New York is currently home to 4479 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Social Determinants of Health, Medication Use, and Quality of Life in Inflammatory Bowel Disease
Recruiting
Optimizing health related-quality of life (HRQoL) for patients with inflammatory bowel disease (IBD), who often experience a relapsing disease course, is an essential component of care. Improving IBD disease control is linked to increased health-related quality of life. Even as many effective pharmacotherapies to promote disease control are available, evidence suggests that Hispanic and Non-Hispanic Black IBD patients may not receive full benefit from these therapies compared to their Non-Hispan... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/22/2025
Locations: Montefiore Hutchinson Campus, Bronx, New York
Conditions: Inflammatory Bowel Diseases
Gene Therapy for ACM Due to a PKP2 Pathogenic Variant
Recruiting
This is a Phase 1/2, first-in-human, open-label, intravenous, dose-escalating, multicenter trial that is designed to assess the safety and tolerability of LX2020 in adult patients with PKP2-ACM
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/22/2025
Locations: University of Rochester, Rochester, New York
Conditions: Arrhythmogenic Cardiomyopathy, PKP2-ACM, PKP2-ARVC
AI-Assisted Treatment for Residual Speech Sound Disorders
Recruiting
The goal of this randomized-controlled trial is to determine how artificial intelligence-assisted home practice may enhance speech learning of the "r" sound in school-age children with residual speech sound disorders. All child participants will receive 1 speech lesson per week, via telepractice, for 5 weeks with a human speech-language clinician. Some participants will receive 3 speech sessions per week with an Artificial Intelligence (AI)-clinician during the same 5 weeks as the human clinicia... Read More
Gender:
ALL
Ages:
Between 9 years and 17 years
Trial Updated:
01/22/2025
Locations: Syracuse University, Syracuse, New York
Conditions: Speech Sound Disorder
Intensive Speech Motor Chaining Treatment for Residual Speech Sound Disorders
Recruiting
The goal of this randomized-controlled trial is to compare distributed treatment schedules and intensive treatment schedules in 84 school-age children with residual speech sound disorders. The main question it aims to answer is: * How does intensive and distributed treatment affect speech sound learning in residual speech sound disorder? Some participants will be treated with a traditional Distributed schedule of 2 sessions per weeks for 8 weeks (16 hours total), whereas others will be treated... Read More
Gender:
ALL
Ages:
Between 9 years and 17 years
Trial Updated:
01/22/2025
Locations: Syracuse University, Syracuse, New York
Conditions: Speech Sound Disorder
Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - a Randomized Clinical Trial in Acute Kidney Injury
Recruiting
This randomized, controlled, pivotal study is intended to determine whether up to ten sequential 24-hour treatments with the Selective Cytopheretic Device (SCD) will improve survival in patients with Acute Kidney Injury (AKI) requiring continuous kidney replacement therapy (CKRT) when compared to CKRT alone (standard of care). This study is further intended to determine whether SCD therapy will reduce the duration of maintenance dialysis secondary to AKI. This study will enroll approximately 200... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/22/2025
Locations: Unversity of Rochester, Rochester, New York
Conditions: Acute Kidney Injury
Return to Golf After Orthopaedic Surgery
Recruiting
The GOLF study is a multicenter, prospective study with the goal to investigate golfers' return to the sport following hip, knee or shoulder arthroplasty. The prevalence of return to golf, by level of returning to golf will be assessed at 6 weeks, 3 months, 6 months, and 12 months postoperatively. Patients who are active golfers undergoing joint replacement will be identified from outpatient clinics and pre-assessment clinics and given information about the study at least two weeks prior to surg... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/22/2025
Locations: Hospital for Special Surgery, New York, New York
Conditions: Hip Osteoarthritis, Knee Osteoarthritis, Shoulder Osteoarthritis
A Study of CYP-001 in Combination with Corticosteroids in Adults with High-risk AGvHD
Recruiting
This study is a prospective randomized placebo-controlled phase 2 study to compare CYP-001 plus corticosteroids (CS) to placebo plus CS in allogeneic hematologic stem cell transplant recipients with HR-aGvHD. Severity of GvHD will be assessed at screening and throughout the study using Mount Sinai Acute GvHD International Consortium (MAGIC) guidelines. Eligible subjects will be randomized to receive either CYP-001 IV infusion on Days 0 and 4 or placebo on the same days. All subjects will receive... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/22/2025
Locations: Weill Cornell Medicine - New York Presbyterian Hospital, New York, New York
Conditions: Graft Versus Host Disease, Acute
Diabetes Care for Breast Cancer Patients
Recruiting
The goal of this study is to find a new way to make diabetes care better for patients with breast cancer and diabetes who are currently receiving cancer treatment. We will have two groups, the researchers will decide who is in which group. One group will be working with a nurse who is trained in diabetes care while the other does not. This will allow the investigators to see if having a trained nurse as part of the care team can help improve the care the patients receive.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/22/2025
Locations: NewYork-Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York
Conditions: Breast Cancer, PreDiabetes, Type 2 Diabetes
PRP in ACLR to Prevent PTOA
Recruiting
The purpose of our study is to examine the effect of platelet-rich-plasma (PRP) injection on the short-term resolution of post-injury inflammation (biomarkers) and improvement in joint function in patients with acute ACL injury. This RCT has been powered based on the questionnaire KOOS Jr. but it is considered a 'pilot study' in terms of the lab analysis proposed.
Gender:
ALL
Ages:
Between 14 years and 50 years
Trial Updated:
01/22/2025
Locations: Hospital for Special Surgery, New York, New York
Conditions: Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, PRP
Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma
Recruiting
This study is for patients with newly diagnosed glioblastoma, as well as patients who have recurring glioblastoma. Subjects will be given daily paxalisib and metformin while also maintaining a ketogenic diet. The purpose of this study is to assess the safety of Paxalisib while maintaining a ketogenic diet (a high fat, low carbohydrate diet) and Metformin (a drug approved by the Food and Drug Administration to treat type 2 diabetes), and to see what effects it has on glioblastoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/22/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Glioblastoma
Tissue Collection for Drug Screening and Bioanalysis
Recruiting
The purpose of this study is to improve upon the knowledge currently available about central nervous system (CNS) tumors. We will study the different characteristics of these tumors using tissue samples collected during surgery and post-autopsy. The aim is to create tumor cell lines and models to test how they respond to different drugs. This research will help improve treatment options and identify new targets for therapy.
Gender:
ALL
Ages:
All
Trial Updated:
01/22/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Central Nervous System Tumor
Reducing Suicide Risk in Older Veterans Using Problem Solving Therapy
Recruiting
Suicide is a national crisis, especially among older Veterans for whom evidence-based suicide prevention efforts are lacking. This proposal responds to the national priority to develop and improve interventions for suicide prevention, with a focus on at-risk older Veterans. The randomized control trial will compare VA usual care, which is suicide safety planning, with brief Problem Solving Therapy and suicide safety planning. This study uses Problem Solving Therapy because it has support from ou... Read More
Gender:
ALL
Ages:
55 years and above
Trial Updated:
01/22/2025
Locations: Syracuse VA Medical Center, Syracuse, NY, Syracuse, New York
Conditions: Suicidal Ideation, Depressive Disorder, Anxiety Disorders, Post Traumatic Stress Disorder