There are currently 163 active clinical trials seeking participants for Hypertension research studies. The states with the highest number of trials for Hypertension participants are California, Florida, Texas and Ontario.
Team-Based Home Blood Pressure Monitoring
NCT05488795
Recruiting
The overall goal of this study is to identify and rigorously evaluate strategies for implementing and sustaining team-based home blood pressure monitoring (TB-HBPM) within primary care. The TB-HBPM intervention is a multifaceted program involving patient transmission of blood readings to EHR and clinical decision support. Implementation strategies include group-based education on hypertension measurement, target blood pressure goals, drug and lifestyle management, referral to community resource... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
09/09/2024
Locations: Highland Family Medicine, Rochester, New York
Conditions: High Blood Pressure, Hypertension
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Improving Age-Related Cognitive Decline with Exercise in Hypertensive Older Adults
NCT05043454
Recruiting
The investigator aims to assess the extent to which a brief exercise intervention improves systemic growth factor concentrations, reverses loss of systemic vascular networks and hypertension, and by extension, improves neurocognition. To test the investigator's hypothesis that increased cardiovascular fitness will correlate with improved vascular density, the investigator proposes the innovative use of retinal density scans.
Gender:
ALL
Ages:
Between 55 years and 75 years
Trial Updated:
09/05/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Hypertension
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Study of Disrupted Sleep in Somali Americans
NCT05411029
Recruiting
The aims of this study are to determine the types and severity of previously undiagnosed sleep deficiencies in otherwise healthy Somali Americans, apply a research framework to define psychosocial, behavioral, environmental, and biological mechanisms mediating sleep deficiencies in Somali Americans, and examine the relationship between sleep deficiencies and increased blood pressure in Somali Americans.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
09/03/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Hypertension, Sleep Disorder, Healthy
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Peripheral Nerve Blocks for Above-the-knee Amputations
NCT03404180
Recruiting
Surgery performed with nerve blocks and sedation may be safer and provide better pain control compared to general anesthesia and opioid therapy in high-risk patient populations such as elderly and troubled with peripheral vascular disease, diabetes, hypertension, coronary artery disease, and chronic obstructive pulmonary disease (COPD).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/22/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Peripheral Vascular Diseases, Hyperglycaemia (Diabetic), Hypertension, Coronary Artery Disease, Pulmonary Disease, Chronic Obstructive
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VicorderCS NIBP Validation Study to Review The Ability to Capture Blood Pressure Measurements
NCT06560034
Recruiting
80 Beats Medical introduces the VicorderCS, the next generation of our Vicorder technology designed to manage hypertension and cardiovascular risks. This advanced diagnostic equipment offers non-invasive collection and computation of a plethora of cardiovascular markers. It is faster, easier to use, and more portable than its predecessor, with enhanced connectivity options for extended marker collection and analysis. These markers enable early diagnosis of cardiovascular disease, ensuring positi... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/15/2024
Locations: Manos Health Study Site, Breckenridge, Colorado
Conditions: Cardiovascular Diseases, Blood Pressure, Hypertension
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Ketone Ester and Acute Salt (KEAS) in Young Adults
NCT05545501
Recruiting
Most Americans consume excess dietary salt based on the recommendations set by the American Heart Association and Dietary Guidelines for Americans. High dietary salt impairs the ability of systemic blood vessels and the kidneys to control blood pressure, which contributes to excess salt consumption being associated with increased risk for chronic kidney disease and cardiovascular disease, the leading cause of death in America. There is a critical need for strategies to counteract the effects of... Read More
Gender:
ALL
Ages:
Between 18 years and 39 years
Trial Updated:
08/12/2024
Locations: Auburn University, Auburn, Alabama
Conditions: Salt; Excess, Hypertension
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Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)
NCT04838678
Recruiting
The purpose of this study is to understand how the nervous system communicates to blood vessels to increase blood pressure during stress. The study will also investigate how hypertension and obesity influence the nervous system and vascular function. The study will involve measuring sympathetic nervous system activity and blood flow during common laboratory physiological stress protocols (e.g. hypoxia, exercise), and in response to infusion of drugs that cause vasodilation or vasoconstriction.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
08/09/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Hypertension, Obesity
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Developing a Learning COmmunity to Increase eNgagemeNt and Enrollment in Cardiovascular Clinical Trials (CONNECT)
NCT06347484
Recruiting
The CONNECT: "Developing a learning COmmunity to increase eNgagemeNt and Enrollment in cardiovascular Clinical Trials" is comprehensive, participant-centered learning platform designed to increase diversity in cardiovascular disease research among women and Black and Latino adults. CONNECT will deploy electronic health record (EHR)-informed and community-engaged recruitment approaches to identify and recruit adults with cardiovascular disease or a cardiovascular disease risk factor to join CONNE... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/06/2024
Locations: Johns Hopkins University School of Nursing, Baltimore, Maryland
Conditions: Cardiovascular Diseases, Hypertension, Diabetes Type 2, Stroke, Recruitment, Overweight and Obesity, Hyperlipidemias
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MR Antagonist and LSD1
NCT04840342
Recruiting
Lysine specific demethylase-1 (LSD1) is an epigenetic regulator of gene transcription involved in the pathophysiology of elevated blood pressure and likely renal damage in Blacks. This project investigates whether a genetically driven anti-hypertensive approach proves superior in controlling blood pressure and mitigating renal injury in Blacks who carry the risk allele for LSD1 (rs587168). The findings of these investigations may lead to a new approach in treating a subset (\~30%) of the essenti... Read More
Gender:
ALL
Ages:
17 years and above
Trial Updated:
08/06/2024
Locations: Brigham and Women's, Boston, Massachusetts
Conditions: Hypertension, Mineralocorticoid Excess
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Wild Blueberries and Cardiovascular Health in Middle-aged/Older Men and Postmenopausal Women
NCT04530916
Recruiting
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Aging is the primary risk factor for CVD, in large part due to adverse modifications to the arteries. These modifications include vascular endothelial dysfunction and arterial stiffness. Vascular endothelial dysfunction is an initiating step in atherosclerosis, and is primarily caused by reduced nitric oxide (NO) bioavailability secondary to excessive superoxide-driven oxidative stress and inflammation. Endot... Read More
Gender:
MALE
Ages:
Between 45 years and 70 years
Trial Updated:
08/05/2024
Locations: Food and Nutrition Clinical Research Laboratory, Fort Collins, Colorado
Conditions: Hypertension, Aging, Endothelial Dysfunction, Men
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Comparison of Cuff-Less Wrist Wearable Blood Pressure Device to Cuff Based Blood Pressure Measuring Devices
NCT04835857
Recruiting
(1) To compare cuff-less wrist wearable radial artery blood pressure measurements utilizing ViTrack(developed by Dynocardia) to the cuff based commercially available blood pressure device, in healthy volunteers with normal or high blood pressure.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
08/05/2024
Locations: Dynocardia Inc, Newton, Massachusetts
Conditions: Hypertension, Healthy
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Reach Out 2: Emergency Department-Initiated Hypertension Mobile Health Intervention Connecting Multiple Health Systems
NCT06391073
Recruiting
Emergency department visits provide an opportunity to identify people with undiagnosed, untreated, or uncontrolled high blood pressure. In Reach Out, we will test whether a mobile health intervention yields a greater reduction in blood pressure than usual care among individuals identified with high blood pressure during a safety-net emergency department visit. Subsequently, we will estimate the reduction in heart attack, stroke, and dementia if Reach Out were implemented across all U.S. safety-n... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
08/02/2024
Locations: Hurley Medical Center, Flint, Michigan
Conditions: Hypertension
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