New York is currently home to 4471 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Diabetes Care for Breast Cancer Patients
Recruiting
The goal of this study is to find a new way to make diabetes care better for patients with breast cancer and diabetes who are currently receiving cancer treatment. We will have two groups, the researchers will decide who is in which group. One group will be working with a nurse who is trained in diabetes care while the other does not. This will allow the investigators to see if having a trained nurse as part of the care team can help improve the care the patients receive.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/22/2025
Locations: NewYork-Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York
Conditions: Breast Cancer, PreDiabetes, Type 2 Diabetes
PRP in ACLR to Prevent PTOA
Recruiting
The purpose of our study is to examine the effect of platelet-rich-plasma (PRP) injection on the short-term resolution of post-injury inflammation (biomarkers) and improvement in joint function in patients with acute ACL injury. This RCT has been powered based on the questionnaire KOOS Jr. but it is considered a 'pilot study' in terms of the lab analysis proposed.
Gender:
ALL
Ages:
Between 14 years and 50 years
Trial Updated:
01/22/2025
Locations: Hospital for Special Surgery, New York, New York
Conditions: Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, PRP
Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma
Recruiting
This study is for patients with newly diagnosed glioblastoma, as well as patients who have recurring glioblastoma. Subjects will be given daily paxalisib and metformin while also maintaining a ketogenic diet. The purpose of this study is to assess the safety of Paxalisib while maintaining a ketogenic diet (a high fat, low carbohydrate diet) and Metformin (a drug approved by the Food and Drug Administration to treat type 2 diabetes), and to see what effects it has on glioblastoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/22/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Glioblastoma
Tissue Collection for Drug Screening and Bioanalysis
Recruiting
The purpose of this study is to improve upon the knowledge currently available about central nervous system (CNS) tumors. We will study the different characteristics of these tumors using tissue samples collected during surgery and post-autopsy. The aim is to create tumor cell lines and models to test how they respond to different drugs. This research will help improve treatment options and identify new targets for therapy.
Gender:
ALL
Ages:
All
Trial Updated:
01/22/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Central Nervous System Tumor
Reducing Suicide Risk in Older Veterans Using Problem Solving Therapy
Recruiting
Suicide is a national crisis, especially among older Veterans for whom evidence-based suicide prevention efforts are lacking. This proposal responds to the national priority to develop and improve interventions for suicide prevention, with a focus on at-risk older Veterans. The randomized control trial will compare VA usual care, which is suicide safety planning, with brief Problem Solving Therapy and suicide safety planning. This study uses Problem Solving Therapy because it has support from ou... Read More
Gender:
ALL
Ages:
55 years and above
Trial Updated:
01/22/2025
Locations: Syracuse VA Medical Center, Syracuse, NY, Syracuse, New York
Conditions: Suicidal Ideation, Depressive Disorder, Anxiety Disorders, Post Traumatic Stress Disorder
A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imaging
Recruiting
This clinical trial is for men and women with high-grade gliomas. Glucose (sugar) is thought to be a contributor to tumor growth. The ketogenic diet (a high fat, low carbohydrate diet) and metformin (a drug approved by the Food and Drug Administration to treat type 2 diabetes) are both known to lower blood glucose levels. The purpose of the study is to evaluate the tolerability of a ketogenic diet in conjunction with metformin and whether maintaining and the diet with metformin will have any eff... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/22/2025
Locations: Columbia University, New York, New York
Conditions: Glioblastoma
Study of RP1 Monotherapy and RP1 in Combination With Nivolumab
Recruiting
RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects with advanced and/or refractory solid tumors, to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D), as well as to evaluate preliminary efficacy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/22/2025
Locations: New York University Clinical Cancer Center, New York, New York
Conditions: Cancer, Melanoma (Skin), Mismatch Repair Deficiency, Microsatellite Instability, Non-melanoma Skin Cancer, Cutaneous Melanoma, NSCLC
Study of the Kono-S Anastomosis Versus the Side-to-side Functional End Anastomosis
Recruiting
This study proposes a randomized prospective study comparing the Kono-S anastomosis to the standard side-to-side anastomosis.This will be a multi-center randomized prospective trial. Patients with Crohn's ileitis or Crohn's ileocolitis requiring resection will be randomized to undergo either the Kono-S anastomosis or the side-to-side functional end anastomosis.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
01/22/2025
Locations: Weill Cornell Medical College, New York, New York
Conditions: Crohn's Disease
Gamete Treatment to Correct Fertilization Failure
Recruiting
In this proposed research study, the investigators plan to assess the efficacy of gametes' (egg and sperm) treatment on fertilization as well as pre- and post-implantation embryo development.
Gender:
ALL
Ages:
Between 21 years and 89 years
Trial Updated:
01/22/2025
Locations: Center fo Reproductive Medicine, New York, New York
Conditions: Infertility
Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol
Recruiting
ENGAGE (Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol) is a Phase 3, randomized, double-blind, placebo-controlled, multicenter trial to assess the efficacy and safety of solriamfetol for the treatment of binge eating disorder (BED) in adults.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
01/21/2025
Locations: Clinical Research Site, Mount Kisco, New York
Conditions: Binge-Eating Disorder
Posterior Wall Substrate Modification Using Irreversible Electroporation for Paroxysmal Atrial Fibrillation
Recruiting
The purpose of this study is to compare the efficacy and safety between pulmonary vein isolation (PVI) alone versus PVI with left atrial (LA) posterior wall isolation (PWI) using pulsed-field ablation (PFA) in the treatment of patients with paroxysmal atrial fibrillation (PAF).
Gender:
ALL
Ages:
Between 21 years and 90 years
Trial Updated:
01/21/2025
Locations: North Shore University Hospital, Northwell Health, Manhasset, New York
Conditions: Atrial Fibrillation Paroxysmal
A Study with L19TNF in Combination with Lomustine in Patients with Glioblastoma At Progression or Recurrence
Recruiting
The trial aims to collect safety, efficacy, exposure, dose- response, pharmacokinetic and pharmacodynamic information of the combination of L19TNF and lomustine at different dose levels in patients with Glioblastoma at progression or recurrence
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/21/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Glioblastoma