New York is currently home to 4503 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia
Recruiting
Purpose of the study: Evaluate the effect of deep repetitive transcranial magnetic stimulation (deep rTMS; hereafter abbreviated as "dTMS") on synaptic density measured with positron emission tomography (PET) and the radiotracer \[11C\]UCB-J. The investigators also seek to link plasticity changes in the regions targeted by the electric field (especially, the insula) to changes in the functioning of insula circuits and behavioral cigarette usage in patients with schizophrenia (SCZ). Importance o... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
04/23/2024
Locations: Stony Brook University, Stony Brook, New York
Conditions: Schizophrenia, Smoking Cessation, Tobacco Use
The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis
Recruiting
ME\&MG is a standalone software (digital solution) running on patients smartphones, connected to a web portal for physicians. It is intended to be used as an unsupervised digital self-assessment tool for the monitoring of disabilities in patients living with MG. ME\&MG contains digital active tests for the assessment of ptosis, breathing, dysarthria, upper- and lower-limb (arms and legs) weakness, treatment follow-up, and validated e-questionnaires related to daily activities, pain, fatigue, sl... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
04/23/2024
Locations: Neurological Associates of Long Island, P.C., Lake Success, New York
Conditions: Myasthenia Gravis
OCT Eccentric Fixation and Amblyopia in Children
Recruiting
The objectives of this proposal are to characterize the relationship between OCT eccentric fixation (OCT-EF), fixation eye movement (FEM), macular sensitivity in children with amblyopia.
Gender:
ALL
Ages:
Between 4 years and 16 years
Trial Updated:
04/20/2024
Locations: SUNY College of Optometry, New York, New York
Conditions: Amblyopia
Study to Assess SLN124 in Patients With Polycythemia Vera
Recruiting
This is a Phase 1/2, multicenter study with an open-label dose escalation followed by a randomized placebo controlled and double-blind phase of SLN124 in adult patients with Polycythemia Vera (PV) to assess the safety, tolerability, efficacy, pharmacokinetic (PK), and Pharmacodynamic (PD) response of SLN124.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/19/2024
Locations: Mount Sinai Hospital, New York, New York
Conditions: Polycythemia Vera
Telehealth Intervention for Autism Spectrum Disorder
Recruiting
Autism Spectrum Disorder (ASD) is one of the most frequently occurring childhood-onset neurodevelopmental disorders affecting 1 in every 54 children. Most children with ASD experience challenges participating in daily activities (e.g.: eating, sleeping, bathing, grooming, playing, etc.) and receive occupational therapy intervention to address these. The COVID-19 pandemic has restricted in-person therapy for many of these children and there is an urgent need for evidence-based, validated teleheal... Read More
Gender:
ALL
Ages:
Between 4 years and 12 years
Trial Updated:
04/19/2024
Locations: Rose R. Kennedy Children's Evaluation and Rehabilitation Center (CERC) at Montefiore, Bronx, New York
Conditions: Autism Spectrum Disorder
DB RCT for Specialized Phototherapy in Parkinson's Disease.
Recruiting
This is a pivotal study to determine whether light therapy can improve non-motor and motor function in Parkinson's disease, on top of current best medical treatment.
Gender:
ALL
Ages:
45 years and above
Trial Updated:
04/19/2024
Locations: University of Rochester, Rochester, New York
Conditions: Parkinson Disease
Development of a Multi-sensory Rehabilitation Program for People With Ultra Low Vision
Recruiting
This research is aimed to address one of the big gaps in the current vision rehabilitation protocols for people with profound visual impairment by evaluating a multisensory approach. There are a growing number of clinical trials that recruit people with end-stage eye diseases and the rehabilitation plan following various treatments is not clear. It is important to address this in order to maximize the efficacy of such treatments and to improve the quality of life in people with profound visual i... Read More
Gender:
ALL
Ages:
Between 12 years and 99 years
Trial Updated:
04/18/2024
Locations: SUNY College of Optometry, New York, New York
Conditions: Low Vision Blindness, Visual Impairment, Quality of Life, Functional Visual Loss
The Effects of a Home-Based Fall Prevention Program on Community-Dwelling Elderly's Fall Risk Category
Recruiting
The primary goal of this dissertation study is to determine if a home-based multiplanar balance training program with electronic assistance, will be effective in reducing one's fall risk category. Hypothesis: After 12 weeks, there will be a statistically significant decrease in the fall risk category for individuals in a home-based multiplanar balance training and educational program with electronic assistance as compared to no change in the fall risk category for individuals in an educational... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
04/17/2024
Locations: Metro PT, New York, New York
Conditions: Fall Risk
Phase 2A Pilot C3 Trial of Recurrent/Refractory Metastatic Advanced Pancreatic Cancer
Recruiting
The goals of this trial are: 1) To evaluate the safety and tolerability of C3 administration with Gemcitabine; and 2) To assess the disease response following C3 administration with Gemcitabine. The main question it aims to answer are: 1) Is C3 in combination with Gemcitabine safe, tolerable, and effective for reducing improving advanced stage pancreatic cancer? and 2) Can C3 in combination with Gemcitabine prolong the lives of patients with advanced stage pancreatic cancer. Participants will re... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: SUNY Downstate Health Sciences University, Brooklyn, New York
Conditions: Pancreatic Cancer Metastatic
Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2
Recruiting
The objective of this study is to compare the safety and efficacy of RGN-259 to placebo for the treatment of Neurotrophic Keratopathy (NK)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Neurotrophic Keratopathy
Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation
Recruiting
This study will evaluate the safety of infusion of the investigational cord blood units by carefully documenting all infusion-related problems.
Gender:
ALL
Ages:
All
Trial Updated:
04/17/2024
Locations: Northwell Health - North Shore University Hospital, Lake Success, New York
Conditions: Infusion Reactions
OCT Evaluation of Neurotrophic Ulcer Following Treatment With Oxervate
Recruiting
Neurotrophic keratitis (NK) is a condition where the cornea, or clear outer covering of the eye, has reduced sensation due to a variety of reasons. In more advanced cases of NK, the cornea can develop an area of thinning called an ulcer. The purpose of this research is to find out if Oxervate (cenegermin-bkbj 0.002%) an FDA-approved treatment for neurotrophic corneal ulcers leads to an increase in thickness of the corneal stroma (middle layer of the cornea) during and after treatment of a neurot... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/16/2024
Locations: SightMD, Manhasset, New York
Conditions: Neurotrophic Ulcer, Neurotrophic Keratitis, Neurotrophic Corneal Ulcer, Neurotrophic Keratoconjunctivitis