New York is currently home to 4502 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Propranolol and Pembrolizumab for Tumor Re-sensitization and Treatment of Patients With Checkpoint Inhibitor Refractory Metastatic or Unresectable Triple Negative Breast Cancer
Recruiting
This phase II trial tests how well propranolol and pembrolizumab work to cause tumor re-sensitization and therefore treatment in patients with triple negative breast cancer that has not responded to previous checkpoint inhibitor therapy (refractory), cannot be removed by surgery (unresectable) or has spread from where it first started (primary site) to other places in the body (metastatic). Propranolol is a drug that is classified as a beta-blocker. Beta-blockers affect the heart and circulation... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/24/2025
Locations: Roswell Park Cancer Institute, Buffalo, New York
Conditions: Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Triple-Negative Breast Carcinoma, Refractory Triple-Negative Breast Carcinoma, Unresectable Triple-Negative Breast Carcinoma
Chronic Pain in Rheumatoid Arthritis
Recruiting
The objective is to identify modifiable clinical factors and neurobiological pathways that lead to the development of chronic pain in patients with early rheumatoid arthritis. Participants will undergo quantitative sensory testing, a type of testing that involves assessing response to well-defined, quantifiable painful stimuli, at 0, 3, and 12 months. A subset of participants will also undergo magnetic resonance imaging at 0 and 12 months to assess neuroimaging markers that have previously been... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/24/2025
Locations: Hospital for Special Surgery, New York, New York
Conditions: Arthritis, Rheumatoid, Pain
Single-Fraction SBRT Versus Standard Palliative Radiation Therapy in Treating Patients With Metastatic Cancer
Recruiting
This phase II trial studies how well single-fraction stereotactic body radiation therapy (SBRT) works when compared to standard radiation therapy in treating patients with cancer that has spread to other places in the body (metastatic). Stereotactic body radiation therapy uses special equipment to position a patient and deliver radiation to tumors with high precision. This method can kill tumor cells with fewer doses over a shorter period and cause less damage to normal tissue.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/24/2025
Locations: Roswell Park Cancer Institute, Buffalo, New York
Conditions: Metastatic Malignant Neoplasm
Effects of Contralateral Strength Training on Postoperative Strength Deficits in the Immobilized Lower Extremity
Recruiting
This is a prospective, randomized controlled trial that will enroll patients undergoing unilateral meniscal root repair or meniscus transplant. The objective of this study is to determine if immediate postoperative strength training of the contralateral (non-surgical) lower extremity reduces postoperative loss of strength in an immobilized lower extremity. After the completion of surgery, patients will be randomized to either the experimental treatment (Group 1) or control group (Group II)for p... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
04/24/2025
Locations: New York University School of Medicine, New York, New York
Conditions: Meniscus; Detachment, Current Injury
Efficacy and Safety of Topical Clascoterone (WINLEVI) Cream 1% in Patients With Facial Acneiform Rosacea: A Phase 2 Clinical Trial
Recruiting
To demonstrate the efficacy of Clascoterone cream 1% in reducing the size of sebaceous glands in study participants with acneiform rosacea.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: New York Harbor VA Brooklyn Campus, Brooklyn, New York
Conditions: Papular-pustular Rosacea, Papulopustular Rosacea (PPR), Papulopustular Rosacea
Long-term Safety of Nipple Sparing Mastectomy in Women With GPV in Breast Cancer
Recruiting
Patients with a germline pathogenic variant (GPV) in high-penetrance breast cancer susceptibility genes who are considering risk reducing mastectomy (RRM) often strongly desire to keep their nipple areola complex but inquire as to whether it is safe to do so. Relative to traditional or skin sparing mastectomy (SSM) techniques, nipple sparing mastectomy (NSM) is associated with improved psychosocial and sexual well-being and is significantly better for body image and reducing feelings of disfigur... Read More
Gender:
FEMALE
Ages:
Between 18 years and 90 years
Trial Updated:
04/23/2025
Locations: Memorial Sloan Kettering Cancer Center (MSKCC), New York City, New York
Conditions: Breast Cancer Surgery
A Clinical Study to Evaluate the Safety and Efficacy of the FloStent in Men With Benign Prostatic Hyperplasia Symptoms
Recruiting
The goal of this study is to determine the safety and effectiveness of the FloStent, a medical device used to treat men with symptoms of Benign Prostatic Hyperplasia, compared to sham (procedure without deployment of the FloStent). All participants will undergo a flexible cystoscopy and those randomized to the treatment arm will receive the FloStent, while those randomized to the sham arm will not receive the FloStent.
Gender:
MALE
Ages:
45 years and above
Trial Updated:
04/23/2025
Locations: Manhattan Medical Research NYU Langone, New York City, New York
Conditions: Benign Prostatic Hyperplasia
Pilot Trial of Spiritual Care Interventions for Patients With Cancer
Recruiting
This is a pilot trial of the effects of spiritual care interventions on spiritual well-being and readiness to engage in advance care planning (ACP) among black patients with advanced cancer recruited from outpatient settings to determine the feasibility of conducting a larger trial of effects of early integration of spiritual care into outpatient oncology care on patient outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York
Conditions: Advanced Cancer
A Study Evaluating AMG 193 in Combination With Other Therapies in Participants With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous Methylthioadenosine Phosphorylase (MTAP)-Deletion
Recruiting
The study aims to determine maximum tolerated dose (MTD) or recommended combination dose of the MTA-cooperative PRMT5 inhibitor AMG 193 administered in combination with other therapies in adult participants with metastatic or locally advanced methylthioadenosine phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety profile of AMG 193 administered in combination with other therapies in adult participants with metastatic or... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
04/23/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers
A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis
Recruiting
A randomized, double-blind, placebo-controlled clinical study to evaluate the safety and efficacy of 2 doses of inhaled pirfenidone (AP01) versus placebo on top of standard of care in participants with PPF over 52 weeks.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Progressive Pulmonary Fibrosis
Long-Term Follow-Up Study of Unilateral Microtia Patients Implanted With AUR-201
Recruiting
Long-term follow-up of unilateral microtia patients implanted with AUR-201.
Gender:
ALL
Ages:
Between 8 years and 29 years
Trial Updated:
04/23/2025
Locations: Romo Plastic Surgery, New York, New York
Conditions: Microtia
Subcutaneous Implant Combination Product (AUR-201) in Patients With Unilateral Microtia
Recruiting
AUR-201 is indicated for the treatment of Grade II, III, or IV unilateral microtia in patients 8 to 29 years of age.
Gender:
ALL
Ages:
Between 8 years and 29 years
Trial Updated:
04/23/2025
Locations: Romo Plastic Surgery, New York, New York
Conditions: Microtia