New York is currently home to 4476 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies
Recruiting
This is a multi-center, open-label Phase 0 Master Protocol designed to study the localized pharmacodynamics (PD) of anti-cancer therapies within the tumor microenvironment (TME) when administered intratumorally in microdose quantities via the CIVO device in patients with surface accessible solid tumors for which there is a scheduled surgical intervention. CIVO stands for Comparative In Vivo Oncology. Multiple substudies will include specified investigational agents and combinations to be evaluat... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/15/2024
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Solid Tumor
Patient Reported Outcomes for Acute Asthma Care Treatment
Recruiting
Asthma affects 1 in every 12 persons in the U.S., resulting in 1.9 million ED visits annually; however, the impact of ED care on patient-reported outcomes after acute exacerbations is unknown. The proposed research will train a physician-scientist to develop a novel instrument to assess patient-reported outcomes after adult ED asthma visits, evaluate the association between ED clinical processes and patient-reported outcomes, and test the association between patient-reported outcomes and subsequ... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/15/2024
Locations: Mount Sinai Beth Israel, New York, New York
Conditions: Asthma
Knee Arthroplasty Activity Trial
Recruiting
Total knee replacement (TKR) is a common and costly procedure widely used to relieve pain and improve function in patients with symptomatic advanced knee osteoarthritis (OA). As of 2013, the annual incidence of TKR was over 680,000 surgeries and annual costs exceeded $11 billion. Growing evidence suggests that while pain and functional status improve following TKR, physical activity (PA) typically does not surpass pre-TKR levels. Engagement in PA can meaningfully improve quality of life (QoL), p... Read More
Gender:
ALL
Ages:
Between 40 years and 85 years
Trial Updated:
04/15/2024
Locations: University at Buffalo, Buffalo, New York
Conditions: Knee Osteoarthritis, Total Knee Replacement
A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD)
Recruiting
This is a double-blind, saline-controlled, and randomized study with blinded assessments using a single dose. Subjects that have a current diagnosis of chronic lumbar disc disease and meet eligibility criteria will be enrolled. Chronic lumbar disc disease is defined as back and/or radicular pain with degeneration of the disc confirmed by patient history, physical examination, and radiographic measures such as computed tomography (CT), magnetic resonance imaging (MRI), plain film, myelography, di... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
04/15/2024
Locations: Long Island Spine Rehabilitation Medicine, East Meadow, New York
Conditions: Lumbar Disc Disease
Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission
Recruiting
The purpose of this study is to compare the effectiveness and safety of a strategy of switching to an alternative targeted immunomodulator (TIM) therapy to treat to a target of endoscopic remission, versus continuing index TIM in patients with inflammatory bowel disease (IBD) (Crohn's disease or ulcerative colitis \[UC\]) in symptomatic remission with moderate to severe endoscopic inflammation despite optimization of index TIM in a real-world setting.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/12/2024
Locations: Saratoga Schenectady Gastroenterology Associates, Burnt Hills, New York
Conditions: Ulcerative Colitis, Crohn Disease
Quality of Pediatric Resuscitation in a Multicenter Collaborative
Recruiting
This is a prospective, observational, multi-center cohort study of pediatric cardiac arrests. The purpose of the study is to determine the association between chest compression mechanics (rate, depth, flow fraction, compression release) and patient outcomes. In addition, the investigators will determine the association of post cardiac arrest care with patient outcomes.
Gender:
ALL
Ages:
Between 0 years and 17 years
Trial Updated:
04/12/2024
Locations: Albany Medical Center, Albany, New York
Conditions: Cardiac Arrest, Cardiopulmonary Arrest
Expanding the Potential of Couples HIV Testing: Adjunct Modules to Reduce Drug Use Among Vulnerable Male Couples
Recruiting
This study utilizes a randomized controlled trial design to evaluate the efficacy of two intervention components for couples HIV testing and counseling (CHTC): a communication skills training video and a substance use module. Participants are randomized in a full-factorial design to one of 4 conditions: CHTC as usual; CHTC + communication skills training videos; CHTC + substance use module; or CHTC plus both adjunct components.
Gender:
MALE
Ages:
Between 17 years and 29 years
Trial Updated:
04/11/2024
Locations: Hunter College, New York, New York
Conditions: Substance Use, HIV Infections
Eversense® Non-adjunctive Use Post Approval Study
Recruiting
This is a non-blinded, prospective, multi-center, single arm longitudinal cohort study (patient serving as their own control), to evaluate the effectiveness of diabetes with the Eversense CGM System non-adjunctively compared to self-monitoring of blood glucose (SMBG) using a blood glucose (BG) meter in participants with either Type 1 or Type 2 diabetes. Subjects will serve as their own control, with their baseline based on using SMBG to manage their diabetes for the first 6 months followed by us... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/11/2024
Locations: Endocrine Associates of West Village, Long Island City, New York
Conditions: Diabetes
Real World Evidence Clinical Utility Study of KidneyIntelX
Recruiting
The purpose of this study is to assess the impact of the KidneyIntelX assay utilized as part of the current standard of care on the management of patients seen in the primary care physician's office at Mount Sinai.
Gender:
ALL
Ages:
23 years and above
Trial Updated:
04/11/2024
Locations: Mount Sinai Health System, New York, New York
Conditions: Chronic Kidney Diseases, Diabetic Kidney Disease
Decision Impact Trial of KidneyIntelX
Recruiting
The current trial is designed to evaluate how the results of KidneyIntelX test impacts on the clinical management of type 2 diabetes patients identified as increased risk for rapid kidney function decline within 5-years.
Gender:
ALL
Ages:
23 years and above
Trial Updated:
04/11/2024
Locations: Delmar Family Medicine, Slingerlands, New York
Conditions: Diabetic Kidney Disease
Early Feeding After Oral Cavity Reconstruction
Recruiting
This is a prospective single-arm non-inferiority trial evaluating surgical outcomes in subjects who are fed in the first days after oral cavity reconstructive surgery. The purpose of the study is to specifically compare the rates of orocutaneous fistula in subjects who are allowed to eat immediately after surgery to those rates published in the literature (individuals for whom oral feeding is delayed for several days after surgery). Eighty nine subjects who will undergo oral cavity reconstructiv... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/10/2024
Locations: Mount Sinai Health System, New York, New York
Conditions: Head and Neck Cancer, Free Tissue Transfer
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
Recruiting
This clinical trial keeps track of and collects follow-up information from patients who are currently enrolled on or have participated in a Children's Oncology Group study. Developing a way to keep track of patients who have participated in Children's Oncology Group studies may allow doctors learn more about the long-term effects of cancer treatment and help them reduce problems related to treatment and improve patient quality of life.
Gender:
ALL
Ages:
All
Trial Updated:
04/10/2024
Locations: Albany Medical Center, Albany, New York
Conditions: Hematopoietic Cell Transplantation Recipient, Leukemia, Solid Tumor