New York is currently home to 4500 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Engage & Connect: A Psychotherapy for Postpartum Depression
Recruiting
This randomized controlled trial compares a novel psychotherapy, Engage \& Connect, with a Symptom Review and Psychoeducation intervention, tailored to reduce postpartum depression. The study includes 9-weeks interventions, delivered remotely. It will examine changes in social isolation, processing of social rewards and depression severity over 9 weeks of treatment.
Gender:
FEMALE
Ages:
All
Trial Updated:
04/23/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Postpartum Depression
Tumor Microenvironment Analysis of Prostate Cancer Metastasis
Recruiting
The purpose of this study is to collect prostate cancer tissue from males with metastatic prostate cancers in order to study the tumor microenvironment (TME), which is the area surrounding the tumor including cells, blood vessels, etc., in men with metastatic prostate cancer. The type of research performed on these tissue samples include genetic \& molecular analyses.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Recurrent Prostate Cancer
CYTO Reductive Surgery in Kidney Cancer Plus Immunotherapy and Targeted Kinase Inhibition
Recruiting
The purpose of this study is to determine if the use of immunotherapy nivolumab and the targeted therapy cabozantinib prior to removal of the kidney, will increase the number subjects who are without any visible kidney cancer in their body at some point during the course of treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Kidney Cancer, Renal Cell Carcinoma
Pembrolizumab And Stereotactic Radiosurgery (Srs) Of Selected Brain Metastases In Breast Cancer Patients
Recruiting
Patients with metastatic breast cancer with at least 2 brain metastases will receive pembrolizumab every 3 weeks. Patients will undergo stereotactic radiosurgery (SRS) to one of the brain lesions. Pembrolizumab infusion will be given on Day 4 (+/-1) after SRS treatment at the standard dose of 200mg IV over 30 minutes and repeated every 3 weeks until disease progression or unacceptable toxicity.
Gender:
FEMALE
Ages:
Between 19 years and 90 years
Trial Updated:
04/23/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Metastatic Breast Cancer, Brain Metastases
Brace Monitoring for Adolescent Idiopathic Scoliosis (AIS)
Recruiting
The overall aim of the study is to utilize a novel device and smartphone application in order to improve measurement of patient compliance with at-home bracing for scoliosis as well as create a more accurate assessment of brace fit via continuous and objective measures of tension. These ground-breaking metrics will provide analyzable data to more accurately reflect and predict actual patient compliance as well as allow for further exploration of how to increase compliance, and thus, efficacy of... Read More
Gender:
FEMALE
Ages:
Between 8 years and 17 years
Trial Updated:
04/23/2025
Locations: Morgan Stanley Children's Hospital of NY Presbyterian/Columbia University Medical Center, New York, New York
Conditions: Adolescent Idiopathic Scoliosis
Changes Associated With H. Pylori and Gastric Carcinogenesis
Recruiting
This is a research study for patients who currently have or previously had an H. pylori infection or who have gastric or esophageal cancer and who plan to undergo an endoscopy as part of their care. The purpose of this study is to find out how and why H. pylori infections can cause progression to gastric cancer and if it's possible for intervention prior to this progression.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Weill Cornell Medical College, New York, New York
Conditions: Bacterial Infection Due to Helicobacter Pylori (H. Pylori)
Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry
Recruiting
This real-world, international registry aims to evaluate the current experience with sodium-glucose cotransporter 2 inhibitors (SGLT2i) in adult congenital heart disease (ACHD) patients by investigating the prescription patterns, safety, tolerability, and potential beneficial effects on heart failure-related outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/22/2025
Locations: Mount Sinai Fuster Heart Hospital, New York City, New York
Conditions: Adult Congenital Heart Disease, Congenital Heart Disease, Systemic Right Ventricle, Transposition of the Great Arteries, Congenitally Corrected Transposition of the Great Arteries, Fontan, Single Ventricle, Tetralogy of Fallot (TOF)
Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial
Recruiting
This is a phase-III multi-center double-blind randomized controlled trial of 8,000 individuals undergoing a scheduled or prelabor cesarean delivery who are randomized to either adjunctive azithromycin prophylaxis or to placebo. Both groups also will receive standard of care preoperative antibiotics (excluding azithromycin). The primary endpoint is a maternal infection composite defined as any one of the following up to 6 weeks postpartum: endometritis, wound infection, abscess, septic thrombosis... Read More
Gender:
FEMALE
Ages:
All
Trial Updated:
04/22/2025
Locations: Columbia University, New York, New York
Conditions: Obstetrical Complications, Labor and Delivery Complication, Cesarean Delivery
Magnesium Sulfate as an Adjunctive Analgesic in Prostate Surgery
Recruiting
The purpose of this clinical trial is to determine if receiving magnesium sulfate as an adjunctive analgesic for prostate surgery is effective in reducing pain. Subjects will be randomized to receive magnesium or not receive it, as part of a standardized general anesthetic for prostate surgery. The primary objective is to demonstrate improved pain scores in patients receiving magnesium sulfate as an adjunctive analgesic during surgery. Secondary objectives include demonstrating reduced requireme... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
04/22/2025
Locations: NYU Langone Health, New York, New York
Conditions: Prostatectomy
FPI-2265 (225Ac-PSMA-I&T) for Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Recruiting
This is an open-label, randomized, multicenter study of FPI-2265 (225Ac-PSMA-I\&T). Patient population is adult participants with PSMA positive mCRPC who have had previous treatment with with 177Lu-PSMA-617 or another 177Lu-PSMA radioconjugate (RC). The purpose of the study is to determine the safety and tolerability, and recommended dose and regiment of FPI-2265.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
04/22/2025
Locations: Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York
Conditions: Metastatic Castration-resistant Prostate Cancer
A Study of LY4170156 in Participants With Selected Advanced Solid Tumors
Recruiting
The purpose of this study is to find out whether the study drug, LY4170156, is safe, tolerable and effective in participants with advanced solid tumors. The study is conducted in two parts - phase Ia (dose-escalation, dose-optimization) and phase Ib (dose-expansion). The study will last up to approximately 4 years.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/22/2025
Locations: NYU Langone Health, New York, New York
Conditions: Ovarian Neoplasms, Endometrial Neoplasms, Uterine Cervical Neoplasms, Carcinoma, Non-Small-Cell Lung, Triple Negative Breast Neoplasms, Pancreatic Neoplasm, Colorectal Neoplasms
Obstructive Sleep Apnea (OSA) and Sex-Specific Responses to N-acetylcysteine (NAC)
Recruiting
This is a randomized controlled trial (RCT) of 4 weeks of study supplement N-acetylcysteine (NAC) versus placebo in persons with significant obstructive sleep apnea (OSA) who are receiving positive airway pressure therapy (PAP), the standard of care therapy. The purpose of the study is to determine if NAC is associated with sex-specific changes in overnight oxidative stress, inflammation, as well as endothelial dysfunction in persons with OSA.
Gender:
ALL
Ages:
Between 55 years and 75 years
Trial Updated:
04/22/2025
Locations: NYU Langone Health, New York, New York
Conditions: Obstructive Sleep Apnea