There are currently 165 active clinical trials seeking participants for Hypertension research studies. The states with the highest number of trials for Hypertension participants are California, Florida, Texas and Ontario.
Biological Sample Repository for Gastrointestinal Disorders
Recruiting
The goal of this observational study has the purpose of collecting biological samples from obese patients undergoing evaluation for weight loss by means of medical or endoscopic therapies; and of post bariatric surgery patients presenting with short- and long-term surgical complications. The aim is to enhance the overall understanding of the mechanisms leading to obesity, weight loss, failure to lose weight, and weight regain following treatment. Additional goals are to determine the efficacy of... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/04/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder, Overweight and Obesity, Overweight, Overweight or Obesity, Diabetes Type 2, Diabetes Mellitus, Diabetes Mellitus, Type 2, Hypertension, Hyperlipidemias, Sleep Apnea, GERD, Gastroesophageal Reflux, Musculoskeletal Pain Disorder, Cancer
HELP-HY: Health Education and sLeep Program in HYpertension
Recruiting
Hypertension is the major risk factor for cardiovascular and cerebrovascular diseases worldwide. The escalating prevalence of inadequate sleep now parallels that of hypertension. Observational and experimental evidence favoring a causal relation between insufficient sleep and hypertension are particularly compelling - sleeping 6 hours or less per night is associated with a 20-32% higher probability of incident hypertension. Since sleep curtailment is largely voluntary, sleep deficiency may be co... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
08/02/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Prehypertension, Hypertension
Remote Monitoring and Virtual Collaborative Care For Hypertension Control to Prevent Cognitive Decline Phase II
Recruiting
This is a randomized, controlled, pragmatic trial designed as a "type I hybrid effectiveness-implementation trial" that tests a hypertension program integrating a virtual Collaborative Care Clinic (vCCC), home blood pressure monitoring, and telehealth for lowering blood pressure (BP) in two health systems.
Gender:
All
Ages:
65 years and above
Trial Updated:
08/01/2023
Locations: University of Kansas Health System, Kansas City, Kansas +1 locations
Conditions: Hypertension
Health Disparities in Prevalence of Hypertension Between Black and White Americans
Recruiting
This study will be the first to distinguish the relative contributions of sleep, circadian and behavioral mechanisms to the non-dipping BP profile in Black adults and will lay the groundwork for optimizing therapies dependent on mechanisms, such as targeting sleep, targeting circadian rhythmicity, or targeting behaviors, and raising the possibility that ideal therapy for hypertension (HTN) may differ by race. This research will ultimately help to improve health and survival in black populations... Read More
Gender:
All
Ages:
Between 40 years and 60 years
Trial Updated:
07/31/2023
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Hypertension, Cardiovascular Risk Factor
MR Antagonist and LSD1
Recruiting
Lysine specific demethylase-1 (LSD1) is an epigenetic regulator of gene transcription involved in the pathophysiology of elevated blood pressure and likely renal damage in Blacks. This project investigates whether a genetically driven anti-hypertensive approach proves superior in controlling blood pressure and mitigating renal injury in Blacks who carry the risk allele for LSD1 (rs587168). The findings of these investigations may lead to a new approach in treating a subset (~30%) of the essentia... Read More
Gender:
All
Ages:
17 years and above
Trial Updated:
07/27/2023
Locations: Brigham and Women's, Boston, Massachusetts
Conditions: Hypertension, Mineralocorticoid Excess
Team-Based Home Blood Pressure Monitoring
Recruiting
The overall goal of this study is to identify and rigorously evaluate strategies for implementing and sustaining team-based home blood pressure monitoring (TB-HBPM) within primary care. The TB-HBPM intervention is a multifaceted program involving patient transmission of blood readings to EHR and clinical decision support. Implementation strategies include group-based education on hypertension measurement, target blood pressure goals, drug and lifestyle management, referral to community resource... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
07/20/2023
Locations: Highland Family Medicine, Rochester, New York
Conditions: High Blood Pressure, Hypertension
Habitual Hypertension Medication Adherence in Arizona
Recruiting
This research will implement a novel habit formation intervention among people living with hypertension and an indication of medication non-adherence to help maintain high anti-hypertensive (AH) medication adherence by leveraging the power of routines and unconsciously triggered habitual behaviors. The investigators will test whether high AH medication adherence can be maintained using contextually-cued medication adherence habits that mitigate the negative effects of declining motivation, forge... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/19/2023
Locations: Arizona State University, Phoenix, Arizona
Conditions: Medication Adherence, Habits, Hypertension
Addressing Barriers to Achieving Cardiometabolic Disorders Prevention and Treatment Goals for PLWH in the SE US
Recruiting
This study has 3 aims. Aim 1: Identify social determinants of cardiometabolic health and determine facilitators and modifiable barriers in achieving treatment goals. Aim 2: Assess PLWH knowledge, skills, and confidence for self-management of cardiometabolic disorders. Aim 3: Tailor a self-management support and education intervention with stakeholder input to address barriers to achieving treatment goals for cardiometabolic disorders in PLWH at the study sites.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/11/2023
Locations: Duke University - Charlotte Study Sites, Charlotte, North Carolina +1 locations
Conditions: Hypertension, Dyslipidemias, Type 2 Diabetes, HIV-1-infection
Addressing Barriers to Anti-hypertensive Medication Adherence Among PLWH Who Have Achieved Viral Suppression
Recruiting
Among those with hypertension, persons living with HIV (PWH) have a 50% higher risk of incident myocardial infarction compared to the general population, and they often fail to meet evidence-based treatment goals for hypertension. An important contributing factor for insufficient blood pressure control is non-adherence to antihypertensive medications. Research on medication adherence for PWH has largely focused on antiretroviral therapy adherence with limited focus on adherence to other non-AIDS... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/11/2023
Locations: Duke University, Durham, North Carolina
Conditions: Hypertension, HIV-1-infection
Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial
Recruiting
This is a single site, single-blinded parallel randomized control trial that investigates a multi-level intervention to improve postpartum blood pressure in women with hypertensive disorder pregnancy. The investigators will recruit women diagnosed with a hypertensive disorder of pregnancy, identified between 3rd trimester and 2 weeks post-delivery. The investigators will randomize participants to receive usual care home blood pressure monitoring for 6 weeks versus an intervention of usual care +... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/05/2023
Locations: Magee Women's Hospital of UPMC, Pittsburgh, Pennsylvania
Conditions: Preeclampsia, Hypertensive Disorder of Pregnancy, Toxemia, Pregnancy Complications, Hypertension, Pregnancy-Induced, Hypertension, Obesity, Overweight, Nutrition Disorders, Vascular Diseases, Cardiovascular Diseases, Pre-Eclampsia, Eclampsia, Gestational Hypertension
Breathing Training for Improving Cardiovascular Health in Older Adults With Sleep Apnea
Recruiting
This clinical research study will investigate the effects of respiratory strength training on blood pressure and cardiovascular health in adults who are 50 years of age and older and have been diagnosed with moderate or severe obstructive sleep apnea.
Gender:
All
Ages:
50 years and above
Trial Updated:
06/30/2023
Locations: Arizona Respiratory and Neurophysiology Laboratory, Tucson, Arizona
Conditions: Obstructive Sleep Apnea, Hypertension
Effect of Electro-Acupuncture on Blood Pressure
Recruiting
Based on previous published research in animals and human, the investigators hypothesize that electroacupuncture (EA) will have a positive effect on hypertension.
Gender:
All
Ages:
Between 39 years and 85 years
Trial Updated:
06/15/2023
Locations: Susan Samueli Integrative Health Institute, Costa Mesa, California +1 locations
Conditions: Hypertension