There are currently 163 active clinical trials seeking participants for Hypertension research studies. The states with the highest number of trials for Hypertension participants are California, Florida, Texas and Ontario.
Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study)
Recruiting
The main purpose of research is to examine and understanding the development of hypertension in obese adults with insulin resistance. Findings from our studies will identify unique mechanisms that can be targeted to limit increases in vascular dysfunction and reduce the excessively high prevalence of hypertension and risk for cardiovascular disease (CVD). This study is testing the health of the blood vessels and the activity of the nerves that control the blood vessels in adults with insulin re... Read More
Gender:
ALL
Ages:
Between 35 years and 65 years
Trial Updated:
06/04/2025
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Hypertension, Cardiovascular Diseases
Treatment With Aspirin After Preeclampsia: TAP Trial
Recruiting
The objective of this research project is to conduct a single-site pilot trial to assess the feasibility and effect of low-dose aspirin to augment vascular recovery in the immediate postpartum period after preeclampsia through two specific aims: 1) to pilot test the feasibility of conducting a randomized controlled trial of postpartum low dose aspirin vs. placebo, and 2) to assess the effect of postpartum aspirin on endothelial function and blood pressure. Our central hypothesis is that postpart... Read More
Gender:
FEMALE
Ages:
Between 18 years and 55 years
Trial Updated:
06/02/2025
Locations: University of Pittsburgh Magee-Womens Hospital, Pittsburgh, Pennsylvania
Conditions: Hypertensive Disorder of Pregnancy, Pre-Eclampsia, Hypertension, Eclampsia, Gestational Hypertension, Cardiovascular Diseases, Toxemia, Pregnancy Complications, Vascular Diseases, Hypertension, Pregnancy Induced, Hypertension;Pre-Eclamptic
'Ai Pono Cooking Demonstrations
Recruiting
Native Hawaiians' traditional lifestyles and diets ensured the mutual health and well-being of the land and its inhabitants, which stand in stark contrast to the disproportionately high prevalence of diet-related, cardiometabolic diseases they experience today. In this project, the investigators will adapt and test an evidence-based multilevel intervention entitled PILI 'Āina to improve the self-management of prevalent cardiometabolic diseases and reduce risk factors for developing new diet-rela... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/28/2025
Locations: Kula no na Poe Hawaii, Honolulu, Hawaii +1 locations
Conditions: Type 2 Diabetes, Hypertension, Dyslipidemias, Overweight and Obesity
PILI 'Āina Household
Recruiting
Native Hawaiians' traditional lifestyles and diets ensured the mutual health and well-being of the land and its inhabitants, which stand in stark contrast to the disproportionately high prevalence of diet-related, cardiometabolic diseases they experience today. In this project, the investigators will adapt and test an evidence-based multilevel intervention entitled PILI 'Āina to improve the self-management of prevalent cardiometabolic diseases and reduce risk factors for developing new diet-rela... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/28/2025
Locations: Kula no nā Po'e Hawai'i, Honolulu, Hawaii +1 locations
Conditions: Type 2 Diabetes, Hypertension, Dyslipidemias, Overweight and Obesity
Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions
Recruiting
The lack of postpartum primary care coordination is a missed opportunity to increase primary care engagement and manage chronic conditions early in life, especially for the \>30% of pregnant people who have or are at risk for these conditions. This study aims to increase postpartum primary care engagement, quality, and experience by strengthening postpartum transitions to primary care using a behavioral economics-informed, multi-component intervention integrated into usual inpatient postpartum c... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/27/2025
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Hypertension, Diabetes, Postpartum, Pregnancy, Anxiety, Depression, Obesity
Groceries Plus Multi-Component Lifestyle Intervention for Adults With Hypertension and Type 2 Diabetes
Recruiting
People with high blood pressure and diabetes often have low levels of key nutrients as a result of not eating enough fresh fruits and vegetables. Research studies suggest that these nutrients can lower blood pressure and blood sugar. This study will investigate if providing encouragement to adopt this healthy and nutritious way of eating and providing guidance on weight management will lower blood pressure and blood sugar. The DASH-Life research study will recruit adults with hypertension and ty... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/27/2025
