New York is currently home to 4503 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Decision Aid (DA) for Renal Patients
Recruiting
The objective of this study is to understand how patients make decisions about treating their kidney masses, and to identify key values and preferences for treating their kidney masses. The study team will develop a decision aid (DA) using the decision-analytic model to communicate personalized benefit/harm estimates to patients and promote patient-centered treatment of renal tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/25/2024
Locations: NYU Langone Health, New York, New York
Conditions: Kidney Tumor, Renal Cancer
taVNS for FRNS in Children
Recruiting
Children with frequently relapsing nephrotic syndrome (FRNS) are exposed to prolonged courses of steroids and other immunosuppressant medications. Given the adverse side effect profiles and variable efficacy of these medications, there is an urgent need to identify novel and safe therapies to treat nephrotic syndrome in children. Stimulation of the vagus nerve, which can be activated non invasively by transcutaneous auricular vagus nerve stimulation (taVNS), has immunomodulatory effects mediated... Read More
Gender:
ALL
Ages:
Between 3 years and 17 years
Trial Updated:
06/24/2024
Locations: Cohen Children's Medical Center, New Hyde Park, New York
Conditions: Nephrotic Syndrome in Children, Minimal Change Disease, Focal Segmental Glomerulosclerosis
A Pilot Trial of taVNS for SRNS in Children (kidNEY-VNS)
Recruiting
Children with steroid resistant nephrotic syndrome (SRNS) are exposed to prolonged courses of immunosuppressant medications. Given the adverse side effect profiles and variable efficacy of these medications, there is an urgent need to identify novel and safe therapies to treat nephrotic syndrome in children. Stimulation of the vagus nerve, which can be activated noninvasively by transcutaneous auricular vagus nerve stimulation (taVNS), has immunomodulatory effects mediated by the inflammatory re... Read More
Gender:
ALL
Ages:
Between 3 years and 17 years
Trial Updated:
06/24/2024
Locations: Cohen Children's Medical Center, New Hyde Park, New York
Conditions: Nephrotic Syndrome in Children, Minimal Change Disease, Focal Segmental Glomerulosclerosis
Study of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in Cholangiocarcinoma
Recruiting
This study is a Phase III, Randomized, Controlled, Global Multicenter Study to Evaluate the Efficacy and Safety of Oral Tinengotinib versus Physician's Choice in Subjects with Fibroblast Growth Factor Receptor (FGFR)-altered, Chemotherapy- and FGFR Inhibitor-Refractory/Relapsed Cholangiocarcinoma
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/21/2024
Locations: Roswell Park Comprehensive Cancer Center, Buffalo, New York
Conditions: Cholangiocarcinoma
Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)
Recruiting
The Study is a Phase 3, randomized, three-arm, double-blind, placebo-controlled, multi-regional clinical research study to evaluate the safety and efficacy use of toripalimab alone or in combination with tifcemalimab as consolidation therapy in patients with limited-stage small cell lung cancer without disease progression following chemoradiotherapy. Tifcemalimab is a monoclonal antibody against B and T lymphocyte attenuator (BTLA). Toripalimab is a monoclonal antibody against programmed death... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/19/2024
Locations: North Shore Hematology Oncology Associates DBA NY Cancer and Blood Specialists, New York, New York
Conditions: Limited-stage Small Cell Lung Cancer (LS-SCLC)
A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)
Recruiting
This is a first-in-human study evaluating the anti-T cell immunoglobulin and mucin containing protein-3 (TIM-3) antibody TSR-022. The study will be conducted in 2 parts with Part 1 consisting of dose escalation and Part 2 dose expansion. Part 1 will determine the recommended Phase 2 dose (RP2D) of TSR-022 and Part 2 will evaluate the antitumor activity of TSR-022 in combination with TSR-042 or docetaxel and as monotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/18/2024
Locations: GSK Investigational Site, Bronx, New York
Conditions: Neoplasms
Effects of MK-3475 (Pembrolizumab) on the Breast Tumor Microenvironment in Triple Negative Breast Cancer
Recruiting
Assess response to pembrolizumab in both primary tumor, normal breast stroma, circulating lymphocytes and serum exosomes in treatment naive triple negative breast cancer (TNBC) patients. Assess for change in tumor-infiltrating lymphocytes (TILS) both stromal (sTILS) and intraepithelial (iTILS) in newly diagnosed early stage TNBC patients treated with two doses of MK-3475 prior to lumpectomy.
Gender:
FEMALE
Ages:
Between 21 years and 80 years
Trial Updated:
06/17/2024
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Triple Negative Breast Cancer
The Effect of Omega-3 Fortified Smoothies on Omega-3 Index and Physical Performance Related Outcomes Among Soldiers
Recruiting
The goal of this clinical trial is to test the effect of omega-3 on physical performance and recovery of Soldiers. Objectives 1: Assess the impact of 8-weeks of daily consumption of 1600mg of omega-3 fortified smoothie on O3I response. Objective 2: Determine the relationship between O3I and measures of performance and recovery. Participants will: * Be randomly assigned to placebo group or to the omega-3 fortified smoothie group. * The intervention group will take omega-3 fortified smoothies... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
06/14/2024
Locations: Fort Drum, Fort Drum, New York
Conditions: Nutrition, Healthy
MTC Versus FMT in for RCDI
Recruiting
Investigating four different treatment of MTC or FMT
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/14/2024
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Clostridiodies Difficile Infections
Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine/Venetoclax in MDS and AML
Recruiting
Myeloid malignancies which include AML (acute myeloid leukemia) and MDS (myelodysplatic syndrome) are cancers of the bone marrow which lead to bone marrow failure. The bone marrow is the place or factory in the body where components of blood such as red cells, platelets and white cells are made. In bone marrow failure, the ability of the bone marrow to make these cells is decreased. The decreased bone marrow function is the result from abnormalities that develop in the malignant cells which prev... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/14/2024
Locations: Montefiore Medical Center, Bronx, New York
Conditions: MDS, AML, CMML
EXHIT ENTRE Implementation Trial of High Intensity Versus Low Intensity Strategy
Recruiting
This study is a multi-site, cluster randomized, two group implementation trial comparing a low- versus high-intensity implementation strategy for supporting hospital-based opioid use disorder treatment (HBOT) in community hospital settings where medication for opioid use disorder (MOUD) treatment has not been implemented.
Gender:
ALL
Ages:
All
Trial Updated:
06/14/2024
Locations: New York University, New York, New York
Conditions: Substance Use Disorders, Opioid Use Disorder, Severe, Opioid Use Disorder, Moderate
Blood Collection Biorepository for Liver Disease Research
Recruiting
The purpose of establishing a biorepository is to provide high quality specimens (serum, plasma, buffy coat and liver tissue) for future researchers who are studying the effects that fatty liver and viral diseases have on the liver.
Gender:
ALL
Ages:
7 years and above
Trial Updated:
06/14/2024
Locations: University at Buffalo, Buffalo General Medical Center, Buffalo, New York
Conditions: Non-Alcoholic Steatohepatitis(NASH), Hepatitis C, Hepatitis B, Fibrosis, Cirrhosis, Fatty Liver, Obesity, Childhood, Bariatric Surgery Candidate