There are currently 155 active clinical trials seeking participants for Hypertension research studies. The states with the highest number of trials for Hypertension participants are California, Florida, Texas and Ontario.
Stress and Blood Pressure Management for Caregivers
NCT05734638
Recruiting
Due to health and wealth disparities, no demographic group is more at risk than African American women for the double jeopardy of stress from caregiving for persons living with dementia (PLWD) and stress associated with hypertension (HTN). This double jeopardy puts those they care for in jeopardy as well: Reduced quality of life and longevity, disability, cognitive decline, and stroke associated with HTN1 impede caregiving activities and resultant health and well-being for persons living with Al... Read More
Gender:
FEMALE
Ages:
40 years and above
Trial Updated:
12/10/2024
Locations: Ohio State University, Columbus, Ohio
Conditions: Hypertension, Stress, Psychological
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Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
NCT06055036
Recruiting
Lower attainment of cardiovascular health (CVH), indicated by the American Heart Association's Life's Simple 7 (LS7; physical activity, diet, cholesterol, blood pressure, body mass index, smoking, glycemia) and Life's Essential 8 (LE8; LS7+sleep) metrics, is a major contributor to Black men having the shortest life-expectancy of any non-indigenous race/sex group. Unfortunately, a paucity of literature exists on interventions aimed at improving CVH among Black men. The team of clinician scientist... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
09/19/2023
Locations: The Ohio State University, Columbus, Ohio
Conditions: Cardiometabolic Syndrome, Physical Inactivity, Hypertension, Type 2 Diabetes, PreDiabetes, Obesity, Cardiovascular Diseases, Smoking, Sleep, Hyperlipidemias, Diet, Healthy, Blood Pressure
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OPtimizing Technology to Improve Medication Adherence and BP Control (OPTIMA-BP)
NCT05293756
Recruiting
Hypertension (HTN) has a greater impact on African Americans (AA) than any other U.S. racial group. Uncontrolled blood pressure (BP) contributes to higher rates of disability, death, and health resource use among AA. HTN is the single most influential risk factor for cardiovascular disease (CVD), as well as a risk factor for the incidence of stroke, diabetes, chronic kidney disease, and dementia. Importantly, older adults account for 15% of the U.S. population, and two-thirds of older adults ove... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
04/01/2025
Locations: Case Western Reserve University, Cleveland, Ohio
Conditions: Hypertension, Self-Management, Technology, Quality of Life
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Using MHealth to Improve Adherence and Reduce Blood Pressure in Individuals with Hypertension and Mood Disorders
NCT04675593
Recruiting
This proposed 2-stage randomized controlled trial (RCT) will evaluate a personalized patient-centered adherence intervention iTAB-CV + Self-Monitoring (iTAB-CV + SM) vs. Self-Monitoring (SM) alone in poorly adherent hypertensive persons with BD or MDD. This practical, technology-facilitated intervention has potential to improve adherence to antihypertensive medication and reduce SBP among high-risk individuals. The intervention is suitable for primary care or mental health settings and has poten... Read More
Gender:
ALL
Ages:
Between 21 years and 80 years
Trial Updated:
09/09/2024
Locations: Case Western Reserve University, Cleveland, Ohio
Conditions: Bipolar Disorder, Non-Adherence, Medication, Hypertension, Major Depressive Disorder
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Nutrition Outreach and Understanding: Research In Serving Hearts Through Healthy Eating And Tailored Support
NCT06460272
Recruiting
This study is a human-centered, three-arm, parallel-group, randomized control, implementation trial (n=75) to compare MTM (Medically Tailored Meals) only (14 meals delivered weekly for 10 weeks) vs. MTM + SMA (Shared Medical Appointments; once weekly sessions for 10 weeks) vs. a wait-list control group (MTM-Later) in patients with hypertension, type 2 diabetes, obesity, and/or metabolic syndrome. All intervention components will be culturally congruent (e.g., MTMs will include food that converge... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Hypertension, Type2diabetes, Metabolic Syndrome, Obesity
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Yoga for a Healthy Heart
NCT06155240
Recruiting
The Yoga for a Healthy Heart study will address various barriers to both medication management and blood pressure regulation for African American patients with hypertension.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
11/30/2023
Locations: South Pointe Hospital, Warrensville Heights, Ohio
Conditions: Hypertension
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Childhood-Onset Essential Hypertension Natural History Study
NCT06778239
Recruiting
Background: Childhood-onset essential hypertension (COEH) is high blood pressure that develops in children and teens. High blood pressure is a major risk factor for heart disease. COEH is more likely to be caused by changes in genes rather than by factors like stress or diet. Researchers want to learn more about how changes in genes relate to COEH. They hope to use that information to develop better treatments for children with high blood pressure. Objective: This natural history study will l... Read More
Gender:
ALL
Ages:
Between 2 years and 99 years
Trial Updated:
04/17/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Hypertension, Essential Hypertension
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SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
NCT05198674
Recruiting
The purpose of this single-arm interventional study is to evaluate the long-term safety, efficacy, and durability of the Symplicity Spyral system in subjects treated with renal denervation. Additionally, long-term follow-up data will also be collected from eligible subjects previously treated in the SPYRAL PIVOTAL-SPYRAL HTN-OFF MED and SPYRAL HTN-ON MED studies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/16/2025
Locations: University of Alabama at Birmingham (UAB) Hospital, Birmingham, Alabama +97 locations
Conditions: Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
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Global Paradise System US Post Approval Study
NCT06297291
Recruiting
The objective of the Global Paradise® System US Post Approval Study (US GPS) is to evaluate the real-world use of the Paradise Ultrasound Renal Denervation System indicated for patients who are unable to lower their blood pressure with lifestyle changes and medication. This system is comprised of a catheter, cable, balloon, and generator and has received FDA approval in the United States. Information collected in this study will be analyzed to better understand the long-term safety and effective... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/15/2025
Locations: Sutter Institute for Medical Research, Sacramento, California +23 locations
Conditions: Hypertension, Cardiovascular Diseases, Vascular Diseases
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Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks
NCT03374215
Recruiting
Background: The adrenal gland makes the hormone aldosterone. This helps regulate blood pressure. An adrenal gland tumor that makes too much aldosterone can cause high blood pressure and low potassium. The cause of these tumors is unknown, but sometimes they are inherited. Objective: To study the genes that may cause primary aldosteronism in Black individuals. Eligibility: People ages 18-70 who: Are Black, African American, or of Caribbean descent And have difficult to control blood pressu... Read More
Gender:
ALL
Ages:
Between 7 years and 70 years
Trial Updated:
04/10/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Adrenal Gland Neoplasm, Hypertension, Bone Diseases, Metabolic, Cardiovascular Disease, Hyperinsulinemia
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Effect of Electro-Acupuncture on Blood Pressure
NCT00932139
Recruiting
Based on previous published research in animals and human, the investigators hypothesize that electroacupuncture (EA) will have a positive effect on hypertension.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
04/10/2025
Locations: Susan Samueli Integrative Health Institute, Irvine, California +1 locations
Conditions: Hypertension
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Virtual Diabetes Group Visits Across Health Systems
NCT06094491
Recruiting
The purpose of this project is to evaluate the effectiveness of a virtual diabetes group visits on patients with type 2 diabetes mellitus (T2DM).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/03/2025
Locations: Access Community Health Network, Chicago, Illinois +1 locations
Conditions: T2DM (Type 2 Diabetes Mellitus), Hypertension, Heart Disease Chronic, Stroke, Hyperlipidemias, Peripheral Vascular Diseases, Obesity
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