New York is currently home to 4503 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF
Recruiting
The goal of the study is to examine multiple markers of anthropometrics, body composition, sarcopenia and frailty and compare them to dual energy X-ray absorptiometry (DXA) output, which is considered the current clinical gold-standard tool to measure body composition. The result of this study will provide detailed data regarding the nutrition and body composition within this Cystic Fibrosis population and also provide a baseline evaluation for use of these biomarkers in the future studies inclu... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/05/2025
Locations: New York Medical College (NYMC), Hawthorne, New York
Conditions: Cystic Fibrosis
Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Recruiting
Ifetroban prevents and treats lung fibrosis due to multiple causes (bleomycin, genetic, radiation). The safety and efficacy of oral ifetroban will be assessed in patients with IPF.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
08/05/2025
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Idiopathic Pulmonary Fibrosis
A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors
Recruiting
The purpose of this clinical trial is to learn the safety and effects of the study medicine (PF-07799544) administered as a single agent and in combination with other study medications in people with solid tumors. This study is seeking participants who have an advanced solid tumor for which the available treatments are no longer effective in controlling their cancer. All participants in this study will receive PF-07799544. PF-07799544 comes as a tablet to take by mouth daily (initially 2 times p... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
08/05/2025
Locations: Optum Medical Care, PC, Brewster, New York
Conditions: Melanoma, Glioma, Thyroid Cancer, Non-Small Cell Lung Cancer, Malignant Neoplasms, Brain Neoplasms, Colorectal Cancer
A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.
Recruiting
A Dose Finding Study of \[177Lu\]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination with Standard of Care and in Recurrent Glioblastoma as a Single Agent
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
08/05/2025
Locations: Col Uni Med Center New York Presby, New York, New York
Conditions: Glioblastoma
A Randomized Trial of a Mobile Health Exercise Intervention for Older Adults With Myeloid Neoplasms
Recruiting
This is a phase 2 randomized controlled trial (RCT) to assess the preliminary efficacy of the a mobile health exercise intervention (GO-EXCAP) versus a chemotherapy education control in 100 older patients with MN receiving outpatient chemotherapy on physical function and patient-reported outcomes (fatigue, mood, and quality of life). We will also explore the effect of the intervention on TNFα and related cytokine gene promoter methylation and their gene and protein expression.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
08/05/2025
Locations: University of Rochester Medical Center/Wilmot Cancer Institute, Rochester, New York
Conditions: Cancer, Myeloid Neoplasm
HER2-specific Chimeric Antigen Receptor (CAR) T Cells for Children With Ependymoma
Recruiting
This is a Phase I study to evaluate the safety profile of a type of immune therapy called HER2 CAR T cells (short for HER2 chimeric antigen receptor T cells). In addition to looking for side effects, we will study how well this treatment works against a brain tumor called ependymoma that has come back after treatment (recurrent) or has not responded well to treatment (progressive) in children. The HER2 CAR T cells used in this trial are made from the patient's own blood. A new gene, called the H... Read More
Gender:
ALL
Ages:
Between 1 year and 22 years
Trial Updated:
08/05/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Ependymoma
Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors
Recruiting
This is an open-label, dose escalation and expansion study to evaluate the safety, tolerability, PK, and biological activity of VT3989 administered, alone or in combination, once daily in patients with mesothelioma and/or metastatic solid tumors that are resistant to standard therapy or for which no effective standard therapy is available.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/05/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Solid Tumor, Adult, Mesothelioma, NSCLC
Citadel Embolization Device Study
Recruiting
The purpose of this study is to gather safety and effectiveness data on Stryker Neurovascular's Next Generation Target Detachable Coil (hereafter referred to as the Citadel Embolization Device), when used with Target Detachable Coils, in the treatment of wide-neck intracranial aneurysms.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/05/2025
Locations: Weill Cornell, New York, New York
Conditions: Unruptured Wide-neck Aneurysms
Oral Iron in Children With Chronic Kidney Disease
Recruiting
This is a pilot clinical trial of oral iron therapy in children with chronic kidney disease (CKD) and mild anemia. Eligible children will be randomized into a standard of care (iron sulfate) arm vs. no iron therapy arm for 3 months. The outcomes will include muscle strength, physical activity, and changes in eating behavior, which will be measured at enrollment and at the end of the study period.
Gender:
ALL
Ages:
Between 1 year and 21 years
Trial Updated:
08/05/2025
Locations: Weill Cornell Medicine / New York Presbyterian Hospital, New York, New York
Conditions: Chronic Kidney Insufficiency, Chronic Kidney Diseases
Early Cochlear Implant Use
Recruiting
This observational study will examine newly activated cochlear implant users and determine whether their abilities to discern simple sounds change and relate to improved speech perception. Take-home computers and test-equipment will be sent home, and subjects will complete approximately 25 test sessions over the first 3 months of cochlea implant use. Then, subjects will be tested 3 more times in the laboratory until 1 year-post activation. The primary objective is to determine and quantify how s... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
08/04/2025
Locations: NYU Langone Health, New York, New York
Conditions: Cochlear Implant Users
A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease
Recruiting
This is a Phase 2, multicenter, platform study in adult participants with IBD (moderately to severely active Crohn's Disease or Ulcerative Colitis). The primary goal of this study is to assess the safety and efficacy of multiple investigational drugs.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/04/2025
Locations: Mirador Therapeutics Selected Site, Rochester, New York
Conditions: Inflammatory Bowel Disease (IBD), Ulcerative Colitis (UC), Crohn's Disease
Inspire UAS High Apnea Hypopnea Index (AHI)/High Body Mass Index (BMI) Post-Approval Study
Recruiting
The purpose of this observational clinical study is to provide evaluation of long-term safety and effectiveness in a newly expanded patient population including patients with a higher AHI and a higher BMI.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/04/2025
Locations: University of Rochester, Rochester, New York
Conditions: Obstructive Sleep Apnea (OSA)