Maryland is currently home to 2680 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Baltimore, Bethesda, Rockville and Annapolis. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
2177GCCC:ID'Ing tx Targets and Biomarkers for Ocular Surface Disease in Pt w/ oGVHD
NCT04946721
Recruiting
Evaluate and study the immunologic changes to the ocular surface in cancer patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/01/2024
Locations: Geenebaum Cancer Center, University of Maryland Medical Center, Baltimore, Maryland
Conditions: Dry Eye Disease, oGVHD
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Phase I Study of ICP-332 in Healthy Subjects
NCT06530966
Recruiting
A multiple ascending dose phase I study of ICP-332 in healthy subjects
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
07/31/2024
Locations: Pharmaron CPC Inc., Baltimore, Maryland
Conditions: Healthy Subjects
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Multicenter HomeVENT: Home Values and Experiences Navigation Track
NCT06102330
Recruiting
This is a multicenter study to test a decision-making support process for families and clinicians facing decisions about chronic home ventilation for a child. The investigators hypothesize that the intervention will increase family preparedness for decision-making and will improve clinician-family shared-decision making. Half of families will be assigned to "usual care" arm and half to the "intervention" arm. Intervention families will view the study website with study staff and will answer ques... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/31/2024
Locations: Johns Hopkins University School of Medicine, Baltimore, Maryland
Conditions: Pediatric ALL, Respiratory Insufficiency, Communication
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Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)
NCT05546580
Recruiting
Iadademstat is being studied as a treatment for subjects with Relapsed or Refractory Acute Myeloid Leukemia (R/R AML) with FMS-like tyrosine kinase mutation (FLT3 mut+). During the trial, iadademstat will be given in combination with gilteritinib, a drug that is already approved to treat patients with FLT3-mutated R/R AML.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/26/2024
Locations: The John Hopkins University School of Medicine, Baltimore, Maryland
Conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory
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Intrahepatic and Peripheral Responses to Imdusiran (AB-729) in Chronic Hepatitis B
NCT06154278
Recruiting
The goal of this clinical trial is to learn about the action of Imdusiran (AB-729) in the liver of people with chronic hepatitis B. The main questions it aims to answer are: * how well is it working in the liver * how does Imdusiran affect the hepatitis B virus Participants will receive injections of Imdusiran, one injection every 8 weeks, for a total of 4 doses. They will also undergo 2 liver biopsies: one with the first dose of Imdusiran, and the second 8 weeks after the last dose of Imdusir... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2024
Locations: Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland
Conditions: Chronic Hepatitis B
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ABTECT-2 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -2
NCT05507216
Recruiting
This is a multicenter, randomized, placebo controlled study to evaluate the efficacy and safety of ABX464 given at 25 or 50 mg QD in inducing clinical remission in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies \[corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)\] and/or advanced therapies \[biologics (TNF inhibitors, anti-integrin... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
07/25/2024
Locations: University of Maryland Medical Center, Baltimore, Maryland
Conditions: Ulcerative Colitis
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A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome
NCT05804669
Recruiting
A Phase 1b/2a, first-in-disease, open-label, multiple-ascending dose exploratory study to evaluate safety, tolerability, pharmacokinetics (PK), and pharmacodynamic biomarker responses associated with CRN04894 (an adrenocorticotropic hormone \[ACTH\] receptor antagonist) in participants with ACTH-dependent Cushing's syndrome (Cushing's disease or Ectopic ACTH Syndrome \[EAS\])
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/24/2024
Locations: National Institutes of Health (NIH) - National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Bethesda, Maryland
Conditions: Cushing Syndrome, Cushing Disease, Ectopic ACTH Syndrome
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Investigation on the Bidirectional Cortical Neuroprosthetic System
NCT03161067
Recruiting
The Bidirectional Cortical Neuroprosthetic System (BiCNS) consists of NeuroPort Microelectrode Array Systems and NeuroPort Electrodes (Sputtered Iridium Oxide Film), Patient Pedestals, the NeuroPort BioPotential Signal Processing System, and the CereStim C96 Programmable Stimulator. The goals of this early feasibility study consist of safety and efficacy evaluations of this device.
Gender:
ALL
Ages:
Between 22 years and 65 years
Trial Updated:
07/24/2024
Locations: Department of Neurology, Baltimore, Maryland
Conditions: Tetraplegia, Quadriplegia
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A Novel Device for Neck Pain in Active-duty Military Personnel With Forward Head Posture.
NCT05433025
Recruiting
Neck pain is a common complaint among active duty military personnel, and can have tremendous impacts on quality of life and participation in duty-related activities. Treatments for spinal pain in military personnel are typically multimodal, relying upon physical therapy, pharmacological agents, spinal manipulation, and psychotherapy. However, there does not exist a wide body of evidence to support many of these treatments in active-duty military. The Cervigard neck collar was designed to treat... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
07/23/2024
Locations: Walter Reed National Military Medical Center, Bethesda, Maryland
Conditions: Neck Pain
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Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating Gliomas
NCT04772456
Recruiting
The purpose of this study is to examine the safety and feasibility of performing hyperpolarized metabolic MRI in the diagnosis of brain tumor. This study will also assess the accuracy of hyperpolarized metabolic MRI to diagnose intermediate to patients with infiltrating gliomas and examine the added utility of metabolic MRI over standard MRI imaging The FDA is allowing the use of hyperpolarized \[1-13C\] pyruvate (HP 13C-pyruvate) in this study. Up to 5 patients may take part in this study at... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
07/18/2024
Locations: Rosy Njonkou Tchoquessi, Baltimore, Maryland
Conditions: Glioma
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MYLUNG Consortium Part 3: Observational Study
NCT05885698
Recruiting
This longitudinal study looks to quantify the testing timeline, operational barriers, and outcomes of biomarker-guided therapy in a large, community-based, and largely unselected patient population with early stage and advanced stage, treatment-naive non-small cell lung cancer, whether squamous or non-squamous.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/17/2024
Locations: Maryland Oncology Hematology, P.A., Silver Spring, Maryland
Conditions: Carcinoma, Non-Small-Cell Lung
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Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow
NCT04254185
Recruiting
This research is studying two surgical procedures in a large group of people to learn about how well these procedures work as a treatment for ulnar neuropathy at the elbow (UNE). Researchers want to see which surgery is more helpful for people with ulnar neuropathy. This research will determine if one surgery is better than the other to alleviate symptoms.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/11/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Neuropathy Ulnar
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