New York is currently home to 4503 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Mechanisms of Resistance to PSMA Radioligand Therapy
Recruiting
This is a multicenter, correlative study to existing Lutetium based prostate-specific membrane antigen (PSMA)-targeted radioligand therapy (RLT) trials and uses.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2025
Locations: Memorial Sloan Kettering, New York, New York
Conditions: Prostate Cancer
taVNS on Pupillary Response and Perceptual Learning
Recruiting
This study has two parts. The study team will evaluate transcutaneous auricular vagal nerve stimulation (taVNS) and two sham settings during a passive task while measuring pupillary response. Second, the study team will assign either taVNS, sham, or no intervention during a go/no-go task and evaluate perceptual learning over three sessions which will also include measuring the pupillary response and electroencephalogram (EEG).
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/29/2025
Locations: NYU Langone Health - Bellevue Hospital, New York, New York
Conditions: Pupillary Response
BRInging the Diabetes Prevention Program to GEriatric Populations
Recruiting
Over 24 million Americans are over 65 years and have prediabetes. Prediabetes can be addressed using a public health approach: among the 20% of participants in the Diabetes Prevention Program (DPP) who were ages 60 and over, the diet and physical activity intervention conferred a 71% risk reduction of diabetes after an average follow-up of 3 years. The population of older adults is projected to more than double from 52.5 million in 2019 to \~100 million by 2060, and if projections hold, about ha... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
01/29/2025
Locations: NYU Langone Health, New York, New York
Conditions: Pre Diabetes
Use of Artificial Intelligence for Clinical Assessment of Assisted Reproductive Techniques and IVF Outcomes
Recruiting
The use of machine learning techniques using an artificial intelligence tool is proposed to analyze clinical data to predict best possible IVF/ART outcomes. This tool has been utilized to accurately predict embryo quality here at Cornell. Utilizing this tool to assess objective clinical findings and predict outcomes of assisted reproductive techniques is sought, with the ultimate goal of an automated tool to reduce implicit physician bias. Within this goal, using this tool to objectively and acc... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
01/29/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Infertility, in Vitro Fertilization (IVF), ART
Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation
Recruiting
Prospective, controlled, multicenter clinical investigation with four trial cohorts: Randomized, Non-repairable, Severe Mitral Annular Calcification (MAC) and Severe Mitral Annular Calcification Continued Access Protocol (MAC CAP). Subjects in the Randomized cohort will be randomized in a 1:1 ratio to the trial device or to the MitraClip system. Subjects in the Non-repairable, Severe MAC, and Severe MAC CAP cohorts will receive the trial device. The objective of the Clinical Trial to Evaluate t... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2025
Locations: Albany Medical College at Albany Medical Center, Albany, New York
Conditions: Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Insufficiency, Cardiovascular Diseases, Valve Disease, Heart, Heart Valve Diseases, Functional Mitral Regurgitation, Degenerative Mitral Valve Disease
A Clinical Trial to Evaluate the Safety and Immunogenicity of CH505M5 N197D mRNA-gp160 Followed by CH505 TF mRNA-gp160 in Adults in Overall Good Health Without HIV
Recruiting
This is a multicenter, open-label, non-randomized, dose escalation, first-in-human (FIH) trial to evaluate the safety and immunogenicity of CH505M5 N197D mRNA-gp160 and CH505 TF mRNA-gp160. Both products are mRNA encapsulated in lipid nanoparticles (LNPs) (subsequently referred to as mRNA-LNPs). The primary hypotheses are: 1. the CH505M5 N197D mRNA-gp160 will expand CH235-like B cell precursors, 2. the CH505 TF mRNA-gp160 will boost CH235-like bnAb B cell precursors to acquire more functional m... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
01/28/2025
Locations: Columbia P&S (Site ID: 30329), New York, New York
Conditions: HIV Infections
Changes in Inhibition and Valuation After Eating
Recruiting
An impaired ability to exert control has been implicated in bulimia nervosa (BN), but this impairment may not represent a stable trait or be the most effective focus for treatment. This project aims to understand how predictions and value-based decisions about control may be abnormally influenced by eating in individuals with BN, thereby maintaining cycles of binge eating, purging, and restriction.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
01/28/2025
Locations: Center of Excellence in Eating and Weight Disorders at the Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Bulimia Nervosa
Psychological Assessment of Scoliosis Patients Undergoing Surgical Management
Recruiting
Working in partnership with Montefiore-Einstein's Department of Translational Psychiatry, the study team investigators have designed a prospective randomized clinical trial (2:1) study for 45 AIS patients (10-19 yrs.). This protocol includes a baseline assessment of mental health, pain, and function in AIS patients utilizing validated patient reported outcome measures. The investigators will implement and test a structured perioperative psychological intervention program, based on the Aim to Dec... Read More
Gender:
ALL
Ages:
Between 10 years and 19 years
Trial Updated:
01/28/2025
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Adolescent Idiopathic Scoliosis (AIS), Mental Health
Neurofeedback During Eating for Bulimia Nervosa
Recruiting
The purpose of this study is to examine the effects of noninvasive prefrontal cortex (PFC) neurofeedback during eating in women with bulimia nervosa (BN) using a wearable brain imaging device, functional near-infrared spectroscopy (fNIRS). The investigators will examine how this training may influence inhibitory control and BN symptoms.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
01/28/2025
Locations: Center for Computational Psychiatry at the Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Bulimia Nervosa
A Regional Partnership to Improve Outcomes Through Fatherhood Engagement
Recruiting
Montefiore will engage fathers in families at risk of substance misuse in the Bronx and neighboring communities. Families will be referred from Bronx and neighboring community-based child welfare systems, substance use disorder (SUD) treatment providers, and medical providers if identified at risk of substance use concerns and will be randomly assigned to receive services as usual as part of the comparison group, or to receive enhanced services as part of the program group. Enhanced services in... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
01/28/2025
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Substance Use, Child Abuse, Child Neglect, Fathers, Father-Child Relations
Understanding Poor Vaccine Responses to Hepatitis B Vaccination
Recruiting
Vaccines have prevented countless infections but poor vaccine responses remain a major challenge in many scenarios. Hepatitis B vaccine nonresponses are common but immunologically not well-understood. This study aims to study the immunology of hepatitis B vaccine responses by comparing traditional HBV vaccine, which is associated with nonresponses in some patients, to CpG-adjuvanted HBV vaccine, which is associated with far fewer rates of nonresponses. This research will build upon prior studie... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/28/2025
Locations: NYU Langone Health, New York, New York
Conditions: Vaccine Reaction
Cabozantinib in Patients With Metastatic Castrate Resistant Prostate Cancer (mCRPC)
Recruiting
The purpose of this study is to determine what effects (good and bad) cabozantinib has in treatment of patients with metastatic castrate resistant prostate cancer (mCRPC). The hypothesis for this trial is that cabozantinib has anti-tumor activity in a molecularly-selected group of patients with CRPC or patients with liver metastases.
Gender:
MALE
Ages:
Between 18 years and 99 years
Trial Updated:
01/28/2025
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Prostate Cancer