There are currently 165 active clinical trials seeking participants for Hypertension research studies. The states with the highest number of trials for Hypertension participants are California, Florida, Texas and Ontario.
Community-engaged Hypertension Prevention Program in Black Men
NCT05447962
Recruiting
The CLIP program will train Community Health Workers (CHWs) to screen and identify Black men with elevated blood pressure (BP) or stage 1 hypertension (HTN), initiate lifestyle counseling; and link them to primary care and social services.
Gender:
Male
Ages:
Between 18 years and 85 years
Trial Updated:
08/30/2023
Locations: NYU Langone Health, New York, New York
Conditions: Hypertension
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2 Weeks of Citrulline Supplementation on Arterial Function in Postmenopausal Women With Elevated Blood Pressure or Hypertension
NCT06025383
Recruiting
The objective of this project is to elucidate the effect of L-Citrulline (L-CIT) supplementation on vascular function at rest and during rhythmic handgrip exercise and functional sympatholysis via lower-body negative pressure in postmenopausal women with elevated blood pressure and hypertension.
Gender:
Female
Ages:
Between 50 years and 70 years
Trial Updated:
08/29/2023
Locations: Texas Tech University, Lubbock, Texas
Conditions: Menopause, Hypertension
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Targeting Endoplasmic Reticulum Stress in Human Hypertension
NCT06025630
Recruiting
There is strong evidence suggesting that endoplasmic reticulum stress contributes to neurogenic and vascular hypertension in various animal models, however this has never been explored in humans. Therefore, this project will fill this gap by performing a single-blind, placebo-controlled trial in humans with hypertension.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
08/29/2023
Locations: University of North Texas Health Science Center, Fort Worth, Texas
Conditions: Hypertension
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Technology-enabled Management Versus Usual Care for Blood Pressure
NCT05479461
Recruiting
Two arm parallel randomized clinical trial
Gender:
All
Ages:
Between 30 years and 90 years
Trial Updated:
08/27/2023
Locations: Stanford Health Care, Palo Alto, California
Conditions: Hypertension
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Study of Disrupted Sleep in Somali Americans
NCT05411029
Recruiting
The aims of this study are to determine the types and severity of previously undiagnosed sleep deficiencies in otherwise healthy Somali Americans, apply a research framework to define psychosocial, behavioral, environmental, and biological mechanisms mediating sleep deficiencies in Somali Americans, and examine the relationship between sleep deficiencies and increased blood pressure in Somali Americans.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
08/25/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Hypertension, Sleep Disorder, Healthy
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Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)
NCT04838678
Recruiting
The purpose of this study is to understand how the nervous system communicates to blood vessels to increase blood pressure during stress. The study will also investigate how hypertension and obesity influence the nervous system and vascular function. The study will involve measuring sympathetic nervous system activity and blood flow during common laboratory physiological stress protocols (e.g. hypoxia, exercise), and in response to infusion of drugs that cause vasodilation or vasoconstriction.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
08/21/2023
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Hypertension, Obesity
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Wild Blueberries and Cardiovascular Health in Middle-aged/Older Men and Postmenopausal Women
NCT04530916
Recruiting
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Aging is the primary risk factor for CVD, in large part due to adverse modifications to the arteries. These modifications include vascular endothelial dysfunction and arterial stiffness. Vascular endothelial dysfunction is an initiating step in atherosclerosis, and is primarily caused by reduced nitric oxide (NO) bioavailability secondary to excessive superoxide-driven oxidative stress and inflammation. Endot... Read More
Gender:
Male
Ages:
Between 45 years and 70 years
Trial Updated:
08/21/2023
Locations: Food and Nutrition Clinical Research Laboratory, Fort Collins, Colorado
Conditions: Hypertension, Aging, Endothelial Dysfunction, Men
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Enhancing Mental and Physical Health of Women Veterans
NCT05050266
Recruiting
Women Veterans are the fastest growing segment of VA users. This dramatic growth has created challenges for VA to ensure that appropriate services are available to meet women Veterans' needs, and that they will want and be able to use those services. The EMPOWER QUERI 2.0 Program is a cluster randomized type 3 hybrid implementation-effectiveness trial testing two strategies designed to support implementation and sustainment of evidence-based practices for women Veterans in up to 20 VA facilities... Read More
Gender:
All
Ages:
All
Trial Updated:
08/16/2023
Locations: VA Greater Los Angeles Healthcare System, West Los Angeles, CA, West Los Angeles, California
Conditions: Cardiovascular Diseases, Overweight, Obesity, Smoking, Hypertension, Cholesterol, Diabetes Mellitus, Prediabetic State, Pregnancy, Depression, Postpartum, Prevention, Implementation Science, Quality Improvement, Virtual Care
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BLOCKade of Calcium Channels and Beta Adrenergic Receptors for the Treatment of Hypertension in HFpEF
NCT04434664
Recruiting
Heart failure with preserved ejection fraction (HFpEF) is a critical public health problem. Heart failure (HF) affects over 5 million adults in the United States (US), and is a major source of morbidity, mortality, and impaired quality of life. Approximately half of individuals with HF have a preserved left ventricular (LV) ejection fraction (EF), termed HF with preserved EF (HFpEF). While there are several effective pharmacologic therapies for HF with reduced ejection fraction (HFrEF), none hav... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
08/16/2023
Locations: Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Heart Failure With Preserved Ejection Fraction, Hypertension
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Hypertension in Young Adults Trial
NCT05370599
Recruiting
This is a pilot randomized controlled trial which will test the effect of 3 different anti-hypertensive agents and 3 different strategies of engaging young adults in home blood pressure monitoring on blood pressure control, with secondary outcomes focused on quality of life and adverse events.
Gender:
All
Ages:
Between 18 years and 40 years
Trial Updated:
08/10/2023
Locations: University of California San Francisco, San Francisco, California
Conditions: Hypertension
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Engaging Native Hawaiian/Pacific Islanders and Activating Communities to Take Steps (ENACTS)
NCT03484364
Recruiting
Our Specific Aims are: At the individual level, to compare within-person change in BP and secondary outcomes between the intervention and control groups. At the family level, to evaluate ENACTS' effects on BP and secondary outcomes as within-person change in family members who provide primary support, and as mean change in other adult family members who are not directly engaged in the intervention. At the policy level, to evaluate the intervention's ability to influence grocery store policy on... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/10/2023
Locations: National Recruitment via Facebook and Internet, Seattle, Washington
Conditions: Hypertension
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Sleep and Circadian Mechanisms in Hypertension
NCT05184933
Recruiting
This study is a mechanistic clinical trial designed to investigate the effects of the circadian system and sleep on non-dipping blood pressure (BP) in people with hypertension (HTN).
Gender:
All
Ages:
Between 25 years and 64 years
Trial Updated:
08/07/2023
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Hypertension, Cardiovascular Diseases, Cardiovascular Risk Factors, Circadian Rhythms, Sleep
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