There are currently 167 active clinical trials seeking participants for Hypertension research studies. The states with the highest number of trials for Autism participants are California, Florida, Texas and Ontario.
Ketone Ester and Acute Salt (KEAS) in Young Adults
Recruiting
Most Americans consume excess dietary salt based on the recommendations set by the American Heart Association and Dietary Guidelines for Americans. High dietary salt impairs the ability of systemic blood vessels and the kidneys to control blood pressure, which contributes to excess salt consumption being associated with increased risk for chronic kidney disease and cardiovascular disease, the leading cause of death in America. There is a critical need for strategies to counteract the effects of... Read More
Gender:
All
Ages:
Between 18 years and 39 years
Trial Updated:
05/30/2023
Locations: Auburn University, Auburn, Alabama
Conditions: Salt; Excess, Hypertension
Storytelling Intervention for African Americans Living With Hypertension
Recruiting
Narrative communication (e.g., storytelling) is an approach that has contributed to behavioral change for individuals with conditions such as diabetes, breast cancer, and hypertension. The objective of this study is to conduct a feasibility and pilot study storytelling intervention for African Americans with hypertension. In the feasibility phase 30 African Americans with hypertension will be recruited to view nine patient stories and provide feedback on the effectiveness, usefulness, and satisf... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/30/2023
Locations: University of Delaware, Newark, Delaware
Conditions: Hypertension
Implementation of Multifaceted Patient-Centered Treatment Strategies for Intensive Blood Pressure Control in Minimize Cognitive Decline
Recruiting
The proposed study will test a multifaceted strategy for implementing an intensive blood pressure intervention protocol targeting systolic BP <120 mmHg on cognitive decline in racial minority and low-income hypertensive patients in primary care. The proposed study will generate urgently needed data on effective, adoptable, and equitable intervention strategies to reduce blood pressure-related cognitive decline in low- income and minority populations. If proven effective, the implementation strat... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
05/15/2023
Locations: Tulane University, New Orleans, Louisiana
Conditions: Hypertension, Cognitive Decline
Secondhand Tobacco Smoke and Cardiovascular Disease
Recruiting
This is a double-blind randomized placebo-controlled crossover clinical trial of efficacy and safety of an FDA-approved angiotensin receptor blocker (losartan) to improve cardiopulmonary outcomes in individuals with pre-Chronic Obstructive Pulmonary Disease (COPD) due to prolonged exposure to secondhand tobacco smoke.
Gender:
All
Ages:
40 years and above
Trial Updated:
05/11/2023
Locations: San Francisco Veterans' Affairs Medical Center, San Francisco, California
Conditions: Cardiovascular Diseases, Hypertension
Telemonitoring Hypertension and Breast Cancer
Recruiting
The goal of this clinical trial-prospective study will provide important information on equitable implementation strategies to improve hypertension management in women with breast cancer by evaluating the feasibility and safety of remote hypertension management using home blood pressure telemonitoring that will provide individualized hypertension management, health and wellness education for hypertension prevention of women with breast cancer stages I-IV. Also this study may provide evidence to... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/08/2023
Locations: University of Mississippi Medical Center Cancer Institute, Jackson, Mississippi
Conditions: Hypertension, Breast Cancer
Study 1: Effect of Minocycline Treatment on Drug-Resistant Hypertensive Patients
Recruiting
Hypertension (HTN) is the single most prevalent risk factor for cardiovascular disease, diabetes, obesity and metabolic syndrome. Recent American Heart Association (AHA) statistics indicate that one-third of all adults in the United States of America suffer from HTN. Despite advances in life style modification and multi-drug therapies, 20-30% of all hypertensive patients remain resistant. These individuals exhibit autonomic dysregulation due to elevated sympathetic activity and norepinephrine s... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
05/08/2023
Locations: UF Health Cardiovascular Clinic, Gainesville, Florida
Conditions: Hypertension
The PIVOT Trial: Project on EHR-Integrated Lifestyle Interventions for Adults Aged Fifty and Older
Recruiting
This is a multisite clinical trial of healthy lifestyle programs for middle-to-older-aged adults (50 -74 years) to improve their weight and, therefore, reduce risk for chronic disease. This study will investigate whether a proven, self-directed video-based lifestyle program can be significantly enhanced with the assistance of a coach via videoconference or phone to help people as they adopt healthy eating and exercise behaviors. Additionally, the study will examine what factors might explain why... Read More
Gender:
All
Ages:
Between 50 years and 74 years
Trial Updated:
05/08/2023
Locations: Department of Medicine, Vitoux Program on Aging and Prevention, Chicago, Illinois +2 locations
Conditions: CARDIOMETABOLIC CONDITIONS, Obesity, Pre-diabetes, Metabolic Syndrome, Type2diabetes, Hypertension, Dyslipidemias
Vitamin D and Immune Mechanisms of Hypertension in Type 2 Diabetics
Recruiting
This trial will evaluate whether a particular type of circulating white blood cell, monocytes, from type 2 diabetics with high blood pressure and vitamin D deficiency vs. sufficiency will induce hormones that increase blood pressure.
Gender:
All
Ages:
Between 25 years and 80 years
Trial Updated:
04/21/2023
Locations: Barnes-Jewish & Washington University Diabetes Center, Saint Louis, Missouri +1 locations
Conditions: Diabetes Mellitus, Type 2, Hypertension, Vitamin D Deficiency
Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study
Recruiting
This research study aims to learn more about the impact the hormone aldosterone on the heart. Primary aldosteronism is a condition where the body's adrenal glands make too much of the hormone aldosterone, which can cause high blood pressure and increase the risk of heart and kidney disease. Treatment with medications that block aldosterone can reduce that risk. This study is trying to learn whether treatment with a medication that blocks aldosterone can improve heart function in people who make... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
02/24/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Primary Aldosteronism, Hypertension
The Path to Optimal Black Maternal Heart Health: Comparing Two CVD Risk Reduction Interventions (Change of HEART)
Recruiting
The overarching goal of our proposal is to reduce disparities in perinatal cardiovascular disease risk factors among Black women utilizing a community-driven, social ecological framework.
Gender:
Female
Ages:
18 years and above
Trial Updated:
02/21/2023
Locations: Temple University/Temple Health, Philadelphia, Pennsylvania
Conditions: Pregnancy Related, Hypertension, Obesity, Racism
Mi Propio Camino Intervention RCT for Blood Pressure Medication Adherence
Recruiting
The purpose of this study is to compare the effect of two educational interventions on adherence to blood pressure medications among adults with uncontrolled hypertension.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/03/2023
Locations: Health Policy Research Institute, Irvine, California
Conditions: Hypertension, Medication Adherence
Improving Hypertension Medication Adherence for Older Adults
Recruiting
This randomized controlled trial will assess the efficacy and scalability of a blood pressure technology system intervention. The investigators will enroll 224 older adults with hypertension to identify those who are nonadherent for one hypertension medication. The participants will be randomized to one of two groups (112 per group) to use the blood pressure system for 6-months. Both groups receive information about high blood pressure and medications. One group will also receive strategies that... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
01/26/2023
Locations: University of Arizona, Tucson, Arizona +1 locations
Conditions: Aging, Medication Adherence, Hypertension