New York is currently home to 4507 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging
Recruiting
CAPTIVA-MRI is an observational multimodal MR imaging study that is ancillary to the CAPTIVA trial \[a 3-arm, double-blind Phase III trial conducted at approximately 115 StrokeNet sites randomizing patients with stroke attributed to 70-99% intracranial atherosclerotic stenosis (ICAS) to aspirin plus ticagrelor, clopidogrel, or rivaroxaban.\] The primary goal of this ancillary study is to determine if MRI biomarkers can potentially identify ICAS patients who fail best medical management. The CAPT... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/17/2025
Locations: Buffalo General Medical Center, Buffalo, New York
Conditions: Stroke, Intracranial Atherosclerotic Stenosis (ICAS)
Low-Intensity Mechanical Stimulation for Hematologic Malignancy Patients
Recruiting
This clinical trial tests the effect of low-intensity mechanical stimulation (LIMS) vibration therapy in patients with hematologic malignancies. Patients with hematologic malignancies often undergo a blood and/or bone marrow transplant (hematopoietic cell transplantation \[HCT\]) or cellular therapy. The LIMS board delivers vibrations through the bones that may stimulate bone growth and may also increase muscle activity and strength and may also increase T-cell activation in patients planning to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/17/2025
Locations: Roswell Park Comprehensive Cancer Center, Buffalo, New York
Conditions: Hematopoietic and Lymphoid System Neoplasm
Transcranial Direct Current Stimulation for Post-stroke Fatigue
Recruiting
The investigators hypothesize that delivery of anodal tDCS to the left frontal head region will reduce fatigue severity following stroke.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/17/2025
Locations: Weill Cornell Medicine, 525 E. 68th St, Baker Pavilion, F-2106, New York, New York
Conditions: Fatigue, Stroke Rehabilitaion
E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder
Recruiting
The purpose of this an open-label, randomized controlled trial study is to compare the effectiveness of electronic cigarettes (e-cigarettes/e-cigs) versus telehealth motivational counseling with combination nicotine replacement therapy (NRT) + telehealth counseling on combustible cigarettes smoking reduction among persons with opioid use disorder (OUD) in methadone and buprenorphine treatment programs (opioid use disorder treatment programs (OUDTP)). OUDTP patients are a population with exceptio... Read More
Gender:
ALL
Ages:
Between 21 years and 75 years
Trial Updated:
03/17/2025
Locations: Albert Einstein College of Medicine, Bronx, New York
Conditions: Opioid Use Disorder, Cigarette Smoking
Effect of Moderate Renal Impairment and Race/Ethnicity on Treosulfan Pharmacokinetics
Recruiting
This study aim is to assess, if treosulfan pharmacokinetics are influenced by declined renal function and by race/ethnicity of patients. The study also aims to determine an appropriate safe dose of treosulfan, when patient's renal function is impaired. The participants of this study are undergoing allogenic hematopoietic stem cell transplantation for treatment of acute myeloid leukemia or myelodysplastic syndrome.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/17/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Acute Myeloid Leukaemia (AML), Myelodysplastic Syndrome (MDS), Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)
Metabolic Mechanisms Induced by Enteral DHA and ARA Supplementation in Preterm Infants
Recruiting
A comprehensive analysis of the impact of exogenous enteral DHA and ARA supplementation on lipid metabolism including the production of downstream derived mediators and how this impacts important biological pathways such as metabolism, inflammation, and organogenic factors.
Gender:
ALL
Ages:
36 weeks and below
Trial Updated:
03/17/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Premature
A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or Refractory Multiple Myeloma
Recruiting
The purpose of this study is to assess the safety, tolerability and preliminary effectiveness of CC-92480 (BMS-986348) in novel therapeutic combinations for the treatment of Relapsed or Refractory Multiple Myeloma (RRMM).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/17/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Multiple Myeloma
Imaging of Lymphatic Vessels in People with Rheumatoid Arthritis (RA)
Recruiting
Lymphatic transport was previously examined by these investigators using Near InfraRed Indocyanine Green fluorescence imaging (NIR-ICG) of the upper extremities. They established reliable and reproducible methodologies in RA patients. The purpose of this phase 2 pilot is to study RA disease progression and effectiveness as well as the mechanism of action of clinical interventions using established NIR-ICG methodologies in previous studies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/17/2025
Locations: University of Rochester, Rochester, New York
Conditions: Rheumatoid Arthritis
Accelerated TMS for Depression and OCD
Recruiting
Repetitive transcranial magnetic stimulation (rTMS) is a FDA-approved treatment for depression and Obsessive Compulsive Disorder (OCD). The goal of the study is to learn how to optimize the treatment to improve symptoms of depression and OCD. This research project will test a new accelerated 5-day accelerated rTMS protocol for treating symptoms of depression and OCD. A second goal of this study is to identify biomarkers of depression and OCD in the brain using functional magnetic resonance imag... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
03/17/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Depression, OCD
Assessment of N-Acetylcysteine as Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Recruiting
Chronic fatigue syndrome/myalgic encephalomyelitis (ME/CFS) is an unexplained multisymptom/multisystem disorder for which there are currently no validated treatments. The present exploratory clinical trial aims to advance our understand of the mechanisms of in situ GSH synthesis control through assessment of the response of brain GSH and plasma markers of oxidative stress to different doses of NAC in comparison to placebo, as a potential treatment for ME/CFS that would provide neuroprotection ag... Read More
Gender:
ALL
Ages:
Between 21 years and 60 years
Trial Updated:
03/17/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
Tissue Analysis After Tumor Ablation for Liver Metastases Leading to Immediate Retreatment
Recruiting
This study will see whether collecting and analyzing needle biopsy samples from cancer liver metastases after a tumor ablation procedure will be able to identify cancer cells that are still alive. The results of these biopsies could help determine the next treatment for your cancer, but the biopsies could cause side effects.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/17/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Liver Metastases
Biomarker-guided rTMS for Treatment Resistant Depression
Recruiting
Repetitive transcranial magnetic stimulation (rTMS) is a treatment for depression. The investigators are continuing to learn how to optimize outcomes from rTMS treatment. The purpose of this research project is to use brain network connectivity patterns as measured by resting state functional magnetic resonance imaging (fMRI) to confirm a way to optimize the use of rTMS to treat depression. In addition, the study aims to gain a better understanding of how rTMS influences brain networks.
Gender:
ALL
Ages:
Between 22 years and 65 years
Trial Updated:
03/17/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Treatment Resistant Depression, Major Depressive Disorder