New York is currently home to 4503 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Transformative Research in Diabetic Nephropathy
Recruiting
This is a prospective, observational, cohort study of patients with a clinical diagnosis of diabetes who are undergoing clinically indicated kidney biopsy. The intent is to collect, process, and study kidney tissue and to harvest blood, urine and genetic materials to elucidate molecular pathways and link them to biomarkers that characterize those patients have a rapid decline in kidney function (\> 5 mL/min/1.73m2/year) from those with lesser degrees of kidney function change over the period of... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
07/21/2025
Locations: Albert Einstein College of Medicine, Bronx, New York
Conditions: Diabetic Nephropathies, Diabetic Glomerulosclerosis
A Multinational Study Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN1)
Recruiting
This study is designed to evaluate safety and anti-tumor activity of DZD6008 in patients with advanced NSCLC with EGFR mutations.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/20/2025
Locations: Herbert Irving Comprehensive Cancer Center, New York, New York
Conditions: Non Small Cell Lung Cancer
Determining the Validity of ThinkSono Guidance for Ultrasound Image Acquisition and Remote Detection
Recruiting
The purpose of this study is to confirm the safety and efficacy of the ThinkSono Guidance System, a software data collection and communication tool designed to collect ultrasound data to help detect blood clots in veins. The ThinkSono system is CE Mark approved in the European Union and in clinical use in Europe. Usually, when an ultrasound is conducted to diagnose blood clots in veins, a sonographer (trained technologist who conducts ultrasounds) and/or radiologist will conduct the procedure, i... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/20/2025
Locations: NYU Langone Health, New York, New York
Conditions: Deep Vein Thrombosis, Deep Vein Thrombosis, Pulmonary Embolus
A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma
Recruiting
The primary objective is to determine the safety and efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indeterminate lesions (IL) or small choroidal melanoma (CM).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/20/2025
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Choroidal Melanoma, Indeterminate Lesions, Uveal Melanoma, Ocular Melanoma
Methamphetamine Cue-reactivity
Recruiting
In this observational cohort study, the researchers propose to first identify a psychophysiological marker of methamphetamine cue-reactivity and its incubation with abstinence from methamphetamine use (MUD) and examine group-differences between men who have sex with men (MSM) and non-MSM MUD. The primary objective is to identify psychophysiological markers of methamphetamine (MA) cue-reactivity and its abstinence incubation. The secondary objective is to examine group-differences in methampheta... Read More
Gender:
MALE
Ages:
Between 18 years and 60 years
Trial Updated:
07/18/2025
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Methamphetamine Use Disorder
Valganciclovir vs. Letermovir for CMV Prophylaxis in Heart Transplant
Recruiting
The purpose of this study is to compare the safety and efficacy of letermovir with valganciclovir for prevention of Cytomegalovirus (CMV) viremia in moderate to high risk serostatus heart transplant recipients.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
07/18/2025
Locations: NYP-Weill Cornell, New York, New York
Conditions: CMV Viremia, Heart Transplant Infection, Heart Transplant Failure and Rejection
A Clinical Trial of CAP-002 Gene Therapy in Pediatric Patients With Syntaxin-Binding Protein 1 (STXBP1) Encephalopathy
Recruiting
The goal of this clinical trial is to learn about the safety of CAP-002 gene therapy in children with Syntaxin-Binding Protein 1 (STXBP1) Encephalopathy. It will also provide information about whether CAP-002 demonstrates efficacy in treating children with STXBP1 with and without seizures. Participants will have a single infusion of CAP-002, visit the clinic regularly for 2 years for checkups and tests and have seizures recorded in a diary by their caregiver.
Gender:
ALL
Ages:
Between 18 months and 7 years
Trial Updated:
07/18/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Developmental and Epileptic Encephalopathy
Transcranial Direct Current Stimulation for Post Treatment Lyme Disease
Recruiting
The primary purpose of this pilot study is to investigate a novel approach to the treatment of cognitive symptoms that persist despite prior antibiotic treatment for Lyme disease (Post treatment Lyme Disease or PTLD). Aim 1: The primary aim of this study is to assess whether the processing speed of individuals with PTLD can be enhanced by combining transcranial direct current stimulation (tDCS) with computer based cognitive training games. To achieve this aim, over a 4-week period, all individu... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
07/18/2025
Locations: Columbia University Department of Psychiatry, New York, New York
Conditions: Post-Treatment Lyme Disease
Ending the Epidemic Interventions in the Dental Setting - UH3
Recruiting
The purpose of this study is to use information technology (IT) to support the efficient delivery of HIV prevention and care best practices in the dental care setting.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/18/2025
Locations: Columbia University Irving Medical Center / NewYork-Presbyterian Hospital, New York, New York
Conditions: HIV-1-infection
A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma
Recruiting
Study J2N-MC-JZ01 (JZ01) is an individual-study appendix (ISA) under master protocol J2N-MC-JZNY, and represents participants from the completed originator study, clinical study LOXO-BTK-18001/J2N-OX-JZNA. Participants in the originator study will have the opportunity to continue their assigned study intervention or continue their follow-up visits by transitioning to this study. This study will evaluate the long-term safety and efficacy of pirtobrutinib.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/18/2025
Locations: Cayuga Cancer Center, Ithaca, New York
Conditions: Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma
Mirikizumab in the Treatment of Chronic Inflammatory Conditions of the Pouch
Recruiting
The goal of this clinical trial is to learn if mirikizumab works to treat pouch disorders in adults. The main questions it aims to answer are: Does mirikizumab reduce symptoms of pouch disorders Participants will: Take mirikizumab every 4 weeks for one year Visit the clinic once every month for two months and at the end of the study Keep a diary of their symptoms
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
07/18/2025
Locations: NYU Langone Health, New York, New York
Conditions: Pouchitis, Pouches, Ileoanal, Pouch, Ileal
Innovative Automated Insulin Delivery System for Type 2 Diabetes
Recruiting
The goal of this clinical trial is to learn if the twiist insulin delivery system works to treat adults with insulin-treated type 2 diabetes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/18/2025
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Type 2 Diabetes, Insulin Treated Type 2 Diabetes Mellitus