Locations: Johns Hopkins ProHealth Clinical Research Unit, Baltimore, Maryland
Conditions: Hypertension, Type 2 Diabetes Mellitus (T2DM)
Community Engagement Alliance Against Disparities
Recruiting
The Community Engagement Alliance against Disparities - Washington District of Columbia, Maryland, Virginia (CEAL DMV), is a multi-community and multi-university consortium. Through collaboration and shared leadership, the CEAL-DMV the consortium- comprising five institutions: George Washington University, Howard University, Johns Hopkins University, Morgan State University, and the University of Maryland, Baltimore-has established a regional structure for bi-directional community involvement to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/21/2025
Locations: George Washington University, Milken Institute of Public Health, Washington, District of Columbia +1 locations
Conditions: Diabetes, Pre-diabetes, Hypertension, Overweight and Obesity
Remote Fetal Monitoring in High Risk Pregnancies
Recruiting
Antenatal nonstress tests (NSTs) are performed to assess fetal health and are used as a cost-effective test that can be widely administered. However, an NST is operator-dependent due to the nature of Doppler ultrasound and is primarily performed in a clinic and hospital setting. The ability to conduct a clinically valuable test at home would address access to care issues faced by numerous women in the United States and reduce the workload on healthcare clinicians facing a shortage of human reso... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/19/2025
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: High Risk Pregnancy, Remote Patient Monitoring, Diabetes, Hypertension
Implementation Strategies for Self-Measured Blood Pressure Monitoring in Racially and Ethnically Diverse Populations
Recruiting
This clinical trial aims to assess the impact of patient-focused and clinical-focused implementation strategies on blood pressure control. The investigators will assess the costs of these strategies and how effective they were at safely and equitably increasing home blood pressure monitoring.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2025
Locations: Zuckerberg San Francisco Hospital, San Francisco, California
Conditions: Blood Pressure Monitoring, Home, Hypertension
Metabolic Effects of Angiotensin-(1-7)
Recruiting
The overall purpose of this study is to learn more about the metabolic effects of angiotensin-(1-7) in the insulin resistant state associated with obesity. Pharmacologic approaches to increase angiotensin-(1-7) levels or its actions are currently in development for treatment of metabolic-related diseases such as obesity and type II diabetes, based on findings from animal studies. It is unclear if this peptide contributes to the regulation of metabolism in humans. The investigators will test if a... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
05/10/2025
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Obesity, Insulin Resistance, Hypertension, Metabolic Cardiovascular Syndrome
Reducing Blood Pressure in Patients With High Cardiovascular Risk
Recruiting
BP-REACH is a study of a team-based (pharmacist and health coach) program for lowering blood pressure for people with a prior stroke or heart attack in the Los Angeles Department of Health Services healthcare system. The goal of this clinical trial is to test if this team based program is better at helping people reduce their blood pressure than usual care for people with prior heart attack or stroke. The main questions it aims to answer are: * Do people in the REACH BP program have lower bloo... Read More
Gender:
ALL
Ages:
35 years and above
Trial Updated:
05/09/2025
Locations: Rancho Los Amigos National Rehabilitation Center, Downey, California +3 locations
Conditions: Myocardial Infarction, Hypertension, Stroke
Arterial Stiffness and Blood Pressure
Recruiting
Hypertension is a common and treatable disorder that remains the leading preventable cause of heart disease. Blood pressure treatment relies mainly on upper arm blood pressure readings and ignores blood vessel physiology and underlying individual genetic information. Older Veterans with hypertension are less likely to be treated to goal blood pressure because there are conflicting recommendations for what constitutes "optimal" in older adults. The investigators have developed a novel way to non-... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
05/05/2025
Locations: Birmingham VA Medical Center, Birmingham, AL, Birmingham, Alabama +2 locations
Conditions: Hypertension, Vascular Stiffness, Aging