New York is currently home to 4503 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Clinical Validation Study of the Eximis CS (Contained Segmentation) System
Recruiting
The purpose of this study is to evaluate device safety and effectiveness of the Eximis CS System.
Gender:
FEMALE
Ages:
Between 21 years and 49 years
Trial Updated:
07/08/2025
Locations: Maimonides Medical Center, Brooklyn, New York
Conditions: Laparoscopic Gynecological Surgical Procedures
DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Recruiting
This is a prospective, non-interventional, multicenter, registry of patients with pulmonary hypertension associated with interstitial lung disease (PH-ILD).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/08/2025
Locations: Northwell Health, New Hyde Park, New York
Conditions: Pulmonary Hypertension Due to Lung Diseases and Hypoxia, Pulmonary Hypertension, Interstitial Lung Disease
A Study of Pitolisant in Patients With Prader-Willi Syndrome
Recruiting
This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, global clinical study to assess the efficacy and safety of pitolisant in patients living with Prader-Willi syndrome. The primary objective of this study is to evaluate the efficacy of pitolisant in treating excessive daytime sleepiness (EDS) in patients ≥6 years of age with Prader-Willi syndrome. Secondary objectives include assessing the impact of pitolisant on: Irritable and disruptive behaviors Hyperphagia Other... Read More
Gender:
ALL
Ages:
6 years and above
Trial Updated:
07/08/2025
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Prader-Willi Syndrome
A Study of Changes in Thinking Related to Aging and Cancer in Breast Cancer Survivors (TRAC)
Recruiting
The purpose of this study is to look at how differences in cognitive (mental) function develop over time in breast cancer survivors compared to volunteers without a history of cancer (healthy volunteers). Both cancer survivors and healthy volunteers (who are the same age as the cancer survivors) will participate in this study so the researchers can compare the results of neurocognitive testing (which looks at memory, attention, and information processing) on each group of participants.
Gender:
FEMALE
Ages:
Between 60 years and 80 years
Trial Updated:
07/08/2025
Locations: Memorial Sloan Kettering Suffolk - Commack (All Protocol Activities), Commack, New York
Conditions: Breast Cancer Survivors
Rifaximin for the Secondary Prevention of Recurrent Pouchitis
Recruiting
Although many people will develop recurrent pouchitis (inflammation of the ileal pouch-anal anastomosis or J-pouch after colectomy for ulcerative colitis) after an initial episode of pouchitis, there are currently no effective treatments to prevent recurrent pouchitis. The goal of this study is to evaluate the potential for rifaximin, an antibiotic, to prevent recurrent pouchitis after treatment for an initial episode of pouchitis. In this study, all patients will be given daily rifaximin for on... Read More
Gender:
ALL
Ages:
Between 18 years and 74 years
Trial Updated:
07/08/2025
Locations: NYU IBD Center, New York, New York
Conditions: Pouchitis
Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial
Recruiting
This is a prospective, multi-center, two-arm, randomized trial to quantify the performance of the EchoMark®/EchoSure® System for AVF diagnostic ultrasound when used under a protocol of biweekly use for assessing fistula maturation and reducing time to Clinical Maturation.
Gender:
ALL
Ages:
Between 18 years and 84 years
Trial Updated:
07/08/2025
Locations: Northwell Health, New Hyde Park, New York
Conditions: Diabetes, End Stage Renal Disease
A Postpartum Adaptation Study of the Connecting and Reflecting Experience Parenting Program
Recruiting
Experiencing postpartum mood and/or anxiety disorders (like postpartum depression; PMADs) can make parenting challenging, but group therapy may help both these parents and their babies. This study will test whether postpartum parents with PMADs find a 12-session parenting group therapy to be likable, doable, and helpful for mental health, parenting stress, and relationship with their infant. The therapy that is being tested is called the Connecting and Reflecting Experience (CARE) parenting prog... Read More
Gender:
FEMALE
Ages:
Between 18 years and 70 years
Trial Updated:
07/08/2025
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Postpartum Depression, Postpartum Anxiety, Parenting Stress, Parent Child Relationships
Autoimmune and Autoinflammatory Genetics Study
Recruiting
This is an exploratory natural history protocol that will enroll patients with known genetic diseases, such as VEXAS syndrome, or as yet undiagnosed disorders of inflammation with the goal of improving our understanding of disease processes. Blood, saliva, hair, nail, or buccal samples may be collected for genetic analysis, blood samples will be obtained for immunologic and other functional studies, and a small number of subjects may undergo skin biopsy.
Gender:
ALL
Ages:
1 month and above
Trial Updated:
07/08/2025
Locations: NYC H+H/Bellevue, New York, New York
Conditions: VEXAS Syndome, Autoinflammatory Disease, Autoimmune Disease, Rheumatic Disease
Persuasive Health Communication Intervention for HIV/HCV
Recruiting
A major impediment to emergency department (ED)-based HIV/HCV screening success is that often ED patients at risk for, or later diagnosed with, HIV and HCV decline testing. In this R01 project, the research team will assess how well a promising, easy-to-use, one-time, minimal-training-needed, very brief persuasive health communication intervention (PHCI) increases acceptance of testing among adult ED patients who either currently, formerly or never injected drugs and initially declined HIV/HCV s... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/08/2025
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Human Immunodeficiency Virus (HIV), Hepatitis C (HCV)
A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants With Hearing Loss Due to Otoferlin Mutations
Recruiting
Regeneron is conducting a study of an investigational new drug called DB-OTO. DB-OTO is a gene therapy that is being developed to treat children who have hearing loss due to changes in the otoferlin gene. The purpose of this study is to: * Learn about the safety of DB-OTO * Determine how well DB-OTO is tolerated (does not cause ongoing discomfort) * Evaluate the efficacy of DB-OTO (how well DB-OTO works)
Gender:
ALL
Ages:
17 years and below
Trial Updated:
07/08/2025
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)
A Study of Tucatinib and Trastuzumab in People With Rectal Cancer
Recruiting
The study researchers believe that a combination of the drugs trastuzumab and tucatinib, given with standard chemotherapy (capecitabine and oxaliplatin/FOLFOX), may help participants with rectal cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/08/2025
Locations: Memorial Sloan Kettering Cancer Center at Suffolk - Commack (Limited Protocol Activities), Commack, New York
Conditions: Adenocarcinoma of the Rectum, Locally Advanced Rectal Adenocarcinoma, Rectal Adenocarcinoma, HER2 Positive Rectal Adenocarcinoma, Rectal Cancer
Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical Trial
Recruiting
Two-hundred and eighty individuals with schizophrenia who have a recent history of violent acts will be randomized in this 2-arm, parallel-group, 24-week, open-label, 7-site clinical trial to examine the effects of treatment with clozapine vs antipsychotic treatment as usual (TAU) for reducing the risk of violent acts in real-world settings
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
07/08/2025
Locations: NYU Langone Medical Center, New York, New York
Conditions: Schizophrenia, Schizoaffective Disorder