There are currently 158 active clinical trials seeking participants for Hypertension research studies. The states with the highest number of trials for Hypertension participants are California, Florida, Texas and Ontario.
A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities
NCT05321368
Recruiting
The LINKED- HEARTS Program is a multi-level project that intervenes at the practice level by linking home blood pressure monitoring (HBPM) with a telemonitoring platform (Sphygmo). The program incorporates team-based care by including community health workers (CHWs) and pharmacists to improve the outcomes of multiple chronic conditions (reduced blood pressure (BP), lower blood sugar, and improved kidney function). The LINKED-HEARTS Program will recruit a total of 600 adults with uncontrolled hyp... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/05/2025
Locations: Unity Health Care, Washington, District of Columbia +2 locations
Conditions: Hypertension, High Blood Pressure, Diabetes, Chronic Kidney Diseases
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Childhood-Onset Essential Hypertension Natural History Study
NCT06778239
Recruiting
Background: Childhood-onset essential hypertension (COEH) is high blood pressure that develops in children and teens. High blood pressure is a major risk factor for heart disease. COEH is more likely to be caused by changes in genes rather than by factors like stress or diet. Researchers want to learn more about how changes in genes relate to COEH. They hope to use that information to develop better treatments for children with high blood pressure. Objective: This natural history study will l... Read More
Gender:
ALL
Ages:
Between 2 years and 99 years
Trial Updated:
05/02/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Hypertension, Essential Hypertension
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Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks
NCT03374215
Recruiting
Background: The adrenal gland makes the hormone aldosterone. This helps regulate blood pressure. An adrenal gland tumor that makes too much aldosterone can cause high blood pressure and low potassium. The cause of these tumors is unknown, but sometimes they are inherited. Objective: To study the genes that may cause primary aldosteronism in Black individuals. Eligibility: People ages 18-70 who: Are Black, African American, or of Caribbean descent And have difficult to control blood pressu... Read More
Gender:
ALL
Ages:
Between 7 years and 70 years
Trial Updated:
05/02/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Adrenal Gland Neoplasm, Hypertension, Bone Diseases, Metabolic, Cardiovascular Disease, Hyperinsulinemia
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Diabetes and Heart Disease Risk in Blacks
NCT00001853
Recruiting
It is unknown if obesity contributes to the development of heart disease in African American men and women. This study was created to determine whether there is a relationship between sex and body size and the incidence of heart disease in African American men and women. Researchers will attempt to associate obesity with the presence of heart disease risk factors. Risk factors that will be studied include; total body fat, body fat distribution, fat content of the blood (triglyceride concentrati... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
05/02/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Diabetes, Obesity, Hypertension, Cardiovascular Diseases
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Food Insecurity, Social Determinants of Health
NCT06784310
Recruiting
Food is Medicine for the whole will test an intervention which provides medically tailored meals, or grocery voucher cards, or a combination of these food and nutrition resources to a caregiver and children living in the household. The study will examine how providing healthy tailored food and nutrition services can improve health outcomes, such as blood pressure and cholesterol levels.
Gender:
ALL
Ages:
Between 6 years and 64 years
Trial Updated:
05/01/2025
Locations: UofL Health, Louisville, Kentucky
Conditions: Food Insecurity, Type 2 Diabetes Mellitus (T2DM), Hypertension
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A Study to Investigate Tonlamarsen for the Treatment of Adults With Uncontrolled Hypertension
NCT06864104
Recruiting
The purpose of this study is to evaluate the blood pressure-lowering effect of tonlamarsen in adult participants who, despite taking 2 or more antihypertensive medications, have not achieved their target blood pressure (BP).
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/01/2025
Locations: Pinnacle Research Group, Anniston, Alabama +20 locations
Conditions: Hypertension
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Groceries Plus Multi-Component Lifestyle Intervention for Adults With Hypertension and Type 2 Diabetes
NCT06921356
Recruiting
People with high blood pressure and diabetes often have low levels of key nutrients as a result of not eating enough fresh fruits and vegetables. Research studies suggest that these nutrients can lower blood pressure and blood sugar. This study will investigate if providing encouragement to adopt this healthy and nutritious way of eating and providing guidance on weight management will lower blood pressure and blood sugar. The DASH-Life research study will recruit adults with hypertension and ty... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/01/2025
Locations: Johns Hopkins ProHealth Clinical Research Unit, Baltimore, Maryland
Conditions: Hypertension, Type 2 Diabetes Mellitus (T2DM)
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Conical Forearm and Cylindrical Upper Arm Non-Invasive Blood Pressure (NIBP) Measurements in Pregnant Patients
NCT06466161
Recruiting
The diagnosis of hypertensive disease during pregnancy is predicated on strict blood pressure thresholds: 140/90 on at least two occasions measured four hours apart for both gestational hypertension and preeclampsia. An improvement in diagnostic accuracy of even 5mm Hg would be significant, as reflected by the US Association for the Advancement of Medical Instrumentation (AAMI), the British Hypertension Society, the European Society of Hypertension (ESH) Working Group on Blood Pressure (BP) Moni... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/01/2025
Locations: Prentice Women's Hospital, Chicago, Illinois
Conditions: Hypertension in Pregnancy, Hypertension, Obesity
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Effect of Sublingually Generated S-nitroso-N-acetylcysteine on Systemic Blood Pressure.
NCT05798481
Recruiting
The purpose of the study is to increase the in vivo levels of nitric oxide by generating nitric oxide donor compound S-nitrosoacetylcysteine (SNOAC) using the mixture of sodium nitrite and N-acetylcysteine crystals in the sublingual space. The generated SNOAC rapidly diffuses into blood circulation thereby decrease the systemic blood pressure. This compound can be an alternative to organic nitrate NO donor drugs without developing tolerance in patients.
Gender:
ALL
Ages:
Between 21 years and 80 years
Trial Updated:
04/29/2025
Locations: Anesthesiology and Perioperative Medicine, Birmingham, Alabama
Conditions: Hypertension, Cardiovascular Diseases
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Implementation Strategies for Self-Measured Blood Pressure Monitoring in Racially and Ethnically Diverse Populations
NCT06871462
Recruiting
This clinical trial aims to assess the impact of patient-focused and clinical-focused implementation strategies on blood pressure control. The investigators will assess the costs of these strategies and how effective they were at safely and equitably increasing home blood pressure monitoring.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/29/2025
Locations: Zuckerberg San Francisco Hospital, San Francisco, California
Conditions: Blood Pressure Monitoring, Home, Hypertension
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Global Paradise System US Post Approval Study
NCT06297291
Recruiting
The objective of the Global Paradise® System US Post Approval Study (US GPS) is to evaluate the real-world use of the Paradise Ultrasound Renal Denervation System indicated for patients who are unable to lower their blood pressure with lifestyle changes and medication. This system is comprised of a catheter, cable, balloon, and generator and has received FDA approval in the United States. Information collected in this study will be analyzed to better understand the long-term safety and effective... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/29/2025
Locations: Sutter Institute for Medical Research, Sacramento, California +24 locations
Conditions: Hypertension, Cardiovascular Diseases, Vascular Diseases
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Inspiratory Muscle Strength Training in Chronic Kidney Disease
NCT04911491
Recruiting
More than 80% of individuals with chronic kidney disease have concomitant hypertension and the majority fail to achieve blood pressure control \<130/80 mmHg, leading to high risk of cardiovascular diseases and end-stage kidney disease. A stepwise combination of lifestyle modifications and drug therapy is recommended to lower blood pressure; however, adherence to time-intensive lifestyle interventions such as aerobic exercise in patients with chronic kidney disease is poor. This clinical trial se... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
04/29/2025
Locations: University of Colorado - Anschutz Medical Campus, Aurora, Colorado
Conditions: Chronic Kidney Diseases, Hypertension, Aging, Blood Pressure
Register for Updates