There are currently 167 active clinical trials seeking participants for Hypertension research studies. The states with the highest number of trials for Autism participants are California, Florida, Texas and Ontario.
Stress and Blood Pressure Management for Caregivers
NCT05734638
Recruiting
Due to health and wealth disparities, no demographic group is more at risk than African American women for the double jeopardy of stress from caregiving for persons living with dementia (PLWD) and stress associated with hypertension (HTN). This double jeopardy puts those they care for in jeopardy as well: Reduced quality of life and longevity, disability, cognitive decline, and stroke associated with HTN1 impede caregiving activities and resultant health and well-being for persons living with Al... Read More
Gender:
Female
Ages:
40 years and above
Trial Updated:
09/26/2023
Locations: Ohio State University, Columbus, Ohio
Conditions: Hypertension, Stress, Psychological
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Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
NCT06055036
Recruiting
Lower attainment of cardiovascular health (CVH), indicated by the American Heart Association's Life's Simple 7 (LS7; physical activity, diet, cholesterol, blood pressure, body mass index, smoking, glycemia) and Life's Essential 8 (LE8; LS7+sleep) metrics, is a major contributor to Black men having the shortest life-expectancy of any non-indigenous race/sex group. Unfortunately, a paucity of literature exists on interventions aimed at improving CVH among Black men. The team of clinician scientist... Read More
Gender:
Male
Ages:
18 years and above
Trial Updated:
09/19/2023
Locations: The Ohio State University, Columbus, Ohio
Conditions: Cardiometabolic Syndrome, Physical Inactivity, Hypertension, Type 2 Diabetes, PreDiabetes, Obesity, Cardiovascular Diseases, Smoking, Sleep, Hyperlipidemias, Diet, Healthy, Blood Pressure
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Stress and Hypertension in Dementia Caregivers
NCT05721482
Recruiting
No demographic group is more at risk for the double jeopardy of caregiving stress and hypertension (HTN) than African American women caring for a family member with Alzheimer's disease and related dementias (ADRD). Both situations lead to reduced quality of life and cardiovascular disease-a complication of uncontrolled hypertension. Maintaining the health of these caregivers is critical to support the well-being of the care recipients. Although some multi-component interventions have addressed A... Read More
Gender:
Female
Ages:
40 years and above
Trial Updated:
05/09/2023
Locations: College of Nursing Ohio State University, Columbus, Ohio
Conditions: Hypertension, Stress, Psychological
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OPtimizing Technology to Improve Medication Adherence and BP Control (OPTIMA-BP)
NCT05293756
Recruiting
Hypertension (HTN) has a greater impact on African Americans (AA) than any other U.S. racial group. Uncontrolled blood pressure (BP) contributes to higher rates of disability, death, and health resource use among AA. HTN is the single most influential risk factor for cardiovascular disease (CVD), as well as a risk factor for the incidence of stroke, diabetes, chronic kidney disease, and dementia. Importantly, older adults account for 15% of the U.S. population, and two-thirds of older adults ove... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
04/10/2024
Locations: Case Western Reserve University, Cleveland, Ohio
Conditions: Hypertension, Self-Management, Technology, Quality of Life
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Using mHealth to Improve Adherence and Reduce Blood Pressure in Individuals With Hypertension and Bipolar Disorder
NCT04675593
Recruiting
This proposed 2-stage randomized controlled trial (RCT) will evaluate a personalized patient-centered adherence intervention iTAB-CV + Self-Monitoring (iTAB-CV + SM) vs. Self-Monitoring (SM) alone in poorly adherent hypertensive persons with BD. This practical, technology-facilitated intervention has potential to improve adherence to antihypertensive medication and reduce SBP among high-risk individuals. The intervention is suitable for primary care or mental health settings and has potential fo... Read More
Gender:
All
Ages:
Between 21 years and 80 years
Trial Updated:
02/27/2024
Locations: Case Western Reserve University, Cleveland, Ohio
Conditions: Bipolar Disorder, Non-Adherence, Medication, Hypertension
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Self-Management and Resilience Trajectories in African American Adults With Hypertension
NCT05308914
Recruiting
