes no matter the kind of treatment, reducing side effects should be a priority when choos... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/19/2024
Locations: Maryland Proton Treatment Center, Baltimore, Maryland
Conditions: Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Oropharynx Cancer, Oropharynx Squamous Cell Carcinoma, HPV Positive Oropharyngeal Squamous Cell Carcinoma
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