New York is currently home to 4476 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Kidney Precision Medicine Project
Recruiting
Acute kidney injury (AKI) and chronic kidney disease (CKD) impose a significant global health burden. Yet, no effective therapies currently exist for AKI, and only a few are available for CKD. Despite significant effort from industry and academia, development of pharmacologic therapies for AKI and CKD has been hampered by: Non-predictive animal models The inability to identify and prioritize human targets The limited availability of human kidney biopsy tissue A poor understanding of AKI and CK... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/18/2022
Locations: Columbia University, New York, New York
Conditions: Acute Kidney Failure, Acute Kidney Insufficiency, Acute Renal Failure, Acute Renal Injury, Acute Renal Insufficiency, Kidney Failure, Acute, Kidney Insufficiency, Acute, Renal Failure, Acute, Renal Insufficiency, Acute, Chronic Kidney Diseases, Chronic Kidney Insufficiency, Chronic Renal Diseases, Chronic Renal Insufficiency, Kidney Insufficiency, Chronic
KRT-232 in Combination With TL-895 for the Treatment of R/R MF and KRT-232 for the Treatment of JAKi Intolerant MF
Recruiting
This study evaluates KRT-232 in Combination With TL-895 for the Treatment of Relapsed or Refractory Myelofibrosis and KRT-232 for the Treatment of JAK Inhibitor Intolerant Myelofibrosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/05/2022
Locations: Memorial Sloan Kettering Cancer Center (MSKCC), New York, New York
Conditions: Myelofibrosis, Post-PV MF, Post-ET Myelofibrosis, Primary Myelofibrosis
Optical Coherence Tomography of the Saphenous Vein Graft
Recruiting
OCTOCAB is a prospective, randomized (1:1), single-center trial. The purpose of this study is to determine whether intravascular optical coherence tomography (OCT) guided saphenous vein grafting in coronary artery bypass surgery will reduce the rate of early vein graft failure (VGF).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/04/2022
Locations: St Francis Hospital, Roslyn, New York
Conditions: Coronary Bypass Graft Stenosis
Outcomes of Patients tReated wIth Mitral Transcatheter Edge-to-edge Repair for Primary Mitral Regurgitation Registry
Recruiting
This multinational, non-interventional, investigator-initiated, retrospective study aims to investigate outcomes of patients, who underwent mitral valve transcatheter edge-to-edge repair (M-TEER) for primary mitral regurgitation (PMR).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/11/2022
Locations: Montefiore Medical Center, New York, New York
Conditions: Mitral Regurgitation
The Leukemia and Lymphoma Society (LLS) National Research Registry
Recruiting
The Leukemia and Lymphoma Society (LLS) has built a National Research Registry to evaluate real world experiences and medical outcomes for people with blood cancer, before, during, and after blood cancer treatments.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
04/05/2022
Locations: Lymphoma and Leukemia Society, Rye Brook, New York
Conditions: Blood Cancer
Introducing Palliative Care (PC) Within the Treatment of End Stage Liver Disease (ESLD)
Recruiting
This is a comparative effectiveness study of two pragmatic models aiming to introduce palliative care for end stage liver disease patients. The 2 comparators are: Model 1: Consultative Palliative Care (i.e. direct access to Palliative Care provider), Model 2: Trained Hepatologist- led PC intervention (i.e. a hepatologist will receive formal training to deliver Palliative Care services) Primary Outcome: The change in quality of life from baseline to 3 months post enrollment as assessed by FACT-... Read More
Gender:
ALL
Ages:
Between 18 years and 120 years
Trial Updated:
04/05/2022
Locations: VA Bronx, Bronx, New York
Conditions: End Stage Liver Disease
Non Exudative AMD Imaged With SS-OCT- Extension
Recruiting
The investigators wish to better understand the role of the choriocapillaris (CC) in the formation and progression of non-exudative in age related macular degeneration (armd) by imaging the retinal pigment epithelium (rpe) and the choroidal microvasculature and by studying their inter-dependence to determine if the loss of the CC could prove useful as an anatomic clinical trial endpoint in future drug trials.
Gender:
ALL
Ages:
All
Trial Updated:
03/08/2022
Locations: Vitreous Retina Macular Consultants of NY, New York, New York
Conditions: Dry Macular Degeneration
Study of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199), With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL
Recruiting
The purpose of this study is to evaluate the efficacy and safety of acalabrutinib in combination with venetoclax and acalabrutinib in combination with venetoclax with and without obinutuzumab compared to chemoimmunotherapy in subjects with previously untreated CLL.
Gender:
All
Ages:
Between 18 years and 130 years
Trial Updated:
01/14/2022
Locations: Research Site, New York, New York
Conditions: Chronic Lymphocytic Leukemia
A Prospective Biomarker Study in Active SPMS Subjects Treated With Cladribine Tablets
Recruiting
The purpose of this study is to explore the concept that biomarker sensitivity will detect activity in Multiple Sclerosis (MS) subjects and allow appropriate change in treatment to prevent dysfunction.
Gender:
ALL
Ages:
Between 21 years and 65 years
Trial Updated:
01/12/2022
Locations: Multiple Sclerosis Center of Northeastern New York, P.C., Latham, New York
Conditions: Multiple Sclerosis
COVID-19 Administration of Single-Dose Subcutaneous Anti- Spike(s) SARS-CoV-2 Monoclonal Antibodies Casirivimab and Imdevimab in High-Risk Pediatric Participants Under 12 Years of Age
Recruiting
The primary objective of the study is to characterize the concentrations of casirivimab+imdevimab in serum over time after a single subcutaneous (SC) administration The secondary objectives of the study are: To assess the safety and tolerability of SC or single administration of casirivimab+imdevimab To assess the occurrence of grade ≥3 injection site reactions and grade ≥3 hypersensitivity reactions, in participants treated with SC doses of casirivimab+imdevimab To assess the immunogenicity o... Read More
Gender:
All
Ages:
12 years and below
Trial Updated:
12/06/2021
Locations: Jacobi Medical Center, Bronx, New York
Conditions: COVID-19
Early Feasibility Study of the Cardiac Implants Percutaneous Ring Annuloplasty System
Recruiting
An early feasibility study to evaluate the safety and performance of 1) the transcatheter delivery and implantation of the Cardiac Implants (CI) annuloplasty ring and 2) the adjustment of the ring approximately 90 days following implantation in patients suffering from ≥ moderate functional tricuspid regurgitation (FTR).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/18/2021
Locations: Weill Cornell Medicine-New York Presbyterian Hospital, New York, New York
Conditions: Tricuspid Regurgitation Functional
Delphi Early Feasibility Study
Recruiting
An early feasibility study to evaluate the safety and first pass effect technical assessment of Delphi Revascularization Device for clot retrieval in Anterior circulation ischemic stroke in the intracranial ICA, MCA M1 and proximal dominant MCA M2, up to 8hrs of symptom onset or Last Known Well (LKW).
Gender:
All
Ages:
18 years and above
Trial Updated:
08/19/2021
Locations: kaledia Health/Buffalo General Medical Center/GVI, Buffalo, New York
Conditions: Ischemic Stroke