New York is currently home to 4494 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Health Protection and Promotion of Sign Language Interpreters Through Implementation of Total Worker Health®
Recruiting
Using mixed-methods and a clinical efficacy trial design, the overall objective of this study will employ implementation strategies to adapt and evaluate a previous integrated Total Worker Health® (TWH®) program and pilot test its efficacy on sign language interpreter well-being. The central hypothesis is that interpreters in the health protection and promotion program (intervention) will demonstrate significantly improved well-being compared to those in a general health program (control).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/16/2024
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Well-Being, Psychological
SKB264 in Combination With Pembrolizumab in Subjects With Selected Solid Tumors
Recruiting
The purpose of this study is to evaluate the efficacy and safety of combination of SKB264 and Pembrolizumab in patients with selected solid tumors including cervical cancer, urothelial cancer, ovarian cancer, prostate cancer,advanced endometrial cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/16/2024
Locations: Westchester Medical Center, Hawthorne, New York
Conditions: Solid Tumor
A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer
Recruiting
This is a randomized controlled trial to compare survival for patients who undergoe robotic assisted laparoscopy versus open hysterectomy and lymph node assessment for the treatment of early stage cervical cancer.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/16/2024
Locations: Northwell Health/South Shore University Hospital, Bay Shore, New York
Conditions: Cervical Cancer
Rare CFTR Mutation Cell Collection Protocol (RARE)
Recruiting
Over 1,900 mutations in the gene for the cystic fibrosis transmembrane conductance regulator (CFTR) protein are implicated in causing Cystic Fibrosis (CF). Potential therapies that directly target defective CFTR are being evaluated in important clinical trials, but most target the most common CFTR mutation F508del. Many patients with rare CF mutations are not able to participate in those studies. The RARE study is specifically designed for people with CF caused by rare mutations. Eligible rare m... Read More
Gender:
ALL
Ages:
12 years and above
Trial Updated:
12/16/2024
Locations: Morgan Stanley Children's Hospital of New York, New York, New York
Conditions: Cystic Fibrosis
Sudden Unexplained Death in Childhood (SUDC) Registry
Recruiting
The purpose is to increase the understanding of the characteristics, circumstances, medical histories and pathologies of children from ages 11 months through 18 years who have died suddenly and unexpectedly, and in some instances, without explanation. The SUDC Registry and Research Collaborative will analyze cases of sudden unexpected deaths in these children to understand risk factors and causes, and develop preventative measures.
Gender:
ALL
Ages:
Between 11 months and 100 years
Trial Updated:
12/16/2024
Locations: New York University School of Medicine, New York, New York
Conditions: Sudden Unexplained Death Syndrome, Sudden Unexplained Death in Childhood
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction
Recruiting
This study will demonstrate the safety and effectiveness of the Edwards Lifesciences SAPIEN 3/SAPIEN 3 Ultra RESILIA Transcatheter Heart Valve (THV) Systems in subjects with a dysfunctional right ventricular outflow tract (RVOT) conduit or previously implanted valve in the pulmonic position with a clinical indication for intervention.
Gender:
ALL
Ages:
All
Trial Updated:
12/16/2024
Locations: Columbia University Medical Center/NYPH, New York, New York
Conditions: Complex Congenital Heart Defect, Dysfunctional RVOT Conduit, Pulmonary Valve Insufficiency, Pulmonary Valve Degeneration
Hand Transplantation
Recruiting
The purpose of this study is to see if an investigational surgery that transfers tissue from a non-living donor to living individual will help restore greater function, appearance, and sensation to the hand and forearm areas of individuals who have suffered traumatic injury to the hand and forearm. This procedure is called a hand allotransplantation or "hand transplant". This study will also collect data on how patients do during and after having a hand transplant from a nonliving donor. Recov... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
12/16/2024
Locations: NYU Langone Ambulatory Care Center, New York, New York
Conditions: Amputation
Auditory Brainstem Implant (ABI) in Children With No Cochleae or Auditory Nerves
Recruiting
This study is a feasibility study of the Nucleus 24 ABI in children without NF2. It will be conducted as a repeated-measures, single subject experiment in order to accommodate the known variability in cochlear implant clinical results. Data obtained in the course of this study will be compared with the existing published outcome data from children with normal hearing and with cochlear implants (CIs). These comparisons may provide additional useful information about the progress of ABI subjects'... Read More
Gender:
ALL
Ages:
Between 18 months and 21 years
Trial Updated:
12/16/2024
Locations: NYU Cochlear Implant Center, New York, New York
Conditions: Hearing Loss, Bilateral (Causes Other Than Tumors)
Brain [18F]-FES PET/CT in Patients With Estrogen-Receptor Positive Breast Cancer
Recruiting
The goal of this interventional study is to optimize the protocol of FES PET/CT in Estrogen Receptor positive Breast cancer patients with Brain metastases. Patients will undergo MRI of the brain and FDG PET/CT brain as part of standard of care for radiation treatment planning. An additional 18F-FES PET/CT brain scan will be completed before this standard of care radiation treatment. Patients will be followed prospectively with clinical and MRI assessments per standard-of-care for a total of 12 m... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/13/2024
Locations: New York-Presbyterian/Weill Cornell Medical Center, New York, New York
Conditions: Breast Cancer, Brain Metastases
IMPOWR-ME Project 1: Trial of Yoga and Physical Therapy Onsite at Opioid Treatment Programs
Recruiting
This is a pragmatic, open label, randomized controlled trial with 1:1:1 allocation to 12 weeks of: (1) onsite yoga at opioid treatment programs (OTPs), (2) onsite physical therapy (PT) at OTPs, or (3) treatment as usual (TAU). Participants will be 345 individuals with chronic back pain receiving treatment for opioid use disorder (OUD) in community-based OTPs. Through research visits at screening, baseline, and months 1, 2, 3, 6, and 9, the investigators will evaluate pain and opioid use outcomes... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
12/13/2024
Locations: Montefiore DoSA Wellness Centers, Bronx, New York
Conditions: Substance Use Disorders, Chronic Pain, Opioid Use Disorder, Back Pain Lower Back Chronic
VIBRANT: VIB4920 for Active Lupus Nephritis
Recruiting
This is a multi-center double-blind placebo controlled clinical trial evaluating the efficacy of VIB4920 combined with mycophenolate mofetil (MMF) and prednisone in achieving a renal response in participants with active lupus nephritis (LN).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/13/2024
Locations: Feinstein Institute for Medical Research: Center for Autoimmune and Musculoskeletal Diseases, Manhasset, New York
Conditions: Lupus Nephritis
Randomized Trial of ACT and a Care Management App in Primary Care-based Buprenorphine Treatment
Recruiting
The proposed IMPOWR Research Center at Montefiore-Einstein (IMPOWR-ME) will create a multidisciplinary and synergistic program of research to test multimodal treatments that address both chronic pain and opioid use disorder. IMPOWR-ME will generate critical knowledge about the effectiveness, implementation, and cost effectiveness of providing Acceptance and Commitment Therapy and/or a care management smartphone app for individuals in primary care-based buprenorphine treatment. Patients with live... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/13/2024
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Opioid-use Disorder, Chronic Pain