New York is currently home to 4503 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Ribociclib and Bicalutamide in AR+ TNBC
Recruiting
This is an open label, multi-institutional, single arm phase II trial of ribociclib in combination with bicalutamide in advanced AR+ triple-negative breast cancer. No randomization or blinding is involved.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/10/2024
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Triple Negative Breast Cancer
Impella RP Flex with Smart Assist
Recruiting
To capture observational data of the Abiomed Impella RP Flex in a real-world setting.
Gender:
ALL
Ages:
All
Trial Updated:
10/09/2024
Locations: Montefiore Medical Center - Moses, Bronx, New York
Conditions: Right Ventricular (RV) Dysfunction
A Digitally Assisted Risk Reduction Platform for Youth At High Risk for Suicide
Recruiting
Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death among youth. Digital tools, especially personal smartphones, are promising avenues to address these issues and can be used to provide a unique understanding of risk factors, including psychological distress, anhedonia and behavioral withdrawal, and sleep disturbance among high-risk individuals. This project aims to enhance the effectiveness of the delivery of preventative health care to yo... Read More
Gender:
ALL
Ages:
Between 13 years and 18 years
Trial Updated:
10/09/2024
Locations: Columbia University, New York, New York
Conditions: Suicide, Mental Health Disorder, Anhedonia
How Hormones and Exposure and Response Prevention (EX/RP) Affect the Brain of People With OCD
Recruiting
Studies show that hormones affect the brain's fear extinction network, which is relevant for therapy involving exposure and response prevention (EX/RP), a first-line treatment for obsessive compulsive disorder (OCD). This study will examine the effect of delivering EX/RP to women during different phases in their menstrual cycle to determine the effects of hormones on the fear extinction network and on their OCD symptoms.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
10/09/2024
Locations: New York State Psychiatric Institute, New York, New York
Conditions: OCD
Mono vs. Dual Therapy for Pediatric Pulmonary Arterial Hypertension
Recruiting
The investigators' central hypothesis is that early combination therapy with two PAH-specific oral therapies that have been shown to be well tolerated in the pediatric population, sildenafil and bosentan, will result in better World Health Organization (WHO) functional class at 12 months after initiation of PAH treatment than therapy with sildenafil alone.
Gender:
ALL
Ages:
Between 3 months and 18 years
Trial Updated:
10/09/2024
Locations: Columbia University Medical Center, New York, New York
Conditions: Pediatric Pulmonary Hypertension
Monitoring Minimal Residual Disease of Patients with Acute Myelogenous Leukemia or High Grade Myelodysplastic Syndrome
Recruiting
This study is being performed to develop assays to determine the impact of the therapy patients receive for treatment of AML or MDS and to determine if these tests can identify those patients who are at a greater risk for having their disease relapse.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/09/2024
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome
Comprehensive Patient-Centered Home-based Care Coaching for COPD Self-management
Recruiting
The Icahn School of Medicine at Mount Sinai will conduct a randomized controlled trial of a self-management support intervention for predominantly minoritized and low-income adults with chronic obstructive pulmonary disease (COPD). The trial will focus on comprehensive screening and targeted management of barriers to COPD control, incorporating home-based pulmonary rehabilitation and oral steroid and antibiotic prescribing for pre-emptive treatment of COPD exacerbations. The research team will c... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
10/08/2024
Locations: Ichan School of Medicine at Mount Sinai, New York, New York
Conditions: Chronic Obstructive Pulmonary Disease
Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants with SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)
Recruiting
This is the study of AMT-162 in Participants with SOD1-ALS and is designed to evaluate the safety, tolerability, and exploratory efficacy of intrathecally administered gene therapy AMT-162. AMT-162-001 is a Phase 1/2, multi-center, single ascending dose study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Amyotrophic Lateral Sclerosis
RELAXaHEAD for Headache Patients (Phase III)
Recruiting
This study is a fully powered, remote randomized control trial to evaluate RELAXaHEAD in people with migraine.
Gender:
ALL
Ages:
Between 16 years and 80 years
Trial Updated:
10/08/2024
Locations: NYU Langone Health, New York, New York
Conditions: Migraine
Trial of Neratinib Plus Capecitabine in Subjects with HER2-Negative Metastatic Breast Cancer with Brain Metastases and Abnormally Active HER2 Signaling
Recruiting
The purpose of this research is to look at the safety and effectiveness of a HER2-targeted therapy neratinib when given with capecitabine, a chemotherapy, for breast cancer patients with brain metastases whose tumors were HER2-negative by standard tests but showed abnormal HER2 activity based on the CELsignia results.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: University of Rochester, Rochester, New York
Conditions: Breast Cancer
Exercise and Nutrition Interventions During Chemotherapy K07
Recruiting
Chemotherapy-induced peripheral neuropathy (CIPN) is a highly prevalent and severe side-effect of taxane chemotherapy, often used to treat breast cancer. Unfortunately there are very limited treatments for CIPN. This is a phase II randomized controlled trial to test the preliminary efficacy of exercise vs. nutrition education on CIPN, to systematically investigate the potential roles of inflammation and interoception, and to obtain data with a more accurate effect size to inform a future study.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Neuropathy;Peripheral
Treatment of Breast Fibroadenoma Targeted Tissue With HIFU
Recruiting
This study evaluates the efficacy and the safety of the HIFU for the treatment of breast fibroadenoma.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: Bellevue Hospital Center, New York, New York
Conditions: Breast Fibroadenoma