New York is currently home to 4499 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
Recruiting
This is a Phase 1/2 open-label, multi-center, multi-national study with an initial dose escalation part to determine the recommended Phase II dose (RP2D) of MCLA-158 single agent in patients with mCRC. The dose escalation part has been completed and the RP2D will be further evaluated in an expansion part of the study. Cohorts of selected solid tumor indications for which there is evidence of EGFR dependency and potential sensitivity to EGFR inhibition will be evaluated including head and neck c... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/27/2025
Locations: Cayuga Medical Center, Ithaca, New York
Conditions: Advanced/Metastatic Solid Tumors, Colorectal Cancer, Gastric Cancer, Gastroesophageal-junction Cancer, NSCLC, HNSCC, Head and Neck Squamous Cell Carcinoma, Esophageal Cancer
Fecal Microbiota Transplant National Registry
Recruiting
A national data registry of patients receiving fecal microbiota transplantation (FMT) or other gut-related-microbiota products designed to prospectively assess short and long-term safety and effectiveness
Gender:
ALL
Ages:
All
Trial Updated:
01/27/2025
Locations: Concorde Medical Group, New York, New York
Conditions: Fecal Microbiota Transplantation, Clostridium Difficile Infection, Gut Microbiome
Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors
Recruiting
First, the investigators plan to use a retrospective analysis to determine the clinical landscape of neurofibromatosis (NF)1-associated malignant peripheral nerve sheath tumor (MPNST) and precursor lesions (e.g., atypical or nodular plexiform neurofibromas). A worldwide database will be established, collecting, in a standardized manner, histologic, immunohistochemical, molecular, radiographic, treatment, and related clinical data from centers worldwide with expertise in these NF1-related cancers... Read More
Gender:
ALL
Ages:
All
Trial Updated:
01/27/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Malignant Peripheral Nerve Sheath Tumors
Post-Operative Thoracolumosacral Orthosis for PJK
Recruiting
Proximal junctional kyphosis (PJK) is a common post-operative radiographic finding after surgery for adult spinal deformity (ASD) patients. Although the clinical relevance of isolated PJK is unclear, PJK can progress to symptomatic proximal junctional failures which requires a large revision surgery. Currently, post-operative bracing with a thoracolumbosacral orthosis (TLSO) is common practice after spinal deformity surgery, however the efficacy of this in preventing PJK is unknown. This multi-c... Read More
Gender:
ALL
Ages:
Between 30 years and 75 years
Trial Updated:
01/24/2025
Locations: Hospital for Special Surgery, New York City, New York
Conditions: Proximal Junctional Kyphosis, Adult Spinal Deformity Surgery, Thoracolumbosacral Orthosis
Prospective Multi-Center Trial for FemBloc Permanent Birth Control
Recruiting
Prospective, multi-center, international, unblinded, single-arm trial of subjects undergoing FemBloc followed by ultrasound confirmation test.
Gender:
FEMALE
Ages:
Between 21 years and 50 years
Trial Updated:
01/24/2025
Locations: Maimonides Medical Center, Brooklyn, New York
Conditions: Contraception
BREATHE: An Efficacy-implementation Trial Among Black Adults With Uncontrolled Asthma
Recruiting
This study is an efficacy-implementation trial to: 1. evaluate systematically the efficacy of BREATHE in 200 Black adults receiving care at urban federally qualified health centers (FQHCs) for uncontrolled asthma; and 2. identify multi-level barriers and facilitators to the widespread adoption and implementation of BREATHE in FQHCs.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2025
Locations: Sun River Health, Beacon, New York
Conditions: Asthma
EMS Providers' Health Initiative Study
Recruiting
This study aims to explore dietary factors that influence glycemic control in night shift EMS providers and to test the feasibility of a dietary intervention among these providers.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2025
Locations: University at Buffalo, Buffalo, New York
Conditions: Shift-work Disorder
De-convoluting Interactions Between Genes, the Cancer Environment, and the Immune System to Develop Therapies That Work for You
Recruiting
This is a live biobank study for breast cancer (BC) patients where samples will be collected at inflection points in the course of the disease.
Gender:
FEMALE
Ages:
Between 18 years and 90 years
Trial Updated:
01/24/2025
Locations: Brooklyn Methodist Hospital - NewYork Presbyterian, New York, New York
Conditions: Breast Cancer
Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression
Recruiting
This study seeks to evaluate the impact of intra-operative topical epidural steroid usage in patients undergoing 1-2 level lumbar laminectomy. The study will examine post-operative opioid usage, length of stay, return to work, and patient reported outcomes following these procedures.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
01/24/2025
Locations: Hospital for Special Surgery, New York, New York
Conditions: Opioid Use, Lumbar Spinal Stenosis, Pain, Postoperative, Pain, Back
Combined Immunotherapies in Metastatic ER+ Breast Cancer
Recruiting
Women with Hormone Receptor (HR)+ Human Epidermal growth factor Receptor (HER)2- metastatic breast cancer are eligible to a randomized trial. Patients receiving standard first line therapy for metastatic HR+ Breast cancer(BC) (letrozole+palbociclib) are randomly assigned to also receive Stereotactic Body Radiation Therapy(SBRT) to each metastatic lesion.
Gender:
FEMALE
Ages:
Between 18 years and 90 years
Trial Updated:
01/24/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Breast Cancer
Undifferentiated Connective Tissue Disease Registry
Recruiting
This registry has been established to gain a better understanding of the clinical and emotional presentations of patients with undifferentiated connective tissue disease.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2025
Locations: Hospital for Special Surgery, New York, New York
Conditions: Undifferentiated Connective Tissue Disease
Occlusion Balloon vs. 5FR Ureteral Catheter
Recruiting
Occlusion Balloon catheter provides the ability to occlude the exit of the kidney pelvis during percutaneous nephrolithotomy (PCNL) and potentially prevents the migration of stone fragments into the ureter. The necessity for it might be questioned during supine PCNL due to the upward oblique position of the kidney. The objective of the study is to compare the presence of ureteral stone fragments upon completion of supine PCNL with and without using an occlusion balloon catheter (OBC).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/23/2025
Locations: Mount Sinai West, New York, New York
Conditions: Kidney Stones