There are currently 162 active clinical trials seeking participants for Hypertension research studies. The states with the highest number of trials for Hypertension participants are California, Florida, Texas and Ontario.
Secondhand Tobacco Smoke and Cardiovascular Disease
NCT04715568
Recruiting
This is a double-blind randomized placebo-controlled crossover clinical trial of efficacy and safety of an FDA-approved angiotensin receptor blocker (losartan) to improve cardiopulmonary outcomes in individuals with pre-Chronic Obstructive Pulmonary Disease (COPD) due to prolonged exposure to secondhand tobacco smoke.
Gender:
All
Ages:
40 years and above
Trial Updated:
05/11/2023
Locations: San Francisco Veterans' Affairs Medical Center, San Francisco, California
Conditions: Cardiovascular Diseases, Hypertension
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Study 1: Effect of Minocycline Treatment on Drug-Resistant Hypertensive Patients
NCT02133872
Recruiting
Hypertension (HTN) is the single most prevalent risk factor for cardiovascular disease, diabetes, obesity and metabolic syndrome. Recent American Heart Association (AHA) statistics indicate that one-third of all adults in the United States of America suffer from HTN. Despite advances in life style modification and multi-drug therapies, 20-30% of all hypertensive patients remain resistant. These individuals exhibit autonomic dysregulation due to elevated sympathetic activity and norepinephrine s... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
05/08/2023
Locations: UF Health Cardiovascular Clinic, Gainesville, Florida
Conditions: Hypertension
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Telemonitoring Hypertension and Breast Cancer
NCT05574686
Recruiting
The goal of this clinical trial-prospective study will provide important information on equitable implementation strategies to improve hypertension management in women with breast cancer by evaluating the feasibility and safety of remote hypertension management using home blood pressure telemonitoring that will provide individualized hypertension management, health and wellness education for hypertension prevention of women with breast cancer stages I-IV. Also this study may provide evidence to... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/08/2023
Locations: University of Mississippi Medical Center Cancer Institute, Jackson, Mississippi
Conditions: Hypertension, Breast Cancer
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The PIVOT Trial: Project on EHR-Integrated Lifestyle Interventions for Adults Aged Fifty and Older
NCT05654142
Recruiting
This is a multisite clinical trial of healthy lifestyle programs for middle-to-older-aged adults (50 -74 years) to improve their weight and, therefore, reduce risk for chronic disease. This study will investigate whether a proven, self-directed video-based lifestyle program can be significantly enhanced with the assistance of a coach via videoconference or phone to help people as they adopt healthy eating and exercise behaviors. Additionally, the study will examine what factors might explain why... Read More
Gender:
All
Ages:
Between 50 years and 74 years
Trial Updated:
05/08/2023
Locations: Department of Medicine, Vitoux Program on Aging and Prevention, Chicago, Illinois +2 locations
Conditions: CARDIOMETABOLIC CONDITIONS, Obesity, Pre-diabetes, Metabolic Syndrome, Type2diabetes, Hypertension, Dyslipidemias
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Vitamin D and Immune Mechanisms of Hypertension in Type 2 Diabetics
NCT03348280
Recruiting
This trial will evaluate whether a particular type of circulating white blood cell, monocytes, from type 2 diabetics with high blood pressure and vitamin D deficiency vs. sufficiency will induce hormones that increase blood pressure.
Gender:
All
Ages:
Between 25 years and 80 years
Trial Updated:
04/21/2023
Locations: Barnes-Jewish & Washington University Diabetes Center, Saint Louis, Missouri +1 locations
Conditions: Diabetes Mellitus, Type 2, Hypertension, Vitamin D Deficiency
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Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study
NCT05030545
Recruiting
This research study aims to learn more about the impact the hormone aldosterone on the heart. Primary aldosteronism is a condition where the body's adrenal glands make too much of the hormone aldosterone, which can cause high blood pressure and increase the risk of heart and kidney disease. Treatment with medications that block aldosterone can reduce that risk. This study is trying to learn whether treatment with a medication that blocks aldosterone can improve heart function in people who make... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
02/24/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Primary Aldosteronism, Hypertension
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The Path to Optimal Black Maternal Heart Health: Comparing Two CVD Risk Reduction Interventions (Change of HEART)
NCT05499507
Recruiting
The overarching goal of our proposal is to reduce disparities in perinatal cardiovascular disease risk factors among Black women utilizing a community-driven, social ecological framework.
Gender:
Female
Ages:
18 years and above
Trial Updated:
02/21/2023
Locations: Temple University/Temple Health, Philadelphia, Pennsylvania
Conditions: Pregnancy Related, Hypertension, Obesity, Racism
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Mi Propio Camino Intervention RCT for Blood Pressure Medication Adherence
NCT04585594
Recruiting
The purpose of this study is to compare the effect of two educational interventions on adherence to blood pressure medications among adults with uncontrolled hypertension.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/03/2023
Locations: Health Policy Research Institute, Irvine, California
Conditions: Hypertension, Medication Adherence
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Chymase Angiotensin-(1-12) Axis In Hypertensive Disease
NCT05644769
Recruiting
Determine the presence of the human sequence of Angiotensin-(1-12) in plasma of ten untreated hypertensive subjects and after 4 week with Lisinopril 40 mg every day. Determine the blood pressure reduction with Lisinopril 40mg.
Gender:
All
Ages:
Between 40 years and 75 years
Trial Updated:
12/06/2022
Locations: Punzi Medical Center, Carrollton, Texas
Conditions: Hypertension
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Dietary Sodium Intake and Blood Pressure in Living Kidney Donors
NCT05041829
Recruiting
This is a pilot study to determine the feasibility of the study design and examine the main outcome whether low dietary sodium intake is superior to high dietary sodium intake in controlling blood pressure to be within the normotensive range in living kidney donors.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/30/2022
Locations: University of California Irvine Medical Center, Orange, California
Conditions: Hypertension, Living Kidney Donor, Dietary Sodium Intake
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Improving Blood Pressure and Cardiovascular Risk With Resistance Exercise in African Americans
NCT03016351
Recruiting
After the participant meets all inclusion and exclusion criteria, they will be randomized equally to either the Resistance Training group (RT) or Aerobic Training group (AT). Both groups will participate in an 8 week initial control period, followed by 8 weeks of supervised exercise training, followed by 8 weeks of deconditioning. All participants will undergo the same assessments and procedures one time prior to the initial 8 week control period, and at each of the three periods. Assessments in... Read More
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
10/31/2022
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Hypertension, Cardiovascular Diseases, Vascular Diseases
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Renal Metabolism in Salt-sensitive Human Blood Pressure
NCT05369416
Recruiting
Salt sensitive hypertension is a significant health problem worldwide and a primary modifiable risk factor for renal, cardiovascular, and cerebrovascular diseases. Yet, the underlying mechanisms remain poorly understood. The proposed study determines how renal oxygenation and substrate metabolism differs between individuals with and without salt sensitivity, with the ultimate goal of identifying mechanisms, diagnostic criteria, and treatment strategies for salt sensitive hypertension.
Gender:
All
Ages:
Between 30 years and 65 years
Trial Updated:
05/23/2022
Locations: Medical College of Wisconsin /Froedtert Hospital, Milwaukee, Wisconsin
Conditions: Hypertension
Register for Updates