Wisconsin is currently home to 1280 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Milwaukee, Madison, Green Bay and Marshfield. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee
NCT03588975
Recruiting
The objective of this study is to compare the efficacy and safety of MACI® vs arthroscopic microfracture in the treatment of patients aged 10 to 17 years with symptomatic articular chondral or osteochondral defects of the knee.
Gender:
ALL
Ages:
Between 10 years and 17 years
Trial Updated:
11/26/2024
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Chondral Defect, Articular Cartilage Defect, Articular Cartilage Disorder of Knee, Osteochondritis Dissecans (OCD)
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A Study of Brepocitinib in Adults With Active, Non-Infectious, Non-Anterior Uveitis
NCT06431373
Recruiting
The purpose of this study is to determine the safety and efficacy of brepocitinib in participants with active, non-anterior (intermediate, posterior, or pan) non-infectious uveitis (NIU).
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
11/25/2024
Locations: Clinical Trial Site, Madison, Wisconsin
Conditions: Uveitis, Posterior, Uveitis, Intermediate, Uveitis
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Auricular Neurostimulation for Chemotherapy Induced Nausea and Vomiting
NCT05143554
Recruiting
This study evaluates the efficacy of auricular percutaneous electrical nerve field stimulator in children, adolescents and young adults with chemotherapy induced nausea and vomiting.
Gender:
ALL
Ages:
Between 4 years and 30 years
Trial Updated:
11/25/2024
Locations: Children's Wisconsin Hospital, Milwaukee, Wisconsin
Conditions: Chemotherapy-induced Nausea and Vomiting
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Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures At High Risk of Infection: TOBRA
NCT04597008
Recruiting
The overall objective is to compare the effect of Vancomycin and Tobramycin powder combined (treatment) to Vancomycin powder (control) in the reduction of post-fixation infections of tibial plateau and tibial pilon fractures at high risk of infection (collectively considered the "study injuries").
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
11/25/2024
Locations: University of Wisconsin, Madison, Wisconsin
Conditions: Post Operative Surgical Site Infection
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Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
NCT03860883
Recruiting
Patients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin. There is evidence that less radical margins of excision may be just as safe. This is a randomised controlled trial of 1 cm versus 2 cm margin of excision of the primary lesion for adult patients with stage II primary invasive cutaneous melanomas (AJCC 8th edition) to determine differences in disease-free survival. A reduction in margins is expected to improve patient quality of... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/25/2024
Locations: University of Winsconsin Carbone Cancer Center-Eastpark medical Center, Madison, Wisconsin
Conditions: Cutaneous Melanoma, Stage II
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Preventing Obstetric Complications With Dietary Intervention
NCT06320054
Recruiting
The goal of this study is to learn whether access to healthy and fresh food, health coaching, and nutrition support intervention can reduce adverse birth outcomes in pregnant women. The main questions it aims to answer are: * Does access to healthy and fresh food, health coaching and nutrition support reduce the risk of gestational diabetes or preeclampsia and ultimately improve health outcomes for mothers and their newborns? * Are participants able to successfully utilize the health program? A... Read More
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
11/22/2024
Locations: Froedert & The Medical College of Wiscosin, Milwaukee, Wisconsin
Conditions: Gestational Diabetes, Gestational Hypertension, High Risk Pregnancy, Preeclampsia
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A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer
NCT06103864
Recruiting
This is a Phase III, randomised, open-label, 3-arm, multicentre, international study assessing the efficacy and safety of Dato-DXd with or without durvalumab compared with investigator's choice chemotherapy in combination with pembrolizumab in participants with PD-L1 positive locally recurrent inoperable or metastatic TNBC.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/22/2024
Locations: Research Site, Madison, Wisconsin
Conditions: Breast Cancer
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A Platform Study of Novel Immunotherapy Combinations as First-Line Treatment in Participants With PD-L1 Positive Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck- GALAXIES H&N-202
NCT06062420
Recruiting
The primary purpose of the study is to evaluate the antitumor activity and safety of novel immunotherapy combinations compared with dostarlimab in participants with Programmed death ligand 1 (PD-L1) positive Recurrent/Metastatic (R/M) Head and Neck Squamous Cell Carcinoma (HNSCC).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/22/2024
Locations: GSK Investigational Site, Milwaukee, Wisconsin
Conditions: Neoplasms, Head and Neck
Register for Updates
Orthosis to Improve Trunk Control in Infants Age 6-18 Months
NCT06027580
Recruiting
The purpose of this study is to determine the impact of the SPIO® Core-MAX® Expedition orthosis on an infant's head, trunk and upper limb function.
Gender:
ALL
Ages:
Between 6 months and 18 months
Trial Updated:
11/22/2024
Locations: Medical College of Wisconsin/Children's Wisconsin, Milwaukee, Wisconsin
Conditions: Cerebral Palsy
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Venetoclax to Augment Epigenetic Modification and Chemotherapy
NCT05317403
Recruiting
The investigator is testing the addition of venetoclax to 5-azacitidine and vorinostat followed by standard chemotherapy to enhance treatment response in AML patients.
Gender:
ALL
Ages:
Between 1 year and 25 years
Trial Updated:
11/22/2024
Locations: Children's Wisconsin, Milwaukee, Wisconsin
Conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory
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Preeclampsia Postpartum Antihypertensive Treatment
NCT04298034
Recruiting
The goal of this study is to compare whether antihypertensive treatment in the postpartum period decreases postpartum hypertension and its associated maternal morbidity, including risk of readmission and healthcare utilization in comparison with no treatment. Women with preeclampsia diagnosed during the antepartum, intrapartum or postpartum period will be randomized to either initiate antihypertensive treatment or standard of care. We hypothesize that postpartum antihypertensive treatment of pat... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
11/22/2024
Locations: Medical College of Wisconsin-Froedtert Hospital, Milwaukee, Wisconsin
Conditions: Preeclampsia, Hypertension in Pregnancy
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Differences in Postoperative Symptoms With Four Ureteral Stents
NCT06083051
Recruiting
This is a prospective randomized controlled trial designed to assess the differences in postoperative symptoms related to placement of a 6Fr Percuflex ureteral stents, 6Fr Tria ureteral stents, 4.8Fr Percuflex ureteral stents, and 4.8Fr Tria ureteral stents after ureteroscopy with laser lithotripsy for treatment of upper tract urinary stones. 272 participants will be enrolled and will be on study for up to approximately 10 weeks.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
11/21/2024
Locations: University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
Conditions: Urinary Stone
Register for Updates