New York is currently home to 4476 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Kidney Cancer DNA Registry
Recruiting
This registry will help us develop better methods of: * Preventing these cancers * Diagnosing these cancers * Treating these cancers
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/11/2024
Locations: Memorial Sloan Kettering Commack (Consent and Follow-up), Commack, New York
Conditions: Renal Cancer
ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials
Recruiting
This study will follow men with metastatic castration resistant prostate cancer throughout their standard of care treatment for their disease to determine if the presence of different genes or proteins can predict which patients respond to the cancer treatment they receive. As tumors grow and begin to spread, they may release cells into patients' bloodstream. These cells are called "circulating tumor cells", or CTCs. CTCs can be used to look for differences in "biomarkers" (genes or proteins tha... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
10/10/2024
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Prostate Cancer, Prostate Adenocarcinoma, Prostate Cancer Metastatic, Castration-resistant Prostate Cancer
E-cigarettes for Harm Reduction Among Smokers With Serious Mental Illness
Recruiting
In this open-label, randomized controlled trial study, participants who smoke combustible cigarettes (CC) and are diagnosed with Serious Mental Illness (SMI) will be randomized in two arms to receive harm-reduction counseling and Ecological Momentary Intervention text messaging (EMI) along with either e-cigarettes (EC) or nicotine replacement therapy (NRT) such as patch and lozenges to compare the efficacy in CC smoking reduction.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
10/10/2024
Locations: NYU Langone Health, New York, New York
Conditions: Cigarette Smoking
Lay-Delivered Behavioral Activation in Senior Centers
Recruiting
In response to large numbers of senior center clients who suffer untreated depression and the dearth of geriatric mental health providers, the investigators have simplified Behavioral Activation to be delivered by lay volunteers ("Do More, Feel Better"; DMFB). The focus of Behavioral Activation is to guide clients to reengage in daily pleasant and rewarding activities, and reduce depressive symptoms. If the investigators can show that the lay delivery model has positive impact in comparison to M... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
10/10/2024
Locations: Diana Jones Senior Center, Brooklyn, New York
Conditions: Depression
Ribociclib and Bicalutamide in AR+ TNBC
Recruiting
This is an open label, multi-institutional, single arm phase II trial of ribociclib in combination with bicalutamide in advanced AR+ triple-negative breast cancer. No randomization or blinding is involved.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/10/2024
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Triple Negative Breast Cancer
Impella RP Flex with Smart Assist
Recruiting
To capture observational data of the Abiomed Impella RP Flex in a real-world setting.
Gender:
ALL
Ages:
All
Trial Updated:
10/09/2024
Locations: Montefiore Medical Center - Moses, Bronx, New York
Conditions: Right Ventricular (RV) Dysfunction
Intrathecal Dexmedetomidine Vs Epinephrine
Recruiting
Several studies have shown that adding dexmedetomidine or epinephrine to single-dose spinal analgesia preparations improves the length and/or speed of onset of the sensory block and post-operative pain management without increased negative side effects. To date, however, no study has compared adjunctive intrathecal dexmedetomidine to adjunctive intrathecal epinephrine in single-dose spinal analgesia. The purpose of this study is to determine if adjunctive intrathecal dexmedetomidine is non-infer... Read More
Gender:
FEMALE
Ages:
Between 18 years and 55 years
Trial Updated:
10/09/2024
Locations: Mount Sinai Hospital, New York, New York
Conditions: Cesarean Section, Anesthesia, Spinal
A Digitally Assisted Risk Reduction Platform for Youth At High Risk for Suicide
Recruiting
Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death among youth. Digital tools, especially personal smartphones, are promising avenues to address these issues and can be used to provide a unique understanding of risk factors, including psychological distress, anhedonia and behavioral withdrawal, and sleep disturbance among high-risk individuals. This project aims to enhance the effectiveness of the delivery of preventative health care to yo... Read More
Gender:
ALL
Ages:
Between 13 years and 18 years
Trial Updated:
10/09/2024
Locations: Columbia University, New York, New York
Conditions: Suicide, Mental Health Disorder, Anhedonia
How Hormones and Exposure and Response Prevention (EX/RP) Affect the Brain of People With OCD
Recruiting
Studies show that hormones affect the brain's fear extinction network, which is relevant for therapy involving exposure and response prevention (EX/RP), a first-line treatment for obsessive compulsive disorder (OCD). This study will examine the effect of delivering EX/RP to women during different phases in their menstrual cycle to determine the effects of hormones on the fear extinction network and on their OCD symptoms.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
10/09/2024
Locations: New York State Psychiatric Institute, New York, New York
Conditions: OCD
Mono vs. Dual Therapy for Pediatric Pulmonary Arterial Hypertension
Recruiting
The investigators' central hypothesis is that early combination therapy with two PAH-specific oral therapies that have been shown to be well tolerated in the pediatric population, sildenafil and bosentan, will result in better World Health Organization (WHO) functional class at 12 months after initiation of PAH treatment than therapy with sildenafil alone.
Gender:
ALL
Ages:
Between 3 months and 18 years
Trial Updated:
10/09/2024
Locations: Columbia University Medical Center, New York, New York
Conditions: Pediatric Pulmonary Hypertension
Monitoring Minimal Residual Disease of Patients with Acute Myelogenous Leukemia or High Grade Myelodysplastic Syndrome
Recruiting
This study is being performed to develop assays to determine the impact of the therapy patients receive for treatment of AML or MDS and to determine if these tests can identify those patients who are at a greater risk for having their disease relapse.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/09/2024
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome
Comprehensive Patient-Centered Home-based Care Coaching for COPD Self-management
Recruiting
The Icahn School of Medicine at Mount Sinai will conduct a randomized controlled trial of a self-management support intervention for predominantly minoritized and low-income adults with chronic obstructive pulmonary disease (COPD). The trial will focus on comprehensive screening and targeted management of barriers to COPD control, incorporating home-based pulmonary rehabilitation and oral steroid and antibiotic prescribing for pre-emptive treatment of COPD exacerbations. The research team will c... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
10/08/2024
Locations: Ichan School of Medicine at Mount Sinai, New York, New York
Conditions: Chronic Obstructive Pulmonary Disease