New York is currently home to 4476 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Neurofeedback During Eating for Bulimia Nervosa
Recruiting
The purpose of this study is to examine the effects of noninvasive prefrontal cortex (PFC) neurofeedback during eating in women with bulimia nervosa (BN) using a wearable brain imaging device, functional near-infrared spectroscopy (fNIRS). The investigators will examine how this training may influence inhibitory control and BN symptoms.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
01/28/2025
Locations: Center for Computational Psychiatry at the Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Bulimia Nervosa
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants with Advanced Solid Tumors
Recruiting
This is an open label, multicenter, phase 1/2 study to assess the safety/tolerability and preliminary clinical activity of STAR0602 as a single agent administered intravenously in participants with advanced solid tumors that are antigen-rich.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/28/2025
Locations: Memorial Sloan-Kettering Cancer Center, New York, New York
Conditions: Advanced Solid Tumors, Genital Neoplasm, Female, Urogenital Neoplasms, Lung Neoplasm, Neoplasms by Site, Papillomavirus Infection, Epstein-Barr Virus Infections, Carcinoma, Neoplasms, Vulvar Neoplasms, Vulvar Diseases, Abdominal Neoplasm
A Regional Partnership to Improve Outcomes Through Fatherhood Engagement
Recruiting
Montefiore will engage fathers in families at risk of substance misuse in the Bronx and neighboring communities. Families will be referred from Bronx and neighboring community-based child welfare systems, substance use disorder (SUD) treatment providers, and medical providers if identified at risk of substance use concerns and will be randomly assigned to receive services as usual as part of the comparison group, or to receive enhanced services as part of the program group. Enhanced services in... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
01/28/2025
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Substance Use, Child Abuse, Child Neglect, Fathers, Father-Child Relations
Developing a Communication Intervention for People With Memory Challenges and Their Care Partners
Recruiting
The proposed research is consistent with broader public health goals focused on improving communication regarding end-of-life care and the Centers for Medicare and Medicaid Services' (CMS) call for increased patient engagement in advance care planning (ACP) as part of standard care. The proposed study will address this public health issue by developing a communication-based intervention designed to improve Alzheimer's Disease and Related Dementias (ADRD) patients' and care partners' engagement i... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/28/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Alzheimer Disease, Dementia
Understanding Poor Vaccine Responses to Hepatitis B Vaccination
Recruiting
Vaccines have prevented countless infections but poor vaccine responses remain a major challenge in many scenarios. Hepatitis B vaccine nonresponses are common but immunologically not well-understood. This study aims to study the immunology of hepatitis B vaccine responses by comparing traditional HBV vaccine, which is associated with nonresponses in some patients, to CpG-adjuvanted HBV vaccine, which is associated with far fewer rates of nonresponses. This research will build upon prior studie... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/28/2025
Locations: NYU Langone Health, New York, New York
Conditions: Vaccine Reaction
Cabozantinib in Patients With Metastatic Castrate Resistant Prostate Cancer (mCRPC)
Recruiting
The purpose of this study is to determine what effects (good and bad) cabozantinib has in treatment of patients with metastatic castrate resistant prostate cancer (mCRPC). The hypothesis for this trial is that cabozantinib has anti-tumor activity in a molecularly-selected group of patients with CRPC or patients with liver metastases.
Gender:
MALE
Ages:
Between 18 years and 99 years
Trial Updated:
01/28/2025
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Prostate Cancer
A Study of DF6002 Alone and in Combination With Nivolumab
Recruiting
The purpose of this study is to evaluate the safety, tolerability, drug-levels, drug-effects and preliminary anti-tumor activity of DF6002 alone and in combination with Nivolumab in participants with advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/28/2025
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Solid Tumors
Spacer Graft Study
Recruiting
To determine which of three types of spacer grafts (hard palate vs autologous ear cartilage vs Enduragen) are the most effective in lower eyelid retraction repair outcomes as measured by MRD2 (margin to reflex distance 2)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/28/2025
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Eyelid Diseases, Eyelid Droop
Longitudinal Evaluation of Microbial and Host Signatures During Immunotherapy for Lung Cancer
Recruiting
This study will prospectively collect airway, stool, and blood samples on 80 subjects with lung cancer undergoing immunotherapy. Investigators will evaluate airway/stool microbial signatures associated with local (lower airway) and systemic (blood) immune tone.They will then study whether microbiota and/or host signatures predict subjects' response by longitudinal assessment of the progression free survival. They will also repeat sampling after 8 weeks of immunotherapy to expand our mechanistic... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
01/28/2025
Locations: NYU Langone Health, New York, New York
Conditions: Lung Cancer
Modern Immunotherapy in BCG-Unresponsive, BCG-Relapsing and High Risk BCG-Naive Non-Muscle Invasive Urothelial Carcinoma of the Bladder
Recruiting
Upon successful screening and registration, enrollment to durvalumab monotherapy (cohort 1) will begin. If DLT criteria outlined in the protocol are exceeded with durvalumab monotherapy (cohort 1), the study will close. Provided the safety of durvalumab monotherapy is established, enrollment to combination regimen cohorts will proceed. Cohorts will simultaneously enroll in parallel to each other with patients assigned to cohorts based on patient slot availability and study site choice of radiati... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/28/2025
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Urothelial Carcinoma, Bladder Cancer
Modulating Movement Intention Via Cortical Stimulation
Recruiting
The purpose of this protocol is to learn about movement intention and volition. To improve such knowledge, investigators will conduct sub-studies using multiple non-invasive methodologies. These results could provide preliminary data for subsequent studies evaluating local and global efficacy of plasticity-inducing treatments for PMD symptoms.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/28/2025
Locations: New York University School of Medicine, New York, New York
Conditions: Seizures, Seizure Disorder, Psychogenic Movement Disorder
Prospective Research Assessment in Multiple Myeloma: An Observational Evaluation (PREAMBLE)
Recruiting
The purpose of this study is to assess the clinical effectiveness of all approved multiple myeloma (MM) therapies in the newly-diagnosed (NDMM) and the relapsed/refractory MM (RRMM) settings in real-world clinical practice.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/28/2025
Locations: Local Institution - 0049, Stony Brook, New York
Conditions: Multiple Myeloma