New York is currently home to 4474 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Natural History Study - Mitochondrial Disease
Recruiting
Carriers of the m.3242A\>G mutation often have clinical symptoms which can include migraines, seizures, strokes, hearing loss, balance issues, gastrointestinal issues, and many other symptoms. The investigators would like to learn more about these disorders and have designed a "Natural History Study" to monitor these conditions over time so that physicians and scientists can not only understand the problems that patients have, but work on developing treatments. The focus of the current work is t... Read More
Gender:
ALL
Ages:
4 years and above
Trial Updated:
10/28/2024
Locations: Columbia University, New York, New York
Conditions: MELAS or m.3243 A>G Mitochondrial DNA Mutation Carrier
Autologous Hair Follicle Derived Secretome as Adjunct to Aesthetic Procedures
Recruiting
Non-interventional, multi-site, prospective, open-label, observational, real-world study of autologous hair follicle secretome use.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
10/25/2024
Locations: Luxurgery, New York, New York
Conditions: Post Procedural Erythema
Testing the Role of Anti-fungal Therapy in Improving the Response to Therapies for Crohn's Disease
Recruiting
The goal of this clinical trial is to learn about the effects of fluconazole in patients who plan to start or are currently undergoing standard of care treatment and plan to dose-escalate an IL-23 therapy for their Crohn's disease. The main question it aims to assess is whether or not patient response to IL-23 therapies improve when simultaneously treated with fluconazole.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/24/2024
Locations: Weill Cornell Medicine, New York, New York
Conditions: Crohn's Disease, Inflammatory Bowel Diseases
(Neo)Adjuvant IDE196 (Darovasertib) in Patients With Localized Ocular Melanoma
Recruiting
Neoadjuvant/adjuvant IDE196 (darovasertib) in patients with primary uveal melanoma
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/24/2024
Locations: Northwell, Manhasset, New York
Conditions: Uveal Melanoma
PUSH-IT Continuing Enteral Feeds for Tracheostomy
Recruiting
The goal of this clinical trial is to evaluate nutrition administration in the time around the tracheostomy in patients with breathing tubes. The main questions it aims to answer are: * Will continuing nutrition up to the time of surgery (tracheostomy) decrease nutrition interruptions, thereby increasing food intake? * Does continuing nutrition up to the time of surgery increase instances of food going into the lungs or lung infections? Researchers will compare patients who have nutrition with... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/24/2024
Locations: Erie County Medical Center (University at Buffalo), Buffalo, New York
Conditions: Tracheostomy Complication, Critical Illness, Nutritional Deficiency
Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI
Recruiting
The study is a randomized trial of two different screening methods for early detection of liver cancer in patients with cirrhosis of the liver. The goal of PREMIUM is to compare an abbreviated version of the diagnostic gold standard for HCC (aMRI) +AFP to the standard-of-care screening (US+AFP) in patients at high risk of developing HCC. The investigators hypothesize that HCC will be detected at earlier stages, allowing for more curative treatments and resulting in a reduction in HCC-related mor... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
10/24/2024
Locations: James J. Peters VA Medical Center, Bronx, NY, Bronx, New York
Conditions: Carcinoma, Hepatocellular, Cirrhosis
Phase I Trial to Evaluate VLP Peanut in Healthy and Peanut Allergic Subjects
Recruiting
This phase I clinical trial is designed to evaluate the safety and tolerability of VLP Peanut in healthy subjects and in subjects with peanut allergy (PA). This clinical trial will evaluate the immunotoxicity profile of VLP Peanut in healthy subjects and assess the immunotoxicity profile and the degree of reactogenicity (allergenicity) in subjects with PA. This clinical trial will also explore preliminary proof of efficacy of VLP Peanut in subjects with PA.
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
10/24/2024
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Peanut Allergy
Longitudinal Study of Neurogenetic Disorders
Recruiting
The purpose of this study is to analyze patterns in individuals with hnRNP (and other) genetic variants, including their neurological comorbidities, other medical problems and any treatment. The investigators will maintain an ongoing database of medical data that is otherwise being collected for routine medical care. The investigators will also collect data prospectively in the form of questionnaires, neuropsychological assessments, motor assessments, and electroencephalography to examine the la... Read More
Gender:
ALL
Ages:
All
Trial Updated:
10/24/2024
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Neurodevelopmental Disorders, Intellectual Disability, Developmental Delay, Autism Spectrum Disorder, Seizures, Hypertonia, Muscle, Hypotonia
Upright MRI for Prostate Cancer Screening
Recruiting
This is an investigator initiated study to test the efficacy of an upright MRI (Magnetic Resonance Imaging) for the screening of prostate cancer. The purpose of this study is to compare Upright MRI as a technique to PSA (Prostate Specific Antigen) and current MRI imaging. It will take place at Mount Sinai Hospital, and last for a total of about 5 years. Eligible patients will be determined by the urologist. The target population is men who are at risk for prostate cancer, as determined by the ur... Read More
Gender:
MALE
Ages:
Between 18 years and 100 years
Trial Updated:
10/24/2024
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Prostate Cancer, Elevated PSA, Elevated Prostate Specific Antigen
Sevoflurane Concentrations in Children
Recruiting
The sevoflurane concentrations (as well as vital signs, child's date of birth, type of surgery) will be recorded during the first 10 minutes of anesthesia.
Gender:
ALL
Ages:
Between 2 years and 7 years
Trial Updated:
10/23/2024
Locations: John R. Oishei Children's Hospital, Buffalo, New York
Conditions: Anesthetic, Sevoflurane, Age
Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination with Pembrolizumab, in Unresectable Melanoma Patients
Recruiting
The trial aims to evaluate the efficacy of single agent L19IL2, single agent L19TNF, and combination L19IL2+L19TNF given concurrently with anti-PD1 therapy compared to historical control of anti-PD-1 re-challenge alone for anti-PD1 refractory unresectable stage III-IV melanoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/23/2024
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Melanoma Stage III, Melanoma Stage IV
Exactech Proximal Humerus Fracture Plate System Post Market Clinical Follow-up
Recruiting
The objective of this study is to collect and evaluate long-term clinical outcomes data in order to better understand the safety and performance of the Equinoxe Proximal Humerus Fracture Plates over time. This study will follow subjects for a period of up to 10 years post-surgery.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
10/23/2024
Locations: NYU Grossman School of Medicine, New York, New York
Conditions: Proximal Humeral Fracture, Fracture Dislocation, Non-Union Fracture