There are currently 162 active clinical trials seeking participants for Hypertension research studies. The states with the highest number of trials for Hypertension participants are California, Florida, Texas and Ontario.
A Pivotal Study to Evaluate the Efficacy of Lorundrostat in Subjects With Uncontrolled Hypertension on a Standardized Antihypertensive Medication Regimen
NCT05769608
Recruiting
a Phase 2 trial to evaluate the blood pressure-lowering effect of lorundrostat (an aldosterone synthase inhibitor), administered on a background of a standardized anti-hypertensive (AHT) medication regimen, in subjects with uncontrolled and/or treatment-resistant hypertension.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/11/2024
Locations: Cardiology, P.C. - Birmingham, Birmingham, Alabama +100 locations
Conditions: Hypertension
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Exercise and Vascular Function in Postmenopausal Females With Hypertension
NCT05597033
Recruiting
The treatment of high blood pressure, or hypertension, is multifaceted and can include pharmacological therapies (i.e., medications) and lifestyle modifications such as physical activity. Chronotherapy, which describes timing of a treatment with the body's daily rhythms, has recently been used with hypertension medications and has been shown to be effective at lowering blood pressure and reducing the risk of cardiovascular disease events. Specifically, taking medications in the evening was shown... Read More
Gender:
Female
Ages:
Between 55 years and 80 years
Trial Updated:
06/11/2024
Locations: Michigan State University, East Lansing, Michigan
Conditions: Hypertension
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Treatment With Aspirin After Preeclampsia: TAP Trial
NCT06281665
Recruiting
The objective of this research project is to conduct a single-site pilot trial to assess the feasibility and effect of low-dose aspirin to augment vascular recovery in the immediate postpartum period after preeclampsia through two specific aims: 1) to pilot test the feasibility of conducting a randomized controlled trial of postpartum low dose aspirin vs. placebo, and 2) to assess the effect of postpartum aspirin on endothelial function and blood pressure. Our central hypothesis is that postpart... Read More
Gender:
Female
Ages:
Between 18 years and 55 years
Trial Updated:
06/11/2024
Locations: University of Pittsburgh Magee-Womens Hospital, Pittsburgh, Pennsylvania
Conditions: Hypertensive Disorder of Pregnancy, Pre-Eclampsia, Hypertension, Eclampsia, Gestational Hypertension, Cardiovascular Diseases, Toxemia, Pregnancy Complications, Vascular Diseases, Hypertension, Pregnancy Induced, Hypertension;Pre-Eclamptic
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AM vs PM Exercise Training
NCT06042439
Recruiting
The treatment of high blood pressure, or hypertension, is multifaceted and can include pharmacological therapies (i.e., medications) and lifestyle modifications such as physical activity. Chronotherapy, which describes timing of a treatment with the body's daily rhythms, has recently been used with hypertension medications and has been shown to be effective at lowering blood pressure and reducing the risk of cardiovascular disease events. Specifically, taking medications in the evening was shown... Read More
Gender:
Female
Ages:
Between 55 years and 80 years
Trial Updated:
06/11/2024
Locations: Michigan State University, East Lansing, Michigan
Conditions: Hypertension
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The Impact of KETO5 XOGenius Beverage on Markers of Physiological and Neurocognitive Health
NCT06318390
Recruiting
The primary objectives of this application are to 1) investigate the effect of increased daily consumption of the Keto5 XOGenius beverage on outcomes associated with elevated risk for various neurocognitive and pathophysiological conditions/diseases. And 2) to investigate the effect of daily consumption of the Keto5 XOGenius beverage on the following variables: waist circumference, body weight, and body mass index (BMI).
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
06/10/2024
Locations: UT Arlington - Science and Engineering Innovation and Research Building, Arlington, Texas
Conditions: Cardiovascular Diseases, Hypertension, Cognitive Decline, Diet, Healthy
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Open-Label Extension Study to Assess Safety, Efficacy, and Tolerability of Lorundrostat in Subjects With Uncontrolled Hypertension
NCT05968430
Recruiting
This study is to evaluate the long-term safety, efficacy and tolerability of lorundrostat (an aldosterone synthase inhibitor) in subjects with uncontrolled hypertension.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/10/2024
Locations: Accel Research Sites (ARS) - Birmingham Clinical Research Unit, Birmingham, Alabama +40 locations
Conditions: Hypertension
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The Acute Effect of and Energy Drink vs. Water Consumption on MAP, HR, and Energy Metabolism
NCT06330649
Recruiting
The objective of this protocol is to investigate the effect of consumption of a commercially available energy drink beverage on blood pressure, heart rate, and energy metabolism
Gender:
All
Ages:
Between 18 years and 30 years
Trial Updated:
06/10/2024
Locations: UT Arlington - Science and Engineering Innovation and Research Building, Arlington, Texas
Conditions: Cardiovascular Diseases, Hypertension, Diet
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Contributions to Hypertension With Androgen Deprivation Therapy
NCT05700903
Recruiting
This study plans to learn more about contributors to high blood pressure in men who undergo androgen deprivation therapy (ADT) to treat prostate cancer. Prostate cancer is the most common non-skin cancer in men, affecting approximately 1 in 8 American men and its primary treatment is through the use of ADT. However, ADT increases the likelihood of developing heart disease including high blood pressure. This study will determine if dysfunction of the nervous system and/or kidneys occurs in men un... Read More
Gender:
Male
Ages:
40 years and above
Trial Updated:
06/10/2024
Locations: UCHealth University of Colorado Hospital, Aurora, Colorado
Conditions: Androgen Deprivation Therapy, Prostate Cancer, Hypertension, Autonomic Dysfunction, Renal Disease
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Peanuts and Neurocognitive / Cardiovascular Health in Black Individuals
NCT06318377
Recruiting
The overall research objective of this proposal is to determine the impact of increased daily peanut consumption on indices of neurocognitive and physiological health in BL individuals
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
06/10/2024
Locations: UT Arlington - Science and Engineering Innovation and Research Building, Arlington, Texas
Conditions: Cardiovascular Diseases, Hypertension, Cognitive Decline, Diet, Healthy
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SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
NCT05198674
Recruiting
The purpose of this single-arm interventional study is to evaluate the long-term safety, efficacy, and durability of the Symplicity Spyral system in subjects treated with renal denervation. Additionally, long-term follow-up data will also be collected from eligible subjects previously treated in the SPYRAL PIVOTAL-SPYRAL HTN-OFF MED and SPYRAL HTN-ON MED studies.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/07/2024
Locations: University of Alabama at Birmingham (UAB) Hospital, Birmingham, Alabama +83 locations
Conditions: Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
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Equity in Prevention and Progression of Hypertension by Addressing Barriers to Nutrition and Physical activitY
NCT05367544
Recruiting
The goal of this study is to test an intervention to prevent high blood pressure among rural, Black adults living in Alabama. Black adults in this region have one of the highest rates of high blood pressure in the US. Eating fruits and vegetables and exercising daily lowers the chance of getting high blood pressure. Many problems get in the way of eating a healthy diet and exercising like a lack of grocery stores with fresh foods, few gyms, little money, lack of transportation, and limited suppo... Read More
Gender:
All
Ages:
19 years and above
Trial Updated:
06/07/2024
Locations: University of Alabama At Birmingham, Birmingham, Alabama
Conditions: Prehypertension, Hypertension, Blood Pressure
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AdapTive Personalized Dietitian coacHing, Messaging and pRoduce prescrIption to improVE Healthy Dietary Behaviors
NCT06257550
Recruiting
THRIVE intervention is a 2-arm randomized pilot trial testing the feasibility and preliminary efficacy of producing prescriptions, tailored dietitian counseling with adaptive messages, and linkages to social resources among 60 Black adults with hypertension.
Gender:
All
Ages:
Between 18 years and 79 years
Trial Updated:
06/04/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Hypertension
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