Hypertension (HTN) rates have increased worldwide, but the most significant increase in the incidence of morbidity and mortality has been in African Americans (AA)1,2 (43% vs 27% for other U.S. population groups). Despite evidence of positive benefits from lifestyle modification (healthy diet, reduced sodium intake, increased physical activity, smoking cessation) and prescribed antihypertensive therapy (AHT) many AA with HTN do not adhere to their treatment regimens. Consistent, effective lifelo... Read More
Gender:
All
Ages:
25 years and above
Trial Updated:
02/26/2024
Locations: University Hospitals Cleveland Medical Center, Cleveland, Ohio
Conditions: Hypertension, Self-Management, Quality of Life, Compliance, Medication, Compliance, Treatment, Compliance, Patient
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Yoga for a Healthy Heart
NCT06155240
Recruiting
The Yoga for a Healthy Heart study will address various barriers to both medication management and blood pressure regulation for African American patients with hypertension.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
11/30/2023
Locations: South Pointe Hospital, Warrensville Heights, Ohio
Conditions: Hypertension
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Open-Label Extension Study to Assess Safety, Efficacy, and Tolerability of Lorundrostat in Subjects With Uncontrolled Hypertension
NCT05968430
Recruiting
This study is to evaluate the long-term safety, efficacy and tolerability of lorundrostat (an aldosterone synthase inhibitor) in subjects with uncontrolled hypertension.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/29/2024
Locations: Del Sol Research Management, LLC, Tucson, Arizona +32 locations
Conditions: Hypertension
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Diabetes and Heart Disease Risk in Blacks
NCT00001853
Recruiting
It is unknown if obesity contributes to the development of heart disease in African American men and women. This study was created to determine whether there is a relationship between sex and body size and the incidence of heart disease in African American men and women. Researchers will attempt to associate obesity with the presence of heart disease risk factors. Risk factors that will be studied include; total body fat, body fat distribution, fat content of the blood (triglyceride concentrati... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
04/27/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Diabetes, Obesity, Hypertension, Cardiovascular Diseases
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Nicotinamide Riboside for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults
NCT03821623
Recruiting
Aging is the primary risk factor for cardiovascular diseases (CVD), the number one cause of death in developed societies. Systolic blood pressure (SBP) increase with age and is a key intermediary factor linking aging to increased CVD risk. The primary mechanisms underlying the age-associated increase in SBP is stiffening of the large elastic arteries, which is mediated by increases in oxidative stress, inflammation, and vascular smooth muscle tone. Regular caloric restriction is effective at low... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
04/26/2024
Locations: Integrative Physiology of Aging Laboratory, Boulder, Colorado
Conditions: Hypertension, Aging
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Angiotensin II in General Anesthesia
NCT03733145
Recruiting
Hypotension in adult patients undergoing general anesthesia is common. This can lead to hypoperfusion of vital organs, organ damage, and states of increased metabolic duress. This may be worse in patients with underlying essential hypertension and worse in patients taking Angiotensin Converting Enzyme Inhibitors (ACE) and Angiotensin Receptor Blockers (ARBs). Intravenous (IV) administration of Ang II may be an effective treatment of hypotension in this patient population.
Gender:
All
Ages:
40 years and above
Trial Updated:
04/26/2024
Locations: Wake Forest Baptist Medical Center, Winston-Salem, North Carolina
Conditions: Hypertension
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A Pivotal Study to Evaluate the Efficacy of Lorundrostat in Subjects With Uncontrolled Hypertension on a Standardized Antihypertensive Medication Regimen
NCT05769608
Recruiting
a Phase 2 trial to evaluate the blood pressure-lowering effect of lorundrostat (an aldosterone synthase inhibitor), administered on a background of a standardized anti-hypertensive (AHT) medication regimen, in subjects with uncontrolled and/or treatment-resistant hypertension.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/24/2024
Locations: Cardiology, P.C. - Birmingham, Birmingham, Alabama +90 locations
Conditions: Hypertension
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