There are currently 163 active clinical trials seeking participants for Hypertension research studies. The states with the highest number of trials for Hypertension participants are California, Florida, Texas and Ontario.
Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure
NCT06507657
Recruiting
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce CVD events, including incident HF. SGLT2 is a glucose transport protein in the kidneys. Inhibition of this protein results in glucosuria and lower serum blood sugar. The SGLT2i medications were initially approved to treat type 2 diabetes (T2D). In 2015, Zinman et al. published the first large randomized clinical trial (RCT) demonstrating a lower composite CVD outcome in adults with T2D treated with empagliflozin compared to placebo (HR 0.... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
10/07/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Hypertension, Cardiovascular Diseases
Register for Updates
Remote Patient Monitoring and Health Coaching vs. Usual Care for the Treatment of Hypertension
NCT05394766
Recruiting
High blood pressure, also known as hypertension, affects nearly half of all Americans and increases the risk for heart disease and stroke. Only about half of people with high blood pressure have it under control. New methods to control blood pressure are needed to reduce heart attack and stroke rates. The purpose of this study is to test whether a digital program that includes personalized health coaching and remote patient monitoring with a connected blood pressure cuff, all delivered on a smar... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2024
Locations: Stanford University, Redwood City, California
Conditions: Hypertension
Register for Updates
Monitoring Blood Pressure at Home
NCT06247111
Recruiting
The overall goal of this project is to determine if measuring blood pressure at home and staying in contact with a team of pharmacists and physicians to manage your blood pressure is feasible. The study will enroll 24 participants at UAB who are seen at the Emergency Department Post-Discharge Clinic. Half of the participants (12 patients) will be asked to measure their blood pressure at home, and half of the participants (12 patients) will continue to receive usual care. Participants who measure... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/18/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Hypertension
Register for Updates
Community Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study
NCT06595251
Recruiting
The Fit2Play prospective cohort study examines the effects of a park-based youth physical activity afterschool program on youth participant fitness and mental health outcomes. Duke will perform a secondary analysis of the data collected as part of the Fit2Play prospective cohort study run by Miami-Dade County Parks and Recreation.
Gender:
ALL
Ages:
Between 6 years and 14 years
Trial Updated:
09/17/2024
Locations: Miami-Dade County Parks, Recreation and Open Spaces Department, Miami, Florida
Conditions: Overweight, Obesity, Hypertension, Prehypertension, Anxiety, Well-being, Depression, Low Physical Fitness, Psychological
Register for Updates
Community Park-Based Programs for Health Promotion: the Fit2Lead Prospective Cohort Study
NCT06596265
Recruiting
The Fit2Lead prospective cohort study examines the effects of a park-based youth mental health and resilience afterschool program on youth participant mental health, resilience, physical fitness, and violence prevention outcomes. Duke will perform a secondary analysis of the data collected as part of the Fit2Lead prospective cohort study run by Miami-Dade County Parks and Recreation.
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
09/17/2024
Locations: Miami-Dade County Parks, Recreation and Open Spaces Department, Miami, Florida
Conditions: Anxiety, Wellness, Psychological, Overweight or Obesity, Hypertension, Prehypertension, Low Physical Fitness
Register for Updates
Community Park-Based Programs for Health Promotion: Active Older Adults Prospective Cohort Study
NCT06604650
Recruiting
The Active Older Adults prospective cohort study examines the effects of a park-based fitness program on cardiovascular fitness outcomes for older adults (aged 50 years and older). Duke will perform a secondary analysis of the data collected as part of the Active Older Adults prospective cohort study run by Miami-Dade County Parks and Recreation.
Gender:
ALL
Ages:
Between 50 years and 95 years
Trial Updated:
09/17/2024
Locations: Miami-Dade County Parks, Recreation and Open Spaces Department, Miami, Florida
Conditions: Hypertension, Overweight, Obesity, Cardiovascular Diseases, Sedentary Behavior, Low Physical Fitness
Register for Updates
Improving Age-Related Cognitive Decline with Exercise in Hypertensive Older Adults
NCT05043454
Recruiting
The investigator aims to assess the extent to which a brief exercise intervention improves systemic growth factor concentrations, reverses loss of systemic vascular networks and hypertension, and by extension, improves neurocognition. To test the investigator's hypothesis that increased cardiovascular fitness will correlate with improved vascular density, the investigator proposes the innovative use of retinal density scans.
Gender:
ALL
Ages:
Between 55 years and 75 years
Trial Updated:
09/05/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Hypertension
Register for Updates
Study of Disrupted Sleep in Somali Americans
NCT05411029
Recruiting
The aims of this study are to determine the types and severity of previously undiagnosed sleep deficiencies in otherwise healthy Somali Americans, apply a research framework to define psychosocial, behavioral, environmental, and biological mechanisms mediating sleep deficiencies in Somali Americans, and examine the relationship between sleep deficiencies and increased blood pressure in Somali Americans.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
09/03/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Hypertension, Sleep Disorder, Healthy
Register for Updates
Peripheral Nerve Blocks for Above-the-knee Amputations
NCT03404180
Recruiting
Surgery performed with nerve blocks and sedation may be safer and provide better pain control compared to general anesthesia and opioid therapy in high-risk patient populations such as elderly and troubled with peripheral vascular disease, diabetes, hypertension, coronary artery disease, and chronic obstructive pulmonary disease (COPD).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/22/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Peripheral Vascular Diseases, Hyperglycaemia (Diabetic), Hypertension, Coronary Artery Disease, Pulmonary Disease, Chronic Obstructive
Register for Updates
VicorderCS NIBP Validation Study to Review The Ability to Capture Blood Pressure Measurements
NCT06560034
Recruiting
80 Beats Medical introduces the VicorderCS, the next generation of our Vicorder technology designed to manage hypertension and cardiovascular risks. This advanced diagnostic equipment offers non-invasive collection and computation of a plethora of cardiovascular markers. It is faster, easier to use, and more portable than its predecessor, with enhanced connectivity options for extended marker collection and analysis. These markers enable early diagnosis of cardiovascular disease, ensuring positi... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/15/2024
Locations: Manos Health Study Site, Breckenridge, Colorado
Conditions: Cardiovascular Diseases, Blood Pressure, Hypertension
Register for Updates
Ketone Ester and Acute Salt (KEAS) in Young Adults
NCT05545501
Recruiting
Most Americans consume excess dietary salt based on the recommendations set by the American Heart Association and Dietary Guidelines for Americans. High dietary salt impairs the ability of systemic blood vessels and the kidneys to control blood pressure, which contributes to excess salt consumption being associated with increased risk for chronic kidney disease and cardiovascular disease, the leading cause of death in America. There is a critical need for strategies to counteract the effects of... Read More
Gender:
ALL
Ages:
Between 18 years and 39 years
Trial Updated:
08/12/2024
Locations: Auburn University, Auburn, Alabama
Conditions: Salt; Excess, Hypertension
Register for Updates
MR Antagonist and LSD1
NCT04840342
Recruiting
Lysine specific demethylase-1 (LSD1) is an epigenetic regulator of gene transcription involved in the pathophysiology of elevated blood pressure and likely renal damage in Blacks. This project investigates whether a genetically driven anti-hypertensive approach proves superior in controlling blood pressure and mitigating renal injury in Blacks who carry the risk allele for LSD1 (rs587168). The findings of these investigations may lead to a new approach in treating a subset (\~30%) of the essenti... Read More
Gender:
ALL
Ages:
17 years and above
Trial Updated:
08/06/2024
Locations: Brigham and Women's, Boston, Massachusetts
Conditions: Hypertension, Mineralocorticoid Excess
Register for Updates