There are currently 167 active clinical trials seeking participants for Hypertension research studies. The states with the highest number of trials for Autism participants are California, Florida, Texas and Ontario.
A Pivotal Study to Evaluate the Efficacy of Lorundrostat in Subjects With Uncontrolled Hypertension on a Standardized Antihypertensive Medication Regimen
NCT05769608
Recruiting
a Phase 2 trial to evaluate the blood pressure-lowering effect of lorundrostat (an aldosterone synthase inhibitor), administered on a background of a standardized anti-hypertensive (AHT) medication regimen, in subjects with uncontrolled and/or treatment-resistant hypertension.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/24/2024
Locations: Cardiology, P.C. - Birmingham, Birmingham, Alabama +90 locations
Conditions: Hypertension
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Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
NCT06374277
Recruiting
Socioeconomically disadvantaged populations with multiple chronic conditions have high rates of nonadherence to essential chronic disease medications after hospital discharge. Medication nonadherence after hospital discharge is significantly associated with increased mortality and higher rates of readmissions and costs among these patients. Major patient-reported barriers to essential medication use after hospital discharge among low-income individuals are related to social determinants of healt... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: University of Tennessee Medical Center, Knoxville, Tennessee +1 locations
Conditions: Diabetes, Hypertension, High Cholesterol/Hyperlipidemia, Coronary Artery Disease, Congestive Heart Failure, Chronic Lung Disease, Chronic Kidney Diseases, Arrythmia, Stroke, Depression, Anxiety, Pulmonary Embolism, Heart Attack
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Community Mobilization for Improved Clean Cookstove Uptake, Household Air Pollution Reduction, and Hypertension Prevention
NCT05048147
Recruiting
Using a focused implementation research framework, the EPIS (Exploration, Preparation, Implementation and Sustainment) model in a type-2 hybrid design, the study will be conducted in 3 phases: 1) A pre-implementation phase that will use the Exploration and Preparation domains of EPIS to: a) explore barriers and facilitators of Clean Fuel- Clean- Stove (CF-CS) use, and b) develop a culturally-tailored CM strategy for CF-CS use; 2) An Implementation phase that will use the Implementation domain of... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
04/23/2024
Locations: University of Chicago, Chicago, Illinois +1 locations
Conditions: Hypertension
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Home Blood Pressure Telemonitoring LINKED With Community Health Workers to Improve Blood Pressure
NCT05180045
Recruiting
The LINKED-BP Program is a patient-centered, multi-level intervention linking home blood pressure monitoring (HBPM) with a telemonitoring platform (Sphygmo) that links with all Bluetooth-enabled validated blood pressure (BP) devices, support from community health workers (CHWs), and BP measurement training at community health centers serving high-risk adults to prevent stage 2 hypertension (BP ≥ 140/90 mm Hg). The LINKED-BP Program study will recruit a total of 600 adults (30 from each practice)... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/18/2024
Locations: Johns Hopkins Community Physicians Remington, Baltimore, Maryland +9 locations
Conditions: Hypertension, High Blood Pressure
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Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications (KARDIA-3)
NCT06272487
Recruiting
The purpose of this study is to evaluate the effect of zilebesiran as add-on therapy in patients with high cardiovascular risk and hypertension not adequately controlled by standard of care antihypertensive medications.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: Clinical Trial Site, Flint, Michigan
Conditions: High Cardiovascular Risk, Hypertension
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A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients
NCT03626688
Recruiting
Study ROR-PH-301, ADVANCE OUTCOMES, is designed to assess the efficacy and safety of ralinepag when added to pulmonary arterial hypertension (PAH) standard of care or PAH-specific background therapy in subjects with World Health Organization (WHO) Group 1 PAH.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +212 locations
Conditions: PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension, Connective Tissue Diseases, Familial Primary Pulmonary Hypertension, Vascular Diseases, Cardiovascular Diseases, Hypertension, Pulmonary, Lung Diseases, Respiratory Tract Disease
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Examining Digital Health Care Delivery Models Through Medicaid Collaborative
NCT05555095
Recruiting
The purpose of this study is to examine the intervention effectiveness and dissemination of digital health care delivery models for improving selected health outcomes in the Medicaid population.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: OSF HealthCare System, Peoria, Illinois
Conditions: Hypertension, Diabetes Mellitus, Maternal Health
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Improving Blood Pressure Control in Stroke Patients by Increasing Access to a Home Blood Pressure Monitor
NCT05730465
Recruiting
The goal of this clinical trial is to learn whether providing teaching with a low-cost device can help to improve blood pressure, health outcomes, patient self-efficacy without exacerbating inequity between advantaged and disadvantaged patients. The main question[s] it aims to answer are: Does providing a free home blood pressure cuff improve control of hypertension? Does providing a free home blood pressure cuff have a greater impact on control of hypertension in disadvantaged populations? Do... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/16/2024
Locations: Stanford University Hospital, Palo Alto, California
Conditions: Hypertension, Stroke, TIA, Vascular Diseases
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Therapeutic Mechanisms of Epidural Spinal Cord Stimulation
NCT05556902
Recruiting
The purpose of this study in patients undergoing routine care epidural spinal cord stimulation (SCS) is to determine 1) whether SCS reduces arterial blood pressure (BP) in patients which chronic low back pain and hypertension, 2) whether higher baseline BP (i.e., hypertension) predicts reductions in pain following SCS, and finally 3) whether different SCS waveforms elicits stimulus-evoked compound action potentials (ECAPs) in spinal cord and at the cortex (electroencephalography, and magnetoench... Read More
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
04/12/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Blood Pressure, Low Back Pain, Hypertension
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Autonomic Regulation of Blood Pressure in Premature and Early Menopausal Women
NCT04439370
Recruiting
This is a cross-sectional study in which the investigators will determine the impact of premature/early menopause on MSNA, BP and baroreflex sensitivity in younger (≤49 yr old) and older (≥50 yr old) women. Specifically, aim one will determine mechanisms driving autonomic dysregulation of BP in premature and early menopausal women and aim two will determine mechanisms driving autonomic dysregulation of BP in older menopausal women. The study design outlined below will permit testing of aim one a... Read More
Gender:
Female
Ages:
Between 35 years and 70 years
Trial Updated:
04/12/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Hypertension, Menopause, Premature, Menopause, Blood Pressure
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Medication Adherence Program
NCT05183763
Recruiting
Randomized controlled trial testing the efficacy of the Supporting Tailored Adaptive change and Reinforcement for Medication Adherence Program (STAR-MAP), a health coaching approach that aims to improve antihypertensive medication adherence, blood pressure control, and quality of life. Participants (n=402) >=50 years old with a diagnosis of hypertension, uncontrolled blood pressure, and low antihypertensive medication adherence will be recruited through a statewide health insurer, Blue Cross Blu... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
04/11/2024
Locations: Pennington Biomedical Research Center, Baton Rouge, Louisiana +4 locations
Conditions: Hypertension, Medication Adherence, Behavior and Behavior Mechanisms
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SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
NCT05198674
Recruiting
The purpose of this single-arm interventional study is to evaluate the long-term safety, efficacy, and durability of the Symplicity Spyral system in subjects treated with renal denervation. Additionally, long-term follow-up data will also be collected from eligible subjects previously treated in the SPYRAL PIVOTAL-SPYRAL HTN-OFF MED and SPYRAL HTN-ON MED studies.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/11/2024
Locations: University of Alabama at Birmingham (UAB) Hospital, Birmingham, Alabama +79 locations
Conditions: Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
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