Wisconsin is currently home to 1266 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Milwaukee, Madison, Green Bay and Marshfield. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Hypofractionated vs Conventional Fractionated RT in Soft Tissue Sarcomas
NCT05109494
Recruiting
This research study is designed to find out if radiation therapy treatment prior to surgery is safe and effective to treat soft tissue sarcomas. 30 participants with soft tissue sarcoma will be enrolled and can expect to be on study for up to 5 years.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/16/2024
Locations: University of Wisconsin Hospital and Clinics, Madison, Wisconsin
Conditions: Soft Tissue Sarcoma
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A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer
NCT04831580
Recruiting
This is a randomized controlled trial to compare survival for patients who undergoe robotic assisted laparoscopy versus open hysterectomy and lymph node assessment for the treatment of early stage cervical cancer.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/16/2024
Locations: University of Wisconsin Clinical Science Center, Madison, Wisconsin
Conditions: Cervical Cancer
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Endovascular Engineering ENGULF Study
NCT05597891
Recruiting
Evaluation of initial safety and clinical feasibility of the Hēlo PE Thrombectomy System for thrombectomy in acute submassive pulmonary embolism (PE).
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
12/13/2024
Locations: Gundersen Health, La Crosse, Wisconsin
Conditions: Pulmonary Embolism
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ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND)
NCT05388708
Recruiting
ASCEND researchers are partnering with families of children who receive extracorporeal membrane oxygenation (ECMO) after a sudden failure of breathing named pediatric acute respiratory distress syndrome (PARDS). ECMO is a life support technology that uses an artificial lung outside of the body to do the lung's work. ASCEND has two objectives. The first objective is to learn more about children's abilities and quality of life among ECMO-supported children in the year after they leave the pediatr... Read More
Gender:
ALL
Ages:
Between 14 days and 20 years
Trial Updated:
12/11/2024
Locations: UW Health American Family Children's Hospital, Madison, Wisconsin
Conditions: Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation
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Computer-guided Action Planning to Support Physical Activity (CAPPA) for Employees with Chronic Knee Symptoms
NCT06734052
Recruiting
The goal of this clinical trial is to learn if a brief health coaching intervention based on an approach known as brief action planning + Fitbit can increase physical activity in employees with chronic knee symptoms who work for Advocate Aurora Health. The main questions it aims to answer are: * Will a greater proportion of people in the health coaching intervention increase physical activity to at least 150 minutes of moderate-to-vigorous physical activity per week than a group of people with... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/10/2024
Locations: Marquette University, Milwaukee, Wisconsin
Conditions: Osteoarthritis of Knee, Knee Pain Chronic
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Multi-session, Personalized Cognitive Bias Modification for Thought-Action-Fusion
NCT06731426
Recruiting
Thought-Action-Fusion (TAF) is a cognitive bias that posits (1) having unwanted thoughts is morally equivalent to acting upon the thoughts (TAF-Moral; e.g., "Thinking about harming a child is as immoral as actually harming a child") and (2) having unwanted thoughts will increase the likelihood of the thoughts happening in real life (TAF-Likelihood; e.g., "My mother will get into a car accident, because I thought about it"). Given its central role in the development and maintenance of OCD, TAF ha... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/09/2024
Locations: UWM Anxiety Disorders Laboratory, Milwaukee, Wisconsin
Conditions: OCD
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Mechanisms Preventing Pharyngeal Reflux
NCT05696184
Recruiting
The overall goal is to define and characterize the manometric characteristics of UES incompetence associated with objectively documented pharyngeal reflux. The investigators will use endoscopic reflux detection as gold standard.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
12/06/2024
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: GERD
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Diagnostic Tests in Supra-Esophageal Gastroesophageal Reflux Disease (SE-GERD)
NCT05695846
Recruiting
After defining the manometric characteristics of UES incompetence associated with documented pharyngeal reflux, we will determine the reproducibility of manometric criteria for UES incompetence in prevention of pharyngeal reflux. We hypothesize that these criteria are comprised of either a single or constellation of manometric abnormalities. After determining the ability of externally applied cricoid cartilage pressure in preventing pharyngeal reflux, we further hypothesize that this approach wi... Read More
Gender:
ALL
Ages:
Between 20 years and 85 years
Trial Updated:
12/06/2024
Locations: Reza Shaker, Milwaukee, Wisconsin
Conditions: Gastroesophageal Reflux
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A Pilot Study of Local Anesthesia for Inguinal Hernia Surgery in Older Adults
NCT04706026
Recruiting
Inguinal hernia repair-the most common general surgery operation in the U.S.-provides a unique opportunity to improve outcomes for older patients by changing surgical practice. Nearly 80% of inguinal hernia operations are performed under general anesthesia versus 15-20% using local anesthesia, despite the absence of evidence for superiority. The choice of anesthesia has particular implications for older adults because they face substantial short- and long-term risk of cognitive and physical decl... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
12/06/2024
Locations: University of Wisconsin, Madison, Wisconsin
Conditions: Inguinal Hernia, Anesthesia, Local
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Brain Oxygen Optimization in Severe TBI, Phase 3
NCT03754114
Recruiting
BOOST3 is a randomized clinical trial to determine the comparative effectiveness of two strategies for monitoring and treating patients with traumatic brain injury (TBI) in the intensive care unit (ICU). The study will determine the safety and efficacy of a strategy guided by treatment goals based on both intracranial pressure (ICP) and brain tissue oxygen (PbtO2) as compared to a strategy guided by treatment goals based on ICP monitoring alone. Both of these alternative strategies are used in s... Read More
Gender:
ALL
Ages:
14 years and above
Trial Updated:
12/06/2024
Locations: Froedtert Hospital, Milwaukee, Wisconsin
Conditions: Brain Injuries, Traumatic
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Screening in Trauma for Opioid Misuse Prevention - an Adaptive Intervention
NCT06527599
Recruiting
The primary objective of the present pilot, sequential, multiple-assignment randomized trial (Pilot SMART) is to determine feasibility and acceptability of delivering (from the perspective of the treatment/intervention staff) and receiving (from the perspective of the patient) an adaptive intervention for reducing rates of opioid misuse and preventing development of opioid use disorder in individuals hospitalized for traumatic injury. A complimentary secondary objective is to ensure the feasibil... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/05/2024
Locations: UW Health, Madison, Wisconsin
Conditions: Opioid Misuse, Trauma Injury
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The TELENEO Trial: a Multicenter Trial of Telemedicine for Advanced Neonatal Resuscitations in Community Hospitals
NCT06087224
Recruiting
The purpose of this study is to evaluate the impact of real-time audio-video telemedicine consults with a neonatologist (termed teleneonatology) on the early health outcomes of at-risk neonates delivered in community hospitals.
Gender:
ALL
Ages:
0 days and above
Trial Updated:
12/05/2024
Locations: Prairie Ridge Health, Columbus, Wisconsin
Conditions: Death; Neonatal, Morbidity;Newborn